Formication: Causes & Reasons

Possible Causes for Formication

Central nervous system manifestations are as follows: Change of mental status, disorientation, and headache Dyskinesias Agitation Formication Symptoms of stroke Cardiovascular [emedicine.medscape.com]

Formication (sensory hallucination of insects crawling on/under skin, leading to obsessive scratching) and ulceration. [patient.info]

Confusion or agitation Bruxism Stroke caused by acute amphetamine toxicity Cutaneous findings are as follows: Skin flushing Infected deep ulcerations (ecthyma) in patients with formication [emedicine.medscape.com]

Vitamin B12 Deficiency

Vitamin B12 (cobalamin) deficiency is common in developing countries. Its dermatologic manifestations include hair and nail changes and glossitis. Cases of generalized hyperpigmentation associated with vitamin B12 deficiency have rarely been reported. Localized hyperpigmentation is less frequently described, affecting[…] [ncbi.nlm.nih.gov]

Anxiety Disorder

PURPOSE: To evaluate the differential gray matter (GM) and white matter volume alterations between healthy controls and patients with obsessive-compulsive disorder (OCD) and generalized anxiety disorder (GAD) using voxel-based morphometry (VBM). METHOD: Patients with OCD and GAD, and healthy controls underwent[…] [ncbi.nlm.nih.gov]

Primary Progressive Multiple Sclerosis

We present three patients with a clinical course and cerebrospinal fluid findings consistent with a diagnosis of primary progressive multiple sclerosis (PPMS). Extensive and repeated magnetic resonance imaging (MRI) examinations showed only diffuse abnormality in brain and spinal cord, but no focal lesions. We propose[…] [ncbi.nlm.nih.gov]

Urtica Dioica

The fresh leaves cause wheals due to the formic acid is the nettle hairs. [thenaturopathicherbalist.com]

This is probably due to the action of formic acid upon nitrates (E. Giustianini, Jahresb. der Pharm ., 1896, p. 239). Action, Medical Uses, and Dosage. [henriettes-herb.com]

These small hollow spines pierce human skin and inject small amounts of formic acid. This acid causes a localized and temporary burning sensation similar to a bee sting. [oregonstate.edu]

Lyme Neuroborreliosis

A positive antibody response may lead to more confusion than clarification. Borrelia bacteria can be transmitted to humans through tick bites and give rise to Lyme neuroborreliosis. Disease manifestation varies in terms of symptoms and time course. Most patients experience subacute onset of neurological symptoms[…] [tidsskriftet.no]

Multiple Sclerosis

Dr. Carla Rossotti (left), a general practitioner, and her health care team leave the home of the their patient, 37-year-old Osvaldo Daniel Martinez. He has the symptoms of a degenerative disease, Rossotti says, but he needs a neurologist's evaluation before he can get proper treatment. Sarah Varney/Kaiser Health[…] [npr.org]

Amphetamine Delusional Disorder

Misdiagnosed Pruritus; Formication due to Chronic Amphetamine Abuse. Asia Pac J Med Toxicol 2016;5:32-4. Statistics Article View: 1,399 PDF Download: 779 [apjmt.mums.ac.ir]

In some cases, formication occurs during active use of a given substance; in other cases, it occurs during withdrawal from a substance. [addiction.com]

Instant Feedback: Formication is a tactile hallucination. [rnceus.com]

Chronic Myeloid Leukemia

Chronic myeloid leukemia: reminiscences and dreams, Jerald P. Radich, Michael W. Deininger, Jane F. Apperley, Timothy P. Hughes, Christine J. Harrison, Carlo Gambacorti-Passerini, Giuseppe Saglio, Jorge Cortes, George Q. Daley Haematologica May 2016 101: 541-558; doi: 10.3324/haematol.2015.139337 Abstract With the deaths of[…] [haematologica.org]

Hypoparathyroidism

[…] noun mass noun Medicine Diminished concentration of parathyroid hormone in the blood, which causes deficiencies of calcium and phosphorus compounds in the blood and results in muscular spasms. ‘Risks of parathyroid surgery include permanent hypoparathyroidism and damage to the recurrent laryngeal nerve.’[…] [en.oxforddictionaries.com]

Essential Thrombocythemia

Review Open Access Published: 08 January 2007 Orphanet Journal of Rare Diseases volume 2, Article number: 3 (2007) Cite this article 30k Accesses 57 Citations 9 Altmetric Metrics details Abstract Essential thrombocythemia (ET) is an acquired myeloproliferative disorder (MPD) characterized by a sustained elevation[…] [ojrd.biomedcentral.com]

Erythropoietic Protoporphyria

EPP Patient Day The American Porphyria Foundation and the Canadian Association for Porphyria Present - EPP Patient Day - featuring Porphyria Expert Dr. Karl Saardi with Q&A Session, Youngster and Adult Patient Presentations, and a VERY SPECIAL ANNOUNCEMENT for ALL EPP Patients!! You will not want to miss this[…] [porphyriafoundation.org]

Hereditary ATTR Amyloidosis

Transthyretin amyloid neuropathy, Amyloidosis Transthyretin related, ATTR, Neuropathic heredofamilail amyloidosis, FAP, Familial amyloidotic neuropathies, Transthyretin-related hereditary amyloidosis, Transthyretin amyloidosis, Corino de Andrade's disease, Familial amyloid neuropathies, Familial transthyretin amyloidosis, TTR[…] [checkorphan.org]

Croton Oil Poisoning

It contains fatty acids like oleic acid, linoleic acid, myristic acid, arachidic acid, palmitic acid, formic acid, acetic acid, stearic acid, and less amounts of butyric acid [buzzle.com]

Of the acids, 37.0% is oleic, 19.0% linoleic, 1.5% arachidic, 0.3% stearic, 0.9% palmitic, 7.5% myristic, 0.6% acetic, 0.8% formic, with traces of lauric, tiglic, valeric, [hort.purdue.edu]

The oil comprises the fatty acids oleic acid 37%, linoleic acid 19%, myristic acid 7.5%, arachidic acid 1.5%, palmitic acid 1%, formic acid 1%, acetic acid 0.5%, stearic acid [tropical.theferns.info]

Methanol Poisoning

The role of formic acid in methanol toxicity in human subjects has not been established. [ncbi.nlm.nih.gov]

Occupational exposure to vapours of methanol and formic acid can be quantitatively monitored by urinary formic acid determinations. [doi.org]

A sensitive and specific assay was used to measure formic acid levels in blood and other fluids. [ncbi.nlm.nih.gov]

Methyl Ethyl Ketone Poisoning

Propionic acid and formic acid were not measurable at any time. [tandfonline.com]

Sigurdsson J, Björnsson A, Gudmundsson ST (1983) Formic acid burn--local and systemic effects. Report of a case.BurnsInclThermInj 9: 358-361. [omicsonline.org]

Finally, during MEKP decay, various organic acids are formed, e.g. formic acid, which induce acidosis and optic neuropathy. [flore.unifi.it]

Metaldehyde Poisoning

This objective was achieved by adding acidified water (0.1% formic acid) to the methanol spray solvent MeOH:(H 2 O + 0.1% formic acid) (1:1, v/v). [nature.com]

The resultant PS-MS mass spectrum recorded when 5 μg of metaldehyde in 1 μL of deionized water was deposited on the paper substrate using MeOH:(H 2 O + 0.1% formic acid) [nature.com]

This quantitative analysis of metaldehyde in water was achieved from the metaldehyde calibration curve obtained with PS-MS using MeOH:(H 2 O + 0.1% formic acid) (1:1, v/v) [nature.com]

Chemical Burn

We report on a 26-year-old woman who during early infancy (6 months) suffered from a chemical burn of the skin and upper airways due to spill of formic acid powder. [ncbi.nlm.nih.gov]

[…] acid burn 11719311 - Formic acid burn 11719308 - Chemical burns 11719306 - Chemical burns 11684175 - Detergent burn to child's eye 11672832 - Mustard gas burns,War War I [sciencephoto.fr]

The pharmacist should be closely involved when burns are caused by medications like podophyllotoxin, formic acid or topical salicylic acid. [statpearls.com]

Acidifying Agent Poisoning

The eluent consisted of solvent A (0.2% v/v formic acid in water) and solvent B (0.2% v/v formic acid in acetonitrile). [link.springer.com]

[…] acid which is toxic to the optic nerve early toxicity of formic acid is metabolic acidosis by formic acid itself formic acid also binds to cytochrome oxidase blocking oxidative [medbullets.com]

Sulfite or Potassium Bisulphite, Potassium Hydrogen Sulphite preservatives H A – E230 Diphenyl, Biphenyl preservatives – – C E231 Orthophenyl Phenol preservatives – – C E236 Formic [traditionaloven.com]

Toxic Effect of Corrosive Substances

[…] acid 10% Slow decomposing effect Formic acid 30% Slow decomposing effect Hydrogen chloride 10% Quick corrosive effect, also on steel Hydrogen chloride 37% Quick corrosive [training.itcilo.it]

Some concentrated weak acids, for example formic acid and acetic acid Strong Lewis acids such as anhydrous aluminum chloride and boron trifluoride Lewis acids with specific [en.wikipedia.org]

8 IB2, T7, TP21542022421 L30 L A 40 Formic acid with not less than 5% but not more than 10% acid by mass 8 UN3412III 8 IB3, T4, TP11542032415 L60 L A 40 Fuel cell cartridges [environmentalchemistry.com]

Toxic Effect of Corrosive Alkalis

There are two types of acids: mineral (inorganic) acids—such as sulfuric, hydrochloric, or nitric—and carboxylic (organic) acids such as formic or acetic. [labmanager.com]

[…] acid 10% Slow decomposing effect Formic acid 30% Slow decomposing effect Hydrogen chloride 10% Quick corrosive effect, also on steel Hydrogen chloride 37% Quick corrosive [training.itcilo.it]

Some concentrated weak acids, for example formic acid and acetic acid Strong Lewis acids such as anhydrous aluminum chloride and boron trifluoride Lewis acids with specific [en.wikipedia.org]

Organic Delusional Disorder

In some cases, formication occurs during active use of a given substance; in other cases, it occurs during withdrawal from a substance. [addiction.com]

Classically, patients complain of scratching, biting, burrowing, and wriggling sensations under the skin (formication). [dovepress.com]

Very often the imaginary parasites are reported as being "bugs" or insects crawling on or under the skin; in these cases the experience of the sensation known as formication [delusionalinsects.com]

Isopropyl Alcohol Poisoning

High anion gap metabolic acidosis (HAGMA) is produced due to generation of formic acid and increased production of lactic acid. [lifeinthefastlane.com]

Toxic effects are due in part to the alcohol itself, and in part to formic acid produced by its oxidation. [merckvetmanual.com]

The toxicity with methanol occurs from both the ensuing metabolic acidosis, as well as the formate anion (formic acid) itself. [17] Although the eye is the primary site of [emedicine.medscape.com]

Toxic Effect of Glycols

The formic acid buildup and lactic acid buildup are to thank for this. [emdocs.net]

An additional benefit is the effect of "ion trapping" formic acid. [derangedphysiology.com]

The formaldehyde is then metabolized by aldehyde dehydrogenase to formic acid. [emdocs.net]

Toxic Gastritis

High anion gap metabolic acidosis (HAGMA) is produced due to generation of formic acid and increased production of lactic acid. [lifeinthefastlane.com]

Methanol is metabolized into formaldehyde and formic acid, which can accumulate in the retina causing edema and optic papillitis. [epmonthly.com]

Formic acid is the main toxic metabolite responsible for the retinal, ophthalmic and neural toxicity seen with methanol ingestion. [lifeinthefastlane.com]

Formaldehyde Poisoning

Methanol, formaldehyde, and formic acid levels in the blood of the patient are reported following the ingestion of formaldehyde solution. [jamanetwork.com]

Metabolic (anion gap) acidosis may be caused by formic acid accumulation from metabolism of formaldehyde or methanol. [accessmedicine.mhmedical.com]

It is metabolized to formic acid in liver and blood Route : Ingestion and inhalation Mechanism of action : • Inhalation: burning of eyes, lacrymaton, coughing, constriction [pediatriconcall.com]

Citrulline Transport Defect

The mobile phase was composed of (A) water (0.1% formic acid v/v) and (B) acetonitrile (0.1% formic acid v/v). [ncbi.nlm.nih.gov]

Pagon Stephan Syndrome

1943) EponymGenetics Ekbom syndrome II Stephen Whelan and Mike Cadogan November 3, 2020 Ekbom syndrome or delusional parasitosis is characterised by delusions, symptoms of formication [litfl.com]

Fucosyltransferase 6 Deficiency

Subsequently, 25 μl of formic acid was then added to each tube and homogenized by vortex, followed by the addition of 25 μl of acetonitrile. [microbiomejournal.biomedcentral.com]

[…] acid in water as aqueous solvent A and 90% acetonitrile and 0.1% formic acid in water as organic solvent B (gradient also described previously). [microbiomejournal.biomedcentral.com]

[…] and loaded onto the enrichment column and subsequently separated on the analytical column with a gradient optimized for glycan separation, using 3% acetonitrile and 0.1% formic [microbiomejournal.biomedcentral.com]

Insect Bite

Many species of bees and wasps have two poison glands, one gland secreting a toxin in which formic acid is one recognized constituent, and the other secreting an alkaline [britannica.com]

Some insects inject formic acid, which can cause an immediate skin reaction often resulting in redness and swelling in the injured area. [en.wikipedia.org]

Formic acid, a component of ant venom uncommon in bee or wasp stings, is derived from the superfamily name Formicidae. [emedicine.medscape.com]