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135 Possible Causes for Follicular Hyperkeratosis, Follicular Plugging

  • Vitamin A Deficiency

    ) secondary to blockage of hair follicles with plugs of keratin.[] Phrynoderma is a rare form of follicular hyperkeratosis associated with deficiencies in vitamins A or C or essential fatty acids.[] Phrynoderma is a distinctive form of follicular hyperkeratosis associated with nutritional deficiency.[]

  • Pityriasis Rubra Pilaris

    Microscopically follicular plugging, in addition to checkerboard alternating orthokeratosis/parakeratosis, may serve as clues to PRP diagnosis.[] Pityriasis rubra pilaris (PRP) is a chronic papulosquamous eruption of the skin characterized by follicular hyperkeratosis, salmon pink scaly plaques with islands of unaffected[] All patients promptly showed a decrease in erythema, follicular hyperkeratosis and scaling.[]

  • Keratosis Pilaris

    Histologic examination showed follicular and interfollicular hyperkeratosis, follicular plugging, mild inflammation, and focal scarring.[] Keratosis pilaris (KP) is a common inherited disorder of follicular hyperkeratosis It is characterized by small, folliculocentric keratotic papules that may have surrounding[] Histological examination revealed abundant mucin, keratotic follicular plugging, and periadnexal lymphocytosis.[]

  • Discoid Lupus Erythematosus

    Lupus erythematodes tumidus is characterized by smooth, erythematous plaques on sun-exposed areas without surface changes, such as follicular plugs, atrophy, or scale.[] Histopathology showed epidermal atrophy, hyperkeratosis, follicular plugging, thickening of the basement membrane zone, and superficial and deep chronic perivascular and periadnexal[] Figure (3) follicular hyperkeratosis before laser Figure (4) after laser Atrophy: Atrophy was presented in 26 patients, while 24 patients had no atrophy before treatment Table[]

  • Jadassohn-Lewandowsky Syndrome

    Histopathology examination of Follicular keratotic papule showed follicular plugging, hyperkeratosis and acanthosis.[] It is not often associated with the additional features of oral leukokeratosis, cysts, follicular hyperkeratosis, and natal teeth.[] , leukokeratosis of the tongue and mucous membranes and follicular hyperkeratosis.[]

  • X-Linked Keratosis Follicularis Spinulosa Decalvans

    A punch biopsy specimen from the scalp showed follicular plugging in the epidermis with mild acanthosis, early perifollicular fibrosis with mild lymphocytic infiltrate.[] hyperkeratosis, progressive scarring alopecia of scalp, eyebrows, and eyelashes and may be accompanied by photophobia, corneal and conjunctival inflammation and dystrophy[] hyperkeratosis associated with progressive cicatricial alopecia of the scalp, eyebrows and eyelashes.[]

  • Pseudopelade of Brocq

    The histopathology is characteristic, and shows the following features: little or only moderate lymphocytic infiltrate, absence of significant follicular plugging, and absence[] hyperkeratosis or perifollicular inflammation.[] Patients present with red plaques of hair loss, atrophy, telangiectasias, and follicular hyperkeratosis.[]

  • Atrophodermia Vermiculata

    The primary pathologic event seems to be the formation of follicular plugs.[] Histopathologic examination of the scalp: lamellar hyperkeratosis in the follicular ostium, discreet superficial perivascular mononuclear infiltration and linear scar, vertical[] Patogistologiya : atrophy of epidermis, follicular hyperkeratosis, hypoplasia of sebaceous glands. Forecast in the cosmetic relation for most of patients favorable.[]

  • Monilethrix

    Horny follicular papules appear as big yellow dots with immersion fluid.[] Alopecia, associated with follicular hyperkeratosis and perifollicular erythema, can involve only the occiput and the nape of the neck or, in severe forms, the entire scalp[] Rolled hairs appear as irregular coils of hair along with keratin plugs and inflammation. Genetic factor is suspected but not proven.[]

  • Frontal Fibrosing Alopecia

    The most common trichoscopic features of FFA include absence of follicular openings, followed by follicular hyperkeratosis, perifollicular erythema, and follicular plugs.[] Histopathologically, perifollicular lymphocytic infiltrate and follicular hyperkeratosis are observed at the edge of the affected area, while the rest of the lesion appears[] Follicular hyperkeratosis and erythema were present in 66%, and only 25% of the men reported pruritus.[]

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