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141 Possible Causes for Focal Parakeratosis

  • Pityriasis Rubra Pilaris

    Histopathology of involved skin showed focal parakeratosis and orthokeratosis alternating in both horizontal and vertical directions with an underlying perivascular inflammatory[casereports.bmj.com] PRP patient with alternating ortho and parakeratosis, focal follicular plugging Differential diagnosis Psoriasis: acanthosis is more marked, and often strikingly regular,[pathologyoutlines.com] […] in both vertical and horizontal directions Focal or confluent hypergranulosis, thick suprapapillary plate, broad epidermal ridges, narrow dermal papillae and perivascular[pathologyoutlines.com]

  • Gianotti-Crosti Syndrome

    The histopathologic findings are nonspecific and include focal parakeratosis, mild spongiosis, superficial perivascular infiltrate, papillary dermal edema, and extravasated[ncbi.nlm.nih.gov] parakeratosis and epidermal spongiosis.[ncbi.nlm.nih.gov] Histopathologic analysis showed compact orthokeratosis, focal parakeratosis, hypergranulosis, psoriasiform epidermal hyperplasia, and a dense lichenoid lymphohistiocytic infiltrate[ncbi.nlm.nih.gov]

  • Hyperkeratosis Lenticularis Perstans

    Histopathological examination revealed a hyperkeratosis with a focal parakeratosis overlying the thinned epidermis.[ncbi.nlm.nih.gov] parakeratosis (figure 1).[dermnetnz.org] […] keratinocytes Histology of hyperkeratosis lenticularis perstans (Flegel disease) In Flegel disease, sections show discrete zones of compact lamellar hyperkeratosis with focal[dermnetnz.org]

  • Pityriasis Lichenoides

    Histologic Features Focal parakeratosis A slightly thin epidermis Vacuolar alteration of the basal layer Necrotic keratinocytes in variable numbers within the epidermis A[dxpath.com] parakeratosis often noted.[practicaldermatology.com] parakeratosis, preservation of the granular layer, and focal disappearance of the dermal-epidermal interface Management The course of pityriasis lichenoides varies with an[pcds.org.uk]

  • Generalized Follicular Keratosis

    Histopathological examination revealed a hyperkeratosis with a focal parakeratosis overlying the thinned epidermis.[connection.ebscohost.com] Histopathological examination of skin biopsies obtained from the trunk and extremities showed prominent hyperkeratosis and follicular plugging with focal parakeratosis.[ijdvl.com] Sign out SKIN LESION, LEFT ARM, PUNCH BIOPSY: - SKIN WITH ACANTHOSIS, HYPERKERATOSIS, FOCAL PARAKERATOSIS, PROMINENT DILATED VESSELS IN THE SUPERFICIAL DERMIS, SUPERFICIAL[librepathology.org]

  • Bowenoid Papulosis

    Epidermal psoriasiform hyperplasia, hyperkeratosis, and focal parakeratosis are also common features.[dermatologyadvisor.com] parakeratosis and focal acanthosis with almost full thickness epidermal atypia (keratinocytes shows loss of cellular polarity, dyskeratosis, multinucleated giant cells, and[cdriadvlkn.org] By contrast, in 22 specimens obtained from lesions of Bowen’s disease we observed a focal or diffuse parakeratosis showing flat or oblong nuclei.[jle.com]

  • Parapsoriasis

    parakeratosis.[jamanetwork.com] Histopathologic examination of the skin specimen revealed epidermal atrophy, focal parakeratosis, perivascular dermal infiltrate of mononuclear cells with exocytosis in the[ncbi.nlm.nih.gov] […] intensity, in the epidermis - focal parakeratosis, small acanthosis with focal extracellular edema and exocytosis.[iliveok.com]

  • Erythema Annulare Centrifugum

    The epidermis showed irregular atrophy with spongiosis and focal parakeratosis. There was a sharply demarcated perivascular infiltrate of lymphocytes in the dermis.[ijdvl.com] Histopathology from the erythematous margin showed mild hyperkeratosis, focal parakeratosis, and perivascular lymphocytic infiltrate in the superficial as well as deep dermis[indianpediatrics.net] An incisional biopsy was taken from the annular eruption and showed mild acanthotic epidermis with focal parakeratosis and superficial perivascular lymphocytic infiltrates[medicaljournals.se]

  • Prurigo Nodularis

    parakeratosis; hypergranulosis; fibrosis of the papillary dermis with vertically arranged collagen fibers; increased number of fibroblasts and capillaries; a superficial,[ncbi.nlm.nih.gov] Microscopic features: Histopathology reveals psoriasiform hyperplasia or pseudo-epitheliomatous hyperplasia ; Marked hyperkeratosis with hypergranulosis and focal parakeratosis[histopathology-india.net] Focal parakeratosis with irregular acanthosis diminished nerve fiber density and a nonspecific dermal infiltrate containing lymphocytes, macrophages, eosinophils, and neutrophils[knowledge.statpearls.com]

  • Papillon Lefevre Disease

    Skin biopsy shows hyperkeratosis with focal parakeratosis, moderate perivascular infiltration, hypergranulosis, and acanthosis.[rarediseases.info.nih.gov]

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