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10 Possible Causes for Focal Sharp-Waves, Paroxysmal Activity - Sharp-Waves, Paroxysmal Activity - Sharp-Waves Bilaterally

  • Epilepsy

    (EEG) hallmark of focal-onset seizures is the focal interictal epileptiform spike or sharp wave.[emedicine.medscape.com] […] background, diffusemultifocal sharp waves and sharp waves-slow waves; paroxysmal fast activity Neurological examination mild diffuse hypotonia, mild ataxia with wide based[ncbi.nlm.nih.gov] The cellular neurophysiologic correlate of an interictal focal epileptiform discharge in single cortical neurons is the paroxysmal depolarization shift (PDS).[emedicine.medscape.com]

  • Rolandic Epilepsy

    sharp waves and RD in siblings.[ncbi.nlm.nih.gov] Focal sharp waves in the centrotemporal area define the electroencephalographic (EEG) trait for the syndrome, are a feature of several related childhood epilepsies and are[ncbi.nlm.nih.gov] We acknowledge Professor Hermann Doose's intellectual contribution to the nosology of focal sharp wave-associated phenotypes in children.[doi.org]

  • Vascular Dementia

    Many of the previous studies of vascular dementia using proton magnetic resonance (MR) spectroscopy had been carried out on white matter. However, no proton spectroscopic data of the subcortical gray matter are available in such disease. We report two cases suffering from vascular dementia, with an unilateral[…][ncbi.nlm.nih.gov]

  • Encephalitis

    Rev Neurol (Paris). 2018 Apr;174(4):228-236. doi: 10.1016/j.neurol.2017.11.004. Epub 2018 Mar 31. Author information 1 Centre de référence maladies rares 'Syndromes neurologiques paranéoplasiques', hospices civils de Lyon, hôpital neurologique, neurologie B, 69677 Bron, France; INMG (NeuroMyoGene Institut), Inserm U1217/CNRS[…][ncbi.nlm.nih.gov]

  • Creutzfeldt Jakob Disease

    Sporadic Creutzfeldt-Jakob disease (sCJD) mainly occurs in the elderly, with the peak age of onset ranging from 55 to 75 years. The symptoms of sCJD are not unique, and laboratory tests such as magnetic resonance imaging (MRI), electroencephalogram (EEG) and cerebrospinal fluid (CSF)14-3-3 protein have low[…][ncbi.nlm.nih.gov]

  • Periventricular Leukomalacia

    Abstract To describe the impact of periventricular leukomalacia (PVL) on gross motor function, data on 59 children (37 males, 22 females) with a gestational age (GA) of 34 weeks or less with cerebral palsy (CP) due to PVL grade I ( n 20), II ( n 13), III ( n 25), and IV ( n 1) were studied; (mean GA 29wk 4d [SD[…][doi.org]

  • Fragile X Syndrome

    Fragile-X syndrome (FXS) is a frequent genetic form of intellectual disability (ID). The main recurrent mutagenic mechanism causing FXS is the expansion of a CGG repeat sequence in the 5'-UTR of the FMR1 gene, therefore, routinely tested in ID patients. We report here three FMR1 intragenic pathogenic variants not[…][ncbi.nlm.nih.gov]

  • Pyridoxine Dependency Syndrome

    The other pre-pyridoxine paroxysmal EEG abnormalities include focal spikes or sharp waves, multi-focal spikes and single sharp waves recorded over a whole quadrant or over[indianpediatrics.net] Focal, arising from multiple regions Pyridoxine-dependent epilepsy Continuous spike-wave Burst suppression Infantile spasms Multifocal myoclonic Focal Tonic Early Myoclonic[demosmedical.com] The most noteworthy interictal pattern consists of bursts or runs of high voltage relatively bilaterally synchronous 1-4 Hz activity with intermixed spikes and or sharp waves[indianpediatrics.net]

  • Benign Familial Infantile Epilepsy Type 4

    […] spikes and sharp waves.[karger.com] The EEG examination showed diffuse abnormal background activity, with sporadic isolated bilateral sharp waves over the occipital regions (a).[onlinelibrary.wiley.com] The following variable patterns are reported in interictal encephalography: (1) normal, (2) discontinuous, (3) focal or multifocal sharp waves or epileptiform patterns, and[emedicine.medscape.com]

  • Encephalopathy

    *Repetitive and fairly stereotyped waveforms appearing at regular intervals, sharps/spike waves or complex discharges.[slideshare.net] . • Effect depend on dose, and duration of exposure * Narcoleptics—slowing of alpha, increase in theta and delta activity and paroxysmal bursts of sharp and slow waves, these[slideshare.net] […] and paroxysmal bursts of sharp and slow waves, these drugs increase epileptiform activity in known epileptic patients, clozapine increase bilateral spike waves discharges[slideshare.net]

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