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435 Possible Causes for Foot Drop, Myopathy

  • Charcot Marie Tooth Disease

    Abstract Gait abnormalities reported in childhood Charcot-Marie-Tooth disease (CMT) include foot-drop, reduced ankle power at push-off and increased knee and hip flexion for[ncbi.nlm.nih.gov] It is described as a neuropathy since the problem originates in the nerves and not in the muscle tissue itself, which would be a myopathy.[uihc.org] The lower motor neuron-type weakness may mimic a distal myopathy; however, electrophysiology is useful in differentiating between the two.[doi.org]

  • Anterior Compartment Syndrome

    One month later, the foot drop, repeat NCS, and CT demonstrated a significant improvement with conservative management.[ncbi.nlm.nih.gov] […] that the condition is properly diagnosed, to rule out other conditions such as shin splints , deep vein thrombosis, nerve and vascular entrapment syndromes, infections, myopathies[rehab4runners.co.uk] Delayed diagnosis and treatment led to extensive myonecrosis and permanent bilateral foot drop.[ncbi.nlm.nih.gov]

  • Connective Tissue Disease

    Signs and symptoms Frequent falls Difficulty walking Trouble climbing stairs or standing from a seated position A foot that seems to drop when walking, causing tripping Weakened[myositis.org] Glutamylcysteine synthetase GGLC (6p12)* Biochemical profile: Aminoaciduria, glutathione deficiency Clinical features: Hemolysis, spinocerebellar degeneration, peripheral neuropathy, myopathy[merck.com] Sporadic inclusion body myositis ( sIBM ) is the most common acquired myopathy in patients over the age of 50.[myositis.org]

  • Distal Myopathy

    Her daughter developed foot drop at age 4. Progressive weakness of distal limb extensor muscles and mild weakness of the neck flexor and proximal muscles were noted.[ncbi.nlm.nih.gov] myopathy locus.[ncbi.nlm.nih.gov] Patients had onset of distal leg muscle weakness and atrophy in the anterior compartment muscles after age 35, which caused a foot drop at age 50.[ncbi.nlm.nih.gov]

  • Tibial Muscular Dystrophy

    The proband, a 60 year-old female, had the first muscular signs at the age of 59 years, with difficulty in walking and right foot drop.[ncbi.nlm.nih.gov] CONCLUSIONS: Tibial muscular dystrophy might represent a new form of distal myopathy and it is rather common, at least in Finland.[ncbi.nlm.nih.gov] This myopathy presented clinical and electromyographical characteristics, but unspecific histological findings.[ncbi.nlm.nih.gov]

  • Autosomal Recessive Inclusion Body Myopathy Type 2

    Symptoms of the disease usually appear between 20 and 40 years of age and include foot drop and difficulty walking.[genome.gov] Acquired myopathies can be subclassified as inflammatory myopathies, toxic myopathies, and myopathies associated with systemic conditions.[clevelandclinicmeded.com] Typically, distal weakness in the legs with foot drop is the first sign, followed by (usually) slow progression to the proximal muscles (thigh) and the upper limbs (hand muscles[orpha.net]

  • Distal Myopathy Type Welander

    Foot drop and wrist weakness may be helped by orthoses.[orpha.net] Schweizerische Medizinische Wochenschrift 97(37): 1208-1211, 1967 Welander distal myopathy is not linked to other defined distal myopathy gene loci .[eurekamag.com] Foot drop and wrist weakness may be helped by orthoses.PrognosisThe progression is benign and life expectancy is normal although the fine motor hand skills are usually lost[malacards.org]

  • Facioscapulohumeral Muscular Dystrophy

    Unusual presentations included: foot drop in 16 (13%) and proximal lower limb weakness in eight patients (7%).[ncbi.nlm.nih.gov] OBJECTIVES: To report cases of chronic autoimmune necrotizing myopathy with anti-signal recognition particle antibodies (anti-SRP myopathy) initially misdiagnosed as muscular[ncbi.nlm.nih.gov] Quadriceps and anterior tibial muscles were weak and the patient had bilateral foot drop.[ncbi.nlm.nih.gov]

  • Neurogenic Scapuloperoneal Syndrome Type Kaeser

    Symptoms - Scapuloperoneal syndrome- neurogenic- Kaeser type * Foot drop * Clubfoot * Wasting of lower leg muscles * Wasting of shoulder muscles * Leg weakness * Shoulder[checkorphan.org] […] and scapulo-peroneal myopathy.[genome.jp] At onset, bilateral foot drop and talipes equinovarus; then in a second phase, the shoulder girdle and finally bulbar involvement may occur.[whonamedit.com]

  • Muscular Dystrophy

    drop (foot dorsiflexion weakness); Weak lower abdominal muscles, protuberant abdomen; Atrophy of chest (pectoral) muscles; Curved spine (lordosis).[fshsociety.org] Nemaline myopathy Nemaline myopathy. Clusters of rod bodies. Gomori trichrome. Nemaline myopathy Nemaline myopathy. EM.[neuropathology-web.org] The selective pattern of muscle weakness in the lower limbs and back may include: foot drop due to weakness of muscles in the front of the leg weakened ability to straighten[betterhealth.vic.gov.au]

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