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154 Possible Causes for Follicular Hyperkeratosis, Follicular Plugging

  • Vitamin A Deficiency

    Phrynoderma is a rare form of follicular hyperkeratosis associated with deficiencies in vitamins A or C or essential fatty acids.[ncbi.nlm.nih.gov] Phrynoderma is a distinctive form of follicular hyperkeratosis associated with nutritional deficiency.[ncbi.nlm.nih.gov] Malnutrition leads to follicular hyperkeratosis or phrynoderma, manifested by the presence of skin lesions and hyperkeratotic papules.[symptoma.com]

  • Pityriasis Rubra Pilaris

    Microscopically follicular plugging, in addition to checkerboard alternating orthokeratosis/parakeratosis, may serve as clues to PRP diagnosis.[ncbi.nlm.nih.gov] Pityriasis rubra pilaris (PRP) is a chronic papulosquamous eruption of the skin characterized by follicular hyperkeratosis, salmon pink scaly plaques with islands of unaffected[ncbi.nlm.nih.gov] All patients promptly showed a decrease in erythema, follicular hyperkeratosis and scaling.[ncbi.nlm.nih.gov]

  • X-Linked Keratosis Follicularis Spinulosa Decalvans

    A punch biopsy specimen from the scalp showed follicular plugging in the epidermis with mild acanthosis, early perifollicular fibrosis with mild lymphocytic infiltrate.[ijdvl.com] Follicular hyperkeratosis begins during infancy or early childhood, first on the face, affected the eyebrows, cheeks, forehead, and nose.[ijtrichology.com] It clinically presents with diffuse follicular hyperkeratosis of scalp which progress to atrophy, cicatricial alopecia, and photophobia.[ijpd.in]

  • Azelaic Acid

    It also works on the cells that line hair follicles by changing the way they mature and proliferate, which decreases follicularplugging’ and helps prevent blackheads, whiteheads[xojane.com] It has several key pathophysiological features such as follicular hyperkeratosis, elevated Propionibacterium acnes proliferation, and reactive inflammation, all of which should[ncbi.nlm.nih.gov]

  • Cutaneous Lupus Erythematosus

    The term lupus erythematosus was introduced by Cazenave 2 in 1851 to describe the skin lesions of fixed erythema, follicular plugging, adherent scaling, atrophy and telangiectasia[annals.org] hyperkeratosis, deposit of positive PAS material at the dermo-epidermal junction leading to atrophic-cicatricial evolution.[ncbi.nlm.nih.gov] .  Prominent involvement of the adnexa o Follicular plugging o Scarring alopecia (Irreversible) 57.[slideshare.net]

  • Frontal Fibrosing Alopecia

    The most common trichoscopic features of FFA include absence of follicular openings, followed by follicular hyperkeratosis, perifollicular erythema, and follicular plugs.[idoj.in] Follicular hyperkeratosis and erythema were present in 66%, and only 25% of the men reported pruritus.[ncbi.nlm.nih.gov] On trichoscopy: (1) absence of follicular openings; (2) reduced hair density, absence of vellus hair at hairline margins; (3) follicular plugging, perifollicular scale, and[wjgnet.com]

  • Pseudopelade of Brocq

    The histopathology is characteristic, and shows the following features: little or only moderate lymphocytic infiltrate, absence of significant follicular plugging, and absence[ncbi.nlm.nih.gov] hyperkeratosis or perifollicular inflammation.[orpha.net] Patients present with red plaques of hair loss, atrophy, telangiectasias, and follicular hyperkeratosis.[hairtx.com]

  • Follicular Mucinosis

    A 48-year-old man presented with multiple asymptomatic patches of hair loss over his trunk and limbs associated with focal keratotic follicular plugs.[ncbi.nlm.nih.gov] Adult onset atopic dermatitis with secondary follicular mucinosis with cyclosporine induced spiny follicular hyperkeratosis and hair casts.[e-ijd.org] A, Large patch of alopecia with follicular plugging. B, Loss of the left eyebrow and eyelashes. C, Widespread psoriasiform plaques.[pediatrics.aappublications.org]

  • Demodicosis

    Demodectic mites produce histologically observable tissue and inflammatory changes, epithelial hyperplasia, and follicular plugging.[emedicine.medscape.com] , and mild to moderate follicular hyperkeratosis ." ( J1 .29.w13) Hairs mainly in telogen and catagen. ( J1 .29.w13) Mild acanthosis on the forearms. ( J1 .29.w13) Rarely,[wildpro.twycrosszoo.org] Demodex folliculorum is characterised histologically by: Numerous demodex mites in the infundibula of the follicles Follicular hyperkeratosis Focal follicular lichenoid lymphocytic[dermnetnz.org]

  • Erythema Toxicum Neonatorum

    Other features may be neutrophils in the follicular epithelium, hyperkeratosis and follicular plugging.[patient.info] Other features may be neutrophils in the follicular epithelium, hyperkeratosis and follicular plugging.[patient.info]

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