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12 Possible Causes for Follicle-stimulating Hormone Decreased, Kallmann Syndrome, Mutation in the KISS1 Receptor Gene

  • Kallmann Syndrome

    Some key molecules have been discovered through the study of the genetics of CHH. 1 Inactivating mutations in genes encoding kisspeptin-1 ( KISS1 ) 40 and its receptor ( KISS1R[doi.org] Kallmann syndrome is the result of a genetic defect.[symptoma.com] Mutations in some genes seem to cause just KS ( KAL1 ) or just nHH (such as ligand/receptor pairs GNRH1/GNRHR, LEP/LEPR, KISS1/KISS1R, and TACR3/ TAC3 ; and rarely NR0B1 or[doi.org]

  • Hypogonadotropic Hypogonadism

    […] in the genes encoding GNRH1 or its receptor will result in the failure of the HPG axis and give rise to normosmic CHH. [2] Inactivating mutations of KISS1 or KISS1R causes[en.wikipedia.org] Patients with Kallmann's syndrome or idiopathic hypogonadotropic hypogonadism usually have absent puberty.[endobible.com] However, their decrease can be reversed by follicle-stimulating hormone. Serum AMH and AFC should not serve as prognostic markers of fertility in this population.[ncbi.nlm.nih.gov]

  • Hypogonadism

    […] in the genes encoding GNRH1 or its receptor will result in the failure of the HPG axis and give rise to normosmic CHH. [2] Inactivating mutations of KISS1 or KISS1R causes[en.wikipedia.org] BACKGROUND: Congenital hypogonadotrophic hypogonadism (CHH) and Kallmann syndrome (KS) are caused by disruption to the hypothalamic-pituitary-gonadal (H-P-G) axis.[ncbi.nlm.nih.gov] Fe iron; FSH follicle-stimulating hormone; GnRH gonadotropin-releasing hormone; LH luteinizing hormone.[msdmanuals.com]

  • Hypogonadotropic Hypogonadism Type 8

    Mutations involving the genes GnRH1 and KISS1, are a very rare cause of HH [41], [42].[journals.plos.org] Kallmann syndrome - absent puberty with no sense of smell. Me at 18 years old in my final year at school. I had not started puberty yet.[imgur.com] hormone (FSH) and luteinizing hormone (LH), by the pituitary gland in the brain, and in turn decreased gonadotropin levels and a resultant lack of sex steroid production.[naturalheightgrowth.com]

  • Kallmann Syndrome Type 4

    […] in the genes encoding GNRH1 or its receptor will result in the failure of the HPG axis and give rise to normosmic CHH. [2] Inactivating mutations of KISS1 or KISS1R causes[en.wikipedia.org] Kallmann syndrome can have a wide variety of additional signs and symptoms.[ghr.nlm.nih.gov] HH is caused by decreased release or function of gonadotropin-releasing hormone (GnRH), which results in decreased gonadotropin production in the pituitary, including follicle[clinicaladvisor.com]

  • Kallmann Syndrome Type 3

    gene (KISS1 receptor product)?[quizlet.com] […] a b c d e f g h i "Kallmann syndrome".[en.wikipedia.org] Diagnosis is by measurement of serum testosterone, luteinizing hormone, and follicle-stimulating hormone and by stimulation tests with human chorionic gonadotropin or gonadotropin-releasing[msdmanuals.com]

  • Hypogonadotropic Hypogonadism Type 18

    […] two novel missense mutations in the gene encoding the GNRH receptor ( GNRHR1 : NM_000406.2; HGNC: 4421), see Figure 2.[journals.plos.org] syndrome", abstract "The genetic basis is unknown for 60{\%} of normosmic hypogonadotropic hypogonadism (nHH)/Kallmann syndrome (KS).[augusta.pure.elsevier.com] Diagnosis is by measurement of serum testosterone, luteinizing hormone, and follicle-stimulating hormone and by stimulation tests with human chorionic gonadotropin or gonadotropin-releasing[merckmanuals.com]

  • Primary Male Hypogonadism

    gene (KISS1 receptor product)?[quizlet.com] Secondary hypogonadism can be caused by Kallmann syndrome, pituitary or hypothalamic tumors or disorders, obesity, diabetes and Prader-Willi syndrome.[froedtert.com] Fe iron; FSH follicle-stimulating hormone; GnRH gonadotropin-releasing hormone; LH luteinizing hormone.[merckmanuals.com]

  • Male Hypogonadism

    gene (KISS1 receptor product)?[quizlet.com] Disorders Causing Pituitary Hypogonadism Brain and pituitary tumors Hemochromatosis Kallmann syndrome Weight loss Obesity Diabetes Testicular Disorders Causing Hypogonadism[louisville.edu] Abstract During childhood, the pituitary-testicular axis is partially dormant: testosterone secretion decreases following a drop in luteinising hormone levels; follicle-stimulating[ncbi.nlm.nih.gov]

  • Congenital Absence of the Penis

    Mutations involving the genes GnRH1 and KISS1, are a very rare cause of HH [41], [42].[journals.plos.org] As with a lot (but not all) men with Kallmann syndrome I have underdeveloped genitals.[kallmannsyndrome.wordpress.com] , which leads to decreased pituitary secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), depriving the testis of its stimulus to secrete testosterone[emedicine.medscape.com]