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79 Possible Causes for Folic Acid Decreased, Hypercellular Bone Marrow

  • Hereditary Spherocytosis

    […] bone marrow compensation Need for continuous tranfusions decreases to 30% after first year of life Splenectomy Decision to proceed with splenectomy must take into account[pedclerk.bsd.uchicago.edu] acid and splenectomy, the surgical removal of the spleen.[en.wikipedia.org] acid and splenectomy, [6] the surgical removal of the spleen.[en.wikipedia.org]

  • Autoimmune Hemolytic Anemia

    Subsequently, the patient underwent a bone marrow biopsy that showed a hypercellular marrow with erythroid hyperplasia, but no evidence of dysplasia or lymphoma.[jmedicalcasereports.com] Some of these include: Vitamin B12 level —blood level may be low when deficient in B12 Folic acid level —blood level may be low if deficient in this B vitamin Methylmalonic[labtestsonline.org] The numbers of neutrophils (a type of white blood cell) and platelets may also be decreased. Additional tests are usually done to make the diagnosis.[labtestsonline.org]

  • Myeloproliferative Disease

    The chronic myeloproliferative diseases are characterized by relatively effective hematopoiesis, which results in a hypercellular bone marrow and elevation of one or more[clinlabnavigator.com] Bone marrow histology shows hypercellularity in most of these disorders. In the case of myelofibrosis, bone marrow fibrosis is demonstrated on the reticulin stain.[emedicine.com] This is in contrast to the myelodysplastic syndromes, in which the bone marrow is hypercellular, but the production is ineffective in one or more cell lines, resulting in[clinlabnavigator.com]

  • Polycythemia Vera

    bone marrow 5.[slideshare.net] ; decreased erythropoietin , bone marrow erythroid hyperplasia , increased leukocyte alkaline phosphatase , increased vit.B12 level, decreased folic acid level, elevated alk.phosphatase[enotes.tripod.com] Based on the presence of severe hypercellularity of the bone marrow and positivity for the JAK2V617F mutation, we finally diagnosed the patient with PV.[ncbi.nlm.nih.gov]

  • Chronic Myeloid Leukemia

    marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] Because of such abnormal shapes, these cells are destroyed before releasing into the peripheral blood circulation, leading to cytopenias and hypercellular bone marrow.[lecturio.com] marrow hypercellularity, granulocyte proliferation, and decrease in erythroid precursors.[doi.org]

  • Chronic Phase of Chronic Myeloid Leukemia

    marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] A bone marrow biopsy and aspiration demonstrated a hypercellular marrow with no other significant morphologic abnormalities.[hematologyandoncology.net] marrow Early myeloid cells (eg, myeloblasts, myelocytes, metamyelocytes, nucleated red blood cells) Bone marrow findings Ph chromosome (a reciprocal translocation of chromosomal[emedicine.medscape.com]

  • Congenital Hemolytic Anemia

    Abstract The erythrocyte membrane contains a neutral phosphatase, which was studied with p-nitrophenyl-phosphate as the substrate. The enzyme was investigated in four members of the same family, suffering from a congenital spherocytic hemolytic anemia. Although the condition was transmitted as a dominant trait,[…][ncbi.nlm.nih.gov]

  • Macrocytic Anemia

    The most common cause of this is folic acid or B12 deficiency Folic Acid Deficiency Causes Decreased intake likely secondary to alcohol abuse Decreased absorption – intake[physicianassistantexamreview.com] The bone marrow biopsy showed a slightly hypercellular bone marrow with normal granulopoiesis, normal megakaryopoiesis and a mild dyserythropoiesis without any ring-sideroblasts[ncbi.nlm.nih.gov] Bone Marrow Hypercellular bone marrow with megaloblastic anemia. Reduced trilineage hematopoiesis with marked erythroid predominance. Stainable iron is present.[path.upmc.edu]

  • Alcohol Abuse

    Bone marrow: intracytoplasmic vacuoless Multiple coarses granules Plasma cell: iron granules forming plaque Hemosiderin granules in normoblast Peripheral smear description[pathologyoutlines.com] […] precursors Also ringed sideroblasts and iron granules in plasma cells Microscopic (histologic) images Images hosted on other servers : Marked megaloblastic features Markedly hypercellular[pathologyoutlines.com]

  • Folate-Deficiency Anemia

    marrow biopsy and aspirate may show a hypercellular bone marrow with a megaloblastic maturation of cells, which morphologically resembles changes of vitamin B12 deficiency[pathologyoutlines.com] Folic acid might decrease the effectiveness of pyrimethamine (Daraprim) for treating parasite infections. Dosing considerations for Folic Acid.[emedicinehealth.com] Bone marrow aspirate and biopsy: Marrow is hypercellular with characteristic features of megaloblastic erythropoiesis and presence of large metamyelocytes.[clinicaladvisor.com]

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