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624 Possible Causes for Foot Drop, Myopathy

  • Charcot Marie Tooth Disease

    Gait abnormalities reported in childhood Charcot-Marie-Tooth disease (CMT) include foot-drop, reduced ankle power at push-off and increased knee and hip flexion for swing[] 4, 5 Tropomyosin Hypertrophic cardiomyopathy 3 Nemaline myopathy 1 Titin Hypertrophic cardiomyopathy 9 Other Fibrillin Marfan syndrome Weill–Marchesani syndrome Filamin FG[] We report a 4-year-old Chinese boy with CMT symptoms including foot-drop gait, running difficulties, frequent falls, slowly progressive atrophy of lower legs with a mildly[]

  • Anterior Compartment Syndrome

    One month later, the foot drop, repeat NCS, and CT demonstrated a significant improvement with conservative management.[] […] that the condition is properly diagnosed, to rule out other conditions such as shin splints , deep vein thrombosis, nerve and vascular entrapment syndromes, infections, myopathies[] Delayed diagnosis and treatment led to extensive myonecrosis and permanent bilateral foot drop.[]

  • Muscular Dystrophy

    drop (foot dorsiflexion weakness); Weak lower abdominal muscles, protuberant abdomen; Atrophy of chest (pectoral) muscles; Curved spine (lordosis).[] Nemaline myopathy Nemaline myopathy. Clusters of rod bodies. Gomori trichrome. Nemaline myopathy Nemaline myopathy. EM.[] The selective pattern of muscle weakness in the lower limbs and back may include: foot drop due to weakness of muscles in the front of the leg weakened ability to straighten[]

  • Dermatomyositis

    drop , making it difficult to lift the front part of your foot and toes and causing the foot to drag on the ground when walking; IBM is more common in men and tends to occur[] The level of similarity between juvenile and adult myopathies regarding the presence of myositis-specific autoantibodies has not been fully elucidated.[] Dermatomyositis (DM) is inflammatory myopathy or myositis characterized by muscle weakness and skin manifestations.[]

  • Oculopharyngeal Muscular Dystrophy

    Swallowing may also be affected, and foot drop is another common late symptom. Defects in the polyadenylate binding protein gene PABPN1 are the cause of OMD.[] […] some ultrastructural characteristics with distal myopathy with rimmed vacuoles and hereditary inclusion body myopathy.[] Sometimes even foot drop is seen in such cases. Muscles of abdomen, lower arm, triceps, biceps and deltoids are weak.[]

  • Central Core Disease

    Drop 386 Case 61 An Elderly Woman with Foot Drop and Hand Weakness 393 Case 62 A Woman with Rheumatoid Arthritis Who Developed Numbness and Pain in the Feet 399 Case 63 A[] This review will focus on myotubular myopathy, centronuclear myopathy, central core disease, and congenital neuromuscular disease with uniform Type 1 fiber, myopathies that[] drop; affected muscles almost always lack reflexes Myotonia congenita: voluntary muscles of the arms, legs, and face are stiff or slow to relax after contracting (myotonia[]

  • Intramuscular Injection

    A 25-year-old male patient presented with foot drop indicative of a sciatic nerve injury following gluteal intramuscular (IM) injections.[] We report a patient in whom chronic intramuscular piritramide led to a focal fibrotic myopathy.[] Despite this, there have been reports of injuries to the sciatic nerve leading to problems ranging from foot drop to paralysis of the lower limb.[]

  • Facioscapulohumeral Muscular Dystrophy

    FSHD presentation with foot drop or lower limb proximal weakness appeared to be more frequent than expected.[] To report cases of chronic autoimmune necrotizing myopathy with anti-signal recognition particle antibodies (anti-SRP myopathy) initially misdiagnosed as muscular dystrophy[] Quadriceps and anterior tibial muscles were weak and the patient had bilateral foot drop.[]

  • Becker Muscular Dystrophy

    These signs include: trouble walking difficulty raising the front of their foot (called foot drop ) falling Over time, children with muscular dystrophy can become weaker and[] In a boy with myopathy and an increase of muscle fibres with central nuclei we detected a heterozygous 387G-- T nucleotide transversion in the MYF6 gene (MIM*159991).[] Serum was assayed from patients with Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), inclusion body myositis (IBM), and GNE myopathy (GNE).[]

  • Polymyositis

    Foot drop in one or both feet can be a symptom of advanced polymyositis and inclusion body myositis .[] Furthermore, glucocorticosteroid (GC) toxicity leads to a significant disability known as steroid myopathy, particularly in elderly patients.[] drop – during advanced stages Rash predominantly on the shoulders, chest and back – the shawl region, in dermatomyositis.[]

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