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154 Possible Causes for Follicular Hyperkeratosis, Follicular Plugging

  • Vitamin A Deficiency

    Phrynoderma is a rare form of follicular hyperkeratosis associated with deficiencies in vitamins A or C or essential fatty acids.[] Phrynoderma is a distinctive form of follicular hyperkeratosis associated with nutritional deficiency.[] Malnutrition leads to follicular hyperkeratosis or phrynoderma, manifested by the presence of skin lesions and hyperkeratotic papules.[]

  • Pityriasis Rubra Pilaris

    Microscopically follicular plugging, in addition to checkerboard alternating orthokeratosis/parakeratosis, may serve as clues to PRP diagnosis.[] Pityriasis rubra pilaris (PRP) is a chronic papulosquamous eruption of the skin characterized by follicular hyperkeratosis, salmon pink scaly plaques with islands of unaffected[] All patients promptly showed a decrease in erythema, follicular hyperkeratosis and scaling.[]

  • X-Linked Keratosis Follicularis Spinulosa Decalvans

    A punch biopsy specimen from the scalp showed follicular plugging in the epidermis with mild acanthosis, early perifollicular fibrosis with mild lymphocytic infiltrate.[] Follicular hyperkeratosis begins during infancy or early childhood, first on the face, affected the eyebrows, cheeks, forehead, and nose.[] It clinically presents with diffuse follicular hyperkeratosis of scalp which progress to atrophy, cicatricial alopecia, and photophobia.[]

  • Azelaic Acid

    It also works on the cells that line hair follicles by changing the way they mature and proliferate, which decreases follicularplugging’ and helps prevent blackheads, whiteheads[] It has several key pathophysiological features such as follicular hyperkeratosis, elevated Propionibacterium acnes proliferation, and reactive inflammation, all of which should[]

  • Cutaneous Lupus Erythematosus

    The term lupus erythematosus was introduced by Cazenave 2 in 1851 to describe the skin lesions of fixed erythema, follicular plugging, adherent scaling, atrophy and telangiectasia[] hyperkeratosis, deposit of positive PAS material at the dermo-epidermal junction leading to atrophic-cicatricial evolution.[] .  Prominent involvement of the adnexa o Follicular plugging o Scarring alopecia (Irreversible) 57.[]

  • Frontal Fibrosing Alopecia

    The most common trichoscopic features of FFA include absence of follicular openings, followed by follicular hyperkeratosis, perifollicular erythema, and follicular plugs.[] Follicular hyperkeratosis and erythema were present in 66%, and only 25% of the men reported pruritus.[] On trichoscopy: (1) absence of follicular openings; (2) reduced hair density, absence of vellus hair at hairline margins; (3) follicular plugging, perifollicular scale, and[]

  • Pseudopelade of Brocq

    The histopathology is characteristic, and shows the following features: little or only moderate lymphocytic infiltrate, absence of significant follicular plugging, and absence[] hyperkeratosis or perifollicular inflammation.[] Patients present with red plaques of hair loss, atrophy, telangiectasias, and follicular hyperkeratosis.[]

  • Follicular Mucinosis

    A 48-year-old man presented with multiple asymptomatic patches of hair loss over his trunk and limbs associated with focal keratotic follicular plugs.[] Adult onset atopic dermatitis with secondary follicular mucinosis with cyclosporine induced spiny follicular hyperkeratosis and hair casts.[] A, Large patch of alopecia with follicular plugging. B, Loss of the left eyebrow and eyelashes. C, Widespread psoriasiform plaques.[]

  • Demodicosis

    Demodectic mites produce histologically observable tissue and inflammatory changes, epithelial hyperplasia, and follicular plugging.[] , and mild to moderate follicular hyperkeratosis ." ( J1 .29.w13) Hairs mainly in telogen and catagen. ( J1 .29.w13) Mild acanthosis on the forearms. ( J1 .29.w13) Rarely,[] Demodex folliculorum is characterised histologically by: Numerous demodex mites in the infundibula of the follicles Follicular hyperkeratosis Focal follicular lichenoid lymphocytic[]

  • Erythema Toxicum Neonatorum

    Other features may be neutrophils in the follicular epithelium, hyperkeratosis and follicular plugging.[] Other features may be neutrophils in the follicular epithelium, hyperkeratosis and follicular plugging.[]

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