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13 Possible Causes for Foot Drop, Severe Peripheral Motor Neuropathy, Unilateral Arm Weakness

  • Multifocal Motor Neuropathy

    Clinically, it is characterized by slowly progressive asymmetrical predominantly distal weakness; unilateral wrist drop, grip weakness, and foot drop are the commonest initial[ncbi.nlm.nih.gov] An autopsy showed severe widespread demyelination without lymphoma cell infiltration in the peripheral nerves.[ncbi.nlm.nih.gov] Wrist drop and foot drop (leading to trips and falls) are common symptoms. Other effects can include gradual loss of finger extension, leading to a clawlike appearance.[en.wikipedia.org]

  • Mononeuritis Multiplex

    Mononeuritis multiplex is a peripheral sensorimotor neuropathy usually producing foot or wrist drop, commonly associated with necrotizing arteritis of small and medium-sized[ncbi.nlm.nih.gov] […] and motor peripheral neuropathy involving simultaneous or sequential damage to two or more noncontiguous peripheral nerves .  : Bradely’s neurology in clinical practice 7th[slideshare.net] drop.[ncbi.nlm.nih.gov]

  • Brachial Plexus Neuropathy

    The physicians at the Center also perform Bell’s palsy treatment, radial, median, and ulnar nerve surgery, foot drop treatment, and an entire range of other nerve reconstruction[advancedreconstruction.com] CIDP It is an acquired, immune-mediated peripheral neuropathy, presents with relapsing and remitting motor and sensory loss in multiple limbs [ 30 ].[omicsonline.org] Onset age Median 3 years Range 3 days to 15 years Weakness Acute onset Unilateral Arm Proximal & Distal Pain (50%) Osteomyelitis Shoulder or Humerus Newborns Onset: After[neuromuscular.wustl.edu]

  • Diabetic Mononeuropathy

    Distribution: Common areas effected Wrist Drop ( Radial Nerve ) Loss of finger flexion and grip ( Median Nerve ) Foot drop (deep peroneal nerve, L4-L5) Recurrent laryngeal[fpnotebook.com] Autopsy studies on several patients showed peripheral nerve degeneration ( Leyden 1887 ; Auche 1890 ).[medlink.com] Arms: Upper, Middle & Lower Brachial plexus segments Other body parts (60%) Opposite arm Lumbosacral Thoracic Weakness (98%) Pain (80%) Numbness (70%) Course Often monophasic[neuromuscular.wustl.edu]

  • Diabetic Enteropathy

    […] care Glucose control Pain control Single nerve damage due to compression or ischemia Occurs in wrist (carpal tunnel syndrome), elbow, or foot (unilateral foot drop) Symptoms[quizlet.com] Peripheral sensori-motor neuropathy  Distal, bilateral,symmetrical, stocking-glove distribution.  Symptoms range from numbness (“deadness”) to severe pain.[slideshare.net] Arms: Upper, Middle & Lower Brachial plexus segments Other body parts (60%) Opposite arm Lumbosacral Thoracic Weakness (98%) Pain (80%) Numbness (70%) Course Often monophasic[neuromuscular.wustl.edu]

  • Diabetic Amyotrophy

    Design/Methods: A 62 year old with history of diabetes mellitus-II presented with 2 weeks history of right foot drop and back pain radiating down into right lateral thigh,[n.neurology.org] It includes several variants: Acute inflammatory demyelinative polyneuropathy (AIDP), acute motor axonal neuropathy (AMAN), and the Miller-Fisher syndrome (MFS).[neuropathology-web.org] Only five patients displayed asymmetric proximal lower limb wasting, weakness and pain, motor deficits in the remainder being either unilateral or bilateral and symmetrical[ncbi.nlm.nih.gov]

  • Autosomal Recessive Lower Motor Neuron Disease with Childhood Onset

    The leg weakness frequently causes “foot drop” and a waddling gait.[britannica.com] Several subtypes of inherited peripheral neuropathies were delineated and classified as hereditary motor and sensory neuropathies (HMSN), hereditary motor neuropathies (HMN[molgen.ua.ac.be] Ipsilateral distal arm contralateral proximal arm, weakness in 4 patients, leg affected in 1 pt 20–40 Unilateral scapulohumeral muscular atrophy Katz et al . 1999 10 6:4[academic.oup.com]

  • Diabetic Neuropathy

    This is otherwise known as diabetic drop foot.[podiatrytoday.com] Diabetic neuropathy affects all peripheral nerves including sensory neurons, motor neurons, but rarely affects the autonomic nervous system.[en.wikipedia.org] Arms: Upper, Middle & Lower Brachial plexus segments Other body parts (60%) Opposite arm Lumbosacral Thoracic Weakness (98%) Pain (80%) Numbness (70%) Course Often monophasic[neuromuscular.wustl.edu]

  • Diabetic Polyneuropathy

    Unilateral foot drop occurs when the foot can't be picked up because a nerve in the leg has been damaged either by blood vessel disease or compression.[joslin.org] Signs and symptoms [ edit ] Illustration depicting areas affected by diabetic neuropathy Diabetic neuropathy affects all peripheral nerves including sensory neurons, motor[en.wikipedia.org] Arms: Upper, Middle & Lower Brachial plexus segments Other body parts (60%) Opposite arm Lumbosacral Thoracic Weakness (98%) Pain (80%) Numbness (70%) Course Often monophasic[neuromuscular.wustl.edu]

  • Monomelic Amyotrophy

    Drop 386 Case 61 An Elderly Woman with Foot Drop and Hand Weakness 393 Case 62 A Woman with Rheumatoid Arthritis Who Developed Numbness and Pain in the Feet 399 Case 63 A[books.google.com] Signs and symptoms initially progressed, but spontaneously arrested after several years. Upper motor neuron, sensory, and sphincteric symptoms and signs remained absent.[ahcmedia.com] A 28-year-old white man presented with insidious-onset, slowly progressive, unilateral weakness and atrophy of his left shoulder girdle and deltoid muscles.[ncbi.nlm.nih.gov]

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