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141 Possible Causes for Focal Parakeratosis

  • Pityriasis Rubra Pilaris

    Histopathology of involved skin showed focal parakeratosis and orthokeratosis alternating in both horizontal and vertical directions with an underlying perivascular inflammatory[] PRP patient with alternating ortho and parakeratosis, focal follicular plugging Differential diagnosis Psoriasis: acanthosis is more marked, and often strikingly regular,[] […] in both vertical and horizontal directions Focal or confluent hypergranulosis, thick suprapapillary plate, broad epidermal ridges, narrow dermal papillae and perivascular[]

  • Gianotti-Crosti Syndrome

    The histopathologic findings are nonspecific and include focal parakeratosis, mild spongiosis, superficial perivascular infiltrate, papillary dermal edema, and extravasated[] parakeratosis and epidermal spongiosis.[] Histopathologic analysis showed compact orthokeratosis, focal parakeratosis, hypergranulosis, psoriasiform epidermal hyperplasia, and a dense lichenoid lymphohistiocytic infiltrate[]

  • Hyperkeratosis Lenticularis Perstans

    Histopathological examination revealed a hyperkeratosis with a focal parakeratosis overlying the thinned epidermis.[] parakeratosis (figure 1).[] […] keratinocytes Histology of hyperkeratosis lenticularis perstans (Flegel disease) In Flegel disease, sections show discrete zones of compact lamellar hyperkeratosis with focal[]

  • Pityriasis Lichenoides

    Histologic Features Focal parakeratosis A slightly thin epidermis Vacuolar alteration of the basal layer Necrotic keratinocytes in variable numbers within the epidermis A[] parakeratosis often noted.[] parakeratosis, preservation of the granular layer, and focal disappearance of the dermal-epidermal interface Management The course of pityriasis lichenoides varies with an[]

  • Generalized Follicular Keratosis

    Histopathological examination revealed a hyperkeratosis with a focal parakeratosis overlying the thinned epidermis.[] Histopathological examination of skin biopsies obtained from the trunk and extremities showed prominent hyperkeratosis and follicular plugging with focal parakeratosis.[] Sign out SKIN LESION, LEFT ARM, PUNCH BIOPSY: - SKIN WITH ACANTHOSIS, HYPERKERATOSIS, FOCAL PARAKERATOSIS, PROMINENT DILATED VESSELS IN THE SUPERFICIAL DERMIS, SUPERFICIAL[]

  • Bowenoid Papulosis

    Epidermal psoriasiform hyperplasia, hyperkeratosis, and focal parakeratosis are also common features.[] parakeratosis and focal acanthosis with almost full thickness epidermal atypia (keratinocytes shows loss of cellular polarity, dyskeratosis, multinucleated giant cells, and[] By contrast, in 22 specimens obtained from lesions of Bowen’s disease we observed a focal or diffuse parakeratosis showing flat or oblong nuclei.[]

  • Parapsoriasis

    parakeratosis.[] Histopathologic examination of the skin specimen revealed epidermal atrophy, focal parakeratosis, perivascular dermal infiltrate of mononuclear cells with exocytosis in the[] […] intensity, in the epidermis - focal parakeratosis, small acanthosis with focal extracellular edema and exocytosis.[]

  • Erythema Annulare Centrifugum

    The epidermis showed irregular atrophy with spongiosis and focal parakeratosis. There was a sharply demarcated perivascular infiltrate of lymphocytes in the dermis.[] Histopathology from the erythematous margin showed mild hyperkeratosis, focal parakeratosis, and perivascular lymphocytic infiltrate in the superficial as well as deep dermis[] An incisional biopsy was taken from the annular eruption and showed mild acanthotic epidermis with focal parakeratosis and superficial perivascular lymphocytic infiltrates[]

  • Prurigo Nodularis

    parakeratosis; hypergranulosis; fibrosis of the papillary dermis with vertically arranged collagen fibers; increased number of fibroblasts and capillaries; a superficial,[] Microscopic features: Histopathology reveals psoriasiform hyperplasia or pseudo-epitheliomatous hyperplasia ; Marked hyperkeratosis with hypergranulosis and focal parakeratosis[] Focal parakeratosis with irregular acanthosis diminished nerve fiber density and a nonspecific dermal infiltrate containing lymphocytes, macrophages, eosinophils, and neutrophils[]

  • Papillon Lefevre Disease

    Skin biopsy shows hyperkeratosis with focal parakeratosis, moderate perivascular infiltration, hypergranulosis, and acanthosis.[]

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