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373 Possible Causes for Focal Spikes

  • Hashimoto Thyroiditis

    Solid papillary thyroid carcinoma (SV-PTC) is a rare variant which is mainly observed in young patients with a history of exposure to ionising radiations. Neoplasms belonging to such category generally carry RET-PTC (REarranged during Transfection- Papillary Thyroid Carcinoma) fusions and seem to have a slightly[…][]

  • Epilepsy

    Focal seizures began at 5 years and were refractory to medical treatment.[] (EEG) hallmark of focal-onset seizures is the focal interictal epileptiform spike or sharp wave.[] At 9 years, video EEG monitoring showed a striking pattern of interictal slow spike-wave and paroxysmal fast activity, maximal over the right, initially unaffected, hemisphere[]

  • Juvenile Myoclonic Epilepsy

    Abstract This chapter covers the syndromes of benign epilepsy with centrotemporal spikes (BECTS), nonlesional focal epilepsy in otherwise normal children (NLFN), and the genetic[] We compared the occurrence and involvement of posterior electrodes for focal abnormalities and generalised spike-wave activity in the EEG outside photic stimulation between[] […] discharges on electroencephalography, and a lack of focal abnormality on magnetic resonance imaging (MRI).[]

  • Generalized Clonic or Tonic-Clonic Seizures

    - A current diagnosis of febrile seizures, or seizures related to an ongoing acute medical illness - Focal seizures (simple partial, complex partial, or partial becoming secondarily[] See epilepsy . atonic seizure an absence seizure characterized by sudden loss of muscle tone. focal motor seizure a simple partial seizure consisting of clonus or spasm of[] […] generalized) - Status Epilepticus within 1 year prior to screening - Lennox-Gastaut syndrome, infantile spasms, Benign Epilepsy with Centrotemporal Spikes (BECTS) and Dravet[]

  • Benign Adult Familial Myoclonic Epilepsy

    EEG shows generalized spike waves and polyspike waves, early photosensitivity, and focal abnormalities.[] Benign Rolandic epilepsy benign childhood epilepsy with centrotemporal spikes benign focal epilepsy of childhood: Epilepsy characterized by partial (focal) seizures, often[] Benign epilepsy with centrotemporal discharges: Is one of the most common focal epilepsies of childhood.[]

  • West Syndrome

    Brain MRI revealed no abnormal findings although interictal EEG demonstrated left centro-parieto-temporal localized spike foci.[] A “leading” spike had a focal origin in all 42 type I spasms and involved the pre‐ or postcentral gyrus within 0.1 s in 37 of these spasms.[] The spikes usually alternate randomly between focal, multifocal, and generalized discharges at different moments within a brief record.[]

  • Idiopathic Generalized Epilepsy

    Fragmented generalized spike-and-wave can appear focal or multi-focal but usually is not consistently seen in 1 area.[] The EEG signature of IGE is bisynchronous, symmetric, and generalized spike-wave complex; although focal, irregular, and so called "fragments" of discharges are not uncommon[] The morphology of the focal spike-and-wave typically appears similar to the generalized spike-and-wave. Ictal.[]

  • Juvenile Absence Epilepsy

    Although focal spikes can occur, if they consistently arise in 1 area, consider structural brain abnormality. Caution . If slow spike-and-wave ( Imaging.[] Previous clinical and EEG studies show a relationship between generalized and focal spike–wave discharges in some situations.[] Interictal and ictal EEG is characterized by focal generalized spike-wave discharge occasionally prominent in the frontal region.[]

  • Uremic Encephalopathy

    […] paroxysms of sharp waves and spike-waves during hyperventilation (HV). [38] In patients with cirrhosis, in addition to diffuse slow activity (theta and delta), triphasic[] […] of periodic lateralized epileptiform discharges (PLEDS). [37] In hypokalemia, diffuse slow activity can be seen together with paroxysmal delta/theta activity, as well as focal[]

  • Organic Brain Syndrome

    An organic brain syndrome ( OBS ), also known as an organic brain disease/disorder ( OBD ), an organic mental syndrome ( OMS ), or an organic mental disorder ( OMD ), is a syndrome or disorder of mental function whose cause is alleged to be known as organic ( physiologic ) rather than purely of the mind. These[…][]

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