Formication: Causes & Reasons

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Possible Causes for Formication

Vitamin B12 Deficiency

1. Lindenbaum, J, Rosenberg, IH, Wilson, PWF, Stabler, SP, Allen, RH. Prevalence of cobalamin deficiency in the Framingham elderly population. Am J Clin Nutr 1994 ;60: 2 – 11. Google Scholar Crossref Medline ISI 2. Bethell, FH, Castle, WB, Conley, CL, London, IM. Present status of treatment of pernicious anemia: Ninth[…] [doi.org]

Acute Amphetamine Intoxication

Central nervous system manifestations are as follows: Change of mental status, disorientation, and headache Dyskinesias Agitation Formication Symptoms of stroke Cardiovascular [emedicine.medscape.com]

Formication (sensory hallucination of insects crawling on/under skin, leading to obsessive scratching) and ulceration. [patient.info]

Confusion or agitation Bruxism Stroke caused by acute amphetamine toxicity Cutaneous findings are as follows: Skin flushing Infected deep ulcerations (ecthyma) in patients with formication [emedicine.medscape.com]

Anxiety Disorder

From Wikidata Jump to navigation Jump to search cognitive disorder with an excessive, irrational dread of everyday situations anxiety state anxiety neurosis chronic anxiety anxiety edit English anxiety disorder cognitive disorder with an excessive, irrational dread of everyday situations anxiety state anxiety[…] [wikidata.org]

Primary Progressive Multiple Sclerosis

We present three patients with a clinical course and cerebrospinal fluid findings consistent with a diagnosis of primary progressive multiple sclerosis (PPMS). Extensive and repeated magnetic resonance imaging (MRI) examinations showed only diffuse abnormality in brain and spinal cord, but no focal lesions. We propose[…] [ncbi.nlm.nih.gov]

Insect Bite

Some insects inject formic acid, which can cause an immediate skin reaction often resulting in redness and swelling in the injured area. [en.wikipedia.org]

Many species of bees and wasps have two poison glands, one gland secreting a toxin in which formic acid is one recognized constituent, and the other secreting an alkaline [britannica.com]

Some insect bites contain an acid substance resembling formic acid and consequently are relieved by topically applied alkalies, such as ammonia water or baking soda paste. [medical-dictionary.thefreedictionary.com]

Lyme Neuroborreliosis

A 36-year-old Japanese woman presented with progressive cerebellar signs and mental deterioration of subacute course after her return from the USA. Her serum antibody to spirochete Borrelia burgdorferi was significantly elevated. A necropsy 4 years after her initial neurological signs revealed multifocal[…] [ncbi.nlm.nih.gov]

Multiple Sclerosis

Mult Scler. 2017 Mar;23(3):483-486. doi: 10.1177/1352458516678475. Epub 2016 Nov 12. Author information 1 Department of Neurology, St. Josef Hospital, Ruhr-University of Bochum, Bochum, Germany. 2 Institute of Diagnostic and Interventional Radiology, St. Josef Hospital, Ruhr-University of Bochum, Bochum, Germany.[…] [ncbi.nlm.nih.gov]

Chronic Myeloid Leukemia

Summary Epidemiology Its annual incidence has been estimated at between 1 and 1.5 cases per 100,000 and its prevalence at around 1 in 17,000. Clinical description The disease is typically triphasic with a chronic phase (CML-CP), accelerated phase (CML-AP) and blast phase (CML-BP). The majority of patients are[…] [orpha.net]

Hypoparathyroidism

OBJECTIVE: Hypocalcaemia is the most common adverse effect after total thyroidectomy. It recovers in about two-thirds of the patients within the first postoperative month. Little is known, however, about recovery of the parathyroid function (RPF) after this time period. The aim of the present study was to[…] [ncbi.nlm.nih.gov]

Essential Thrombocythemia

Thromb Res. 2017 Aug;156:168-171. doi: 10.1016/j.thromres.2017.06.023. Epub 2017 Jun 21. Latagliata R 1, Montanaro M 2, Cedrone M 2, Di Veroli A 2, Spirito F 2, Santoro C 2, Leonetti Crescenzi S 2, Porrini R 2, Di Giandomenico J 2, Villivà N 2, Spadea A 2, Rago A 2, De Gregoris C 2, Romano A 2, Anaclerico B 2, De Muro M 2,[…] [ncbi.nlm.nih.gov]

Erythropoietic Protoporphyria

The porphyrias are a group of rare metabolic disorders that result from defects in heme biosynthesis. Erythropoietic protoporphyria (EPP) is the most common inherited porphyria in children and is diagnosed in most individuals after the onset of cutaneous manifestations. Hepatobiliary disease affects the minority[…] [ncbi.nlm.nih.gov]

Amphetamine Delusional Disorder

Misdiagnosed Pruritus; Formication due to Chronic Amphetamine Abuse. Asia Pac J Med Toxicol 2016;5:32-4. Statistics Article View: 1,399 PDF Download: 779 [apjmt.mums.ac.ir]

In some cases, formication occurs during active use of a given substance; in other cases, it occurs during withdrawal from a substance. [addiction.com]

Instant Feedback: Formication is a tactile hallucination. [rnceus.com]

Hereditary ATTR Amyloidosis

History The subtype of transthyretin (TTR) protein mutation, its tissue distribution, and the amount of amyloid deposition largely determine the clinical manifestations of TTR-related amyloidosis (ATTR). The key characteristic of ATTR that should raise clinical suspicion for this disorder remains the reliable[…] [emedicine.medscape.com]

Methanol Poisoning

The role of formic acid in methanol toxicity in human subjects has not been established. [ncbi.nlm.nih.gov]

Occupational exposure to vapours of methanol and formic acid can be quantitatively monitored by urinary formic acid determinations. [doi.org]

A sensitive and specific assay was used to measure formic acid levels in blood and other fluids. [ncbi.nlm.nih.gov]

Chemical Burn

We report on a 26-year-old woman who during early infancy (6 months) suffered from a chemical burn of the skin and upper airways due to spill of formic acid powder. [ncbi.nlm.nih.gov]

Formic acid is used in the tanning industry as well as in glue making. It creates a deep eschar that does not protect the body from systemic effects. [autoaccident.com]

The pharmacist should be closely involved when burns are caused by medications like podophyllotoxin, formic acid or topical salicylic acid. [statpearls.com]

Metaldehyde Poisoning

This objective was achieved by adding acidified water (0.1% formic acid) to the methanol spray solvent MeOH:(H 2 O 0.1% formic acid) (1:1, v/v). [nature.com]

The resultant PS-MS mass spectrum recorded when 5 μg of metaldehyde in 1 μL of deionized water was deposited on the paper substrate using MeOH:(H 2 O 0.1% formic acid) [nature.com]

This quantitative analysis of metaldehyde in water was achieved from the metaldehyde calibration curve obtained with PS-MS using MeOH:(H 2 O 0.1% formic acid) (1:1, v/v) [nature.com]

Croton Oil Poisoning

It contains fatty acids like oleic acid, linoleic acid, myristic acid, arachidic acid, palmitic acid, formic acid, acetic acid, stearic acid, and less amounts of butyric acid [buzzle.com]

contains glycerides of stearic, palmitic, myristic, lauric, and oleic acids, and of the volatile acids - acetic, butyric, formic, valeric, tiglic (tiglinic - oleic series [chestofbooks.com]

The oil comprises the fatty acids oleic acid 37%, linoleic acid 19%, myristic acid 7.5%, arachidic acid 1.5%, palmitic acid 1%, formic acid 1%, acetic acid 0.5%, stearic acid [tropical.theferns.info]

Acidosis

[…] arbonic anhydrase inhibitors A A ddisons (Type 4 RTA) R R enal tubular acidosis types 1, 2, and 4 P P ancreatic fistula Increased anion gap metabolic acidosis M M ethanol (formic [lifeinthefastlane.com]

Formic acid and formaldehyde are the toxic metabolites that interfere with oxidative phosphorylation. [clinicaladvisor.com]

The final metabolite of methanol (formic acid) is highly toxic to the retina, and can lead to permanent blindness. [renalandurologynews.com]

Acute Alcohol Intoxication

This pathway is easily saturable, contributing to accumulation of formic acid in the blood. [cjasn.asnjournals.org]

In addition, when the patient is not acidotic, formic acid dissociates to formate at lower rates so that less formate crosses the blood-brain barrier. [emedicine.medscape.com]

Formic acid is the metabolite responsible for acidosis and end organ injury following methanol ingestion. [clinicaladvisor.com]

Organic Delusional Disorder

In some cases, formication occurs during active use of a given substance; in other cases, it occurs during withdrawal from a substance. [addiction.com]

Classically, patients complain of scratching, biting, burrowing, and wriggling sensations under the skin (formication). [dovepress.com]

Very often the imaginary parasites are reported as being "bugs" or insects crawling on or under the skin; in these cases the experience of the sensation known as formication [delusionalinsects.com]

Methyl Ethyl Ketone Poisoning

formic acid, acetic acid, propionic acid). [omicsonline.org]

Finally, during MEKP decay, various organic acids are formed, e.g. formic acid, which induce acidosis and optic neuropathy. [flore.unifi.it]

Sigurdsson J, Björnsson A, Gudmundsson ST (1983) Formic acid burn--local and systemic effects. Report of a case.BurnsInclThermInj 9: 358-361. [omicsonline.org]

Ophthalmia Nodosa

It has been demonstrated by Karsten that the canal of the hairs carries formic acid [jamanetwork.com]

Gingivitis

For tau (1:20,000; rabbit A0024, DAKO), IHC slides were immersed in 99% formic acid for 5 min, rinsed three times in milliQH 2 O, and then treated as per other slides. [doi.org]

Bacteria were immersed in 4% paraformaldehyde for 10 min, washed three times in PBS, and incubated in formic acid for 7 min, followed by another three washes with PBS. [doi.org]

Peptides were separated by a linear gradient from 95% buffer A [0.1% formic acid (FA) in water]/5% buffer B [0.1% FA in acetonitrile (ACN)] to 60% buffer A/40% buffer B over [doi.org]

Toxic Effect of Corrosive Substances

[…] acid 10% Slow decomposing effect Formic acid 30% Slow decomposing effect Hydrogen chloride 10% Quick corrosive effect, also on steel Hydrogen chloride 37% Quick corrosive [training.itcilo.it]

Some concentrated weak acids, for example formic acid and acetic acid Strong Lewis acids such as anhydrous aluminum chloride and boron trifluoride Lewis acids with specific [en.wikipedia.org]

8 IB2, T7, TP21542022421 L30 L A 40 Formic acid with not less than 5% but not more than 10% acid by mass 8 UN3412III 8 IB3, T4, TP11542032415 L60 L A 40 Fuel cell cartridges [environmentalchemistry.com]

Toxic Effect of Corrosive Alkalis

There are two types of acids: mineral (inorganic) acids—such as sulfuric, hydrochloric, or nitric—and carboxylic (organic) acids such as formic or acetic. [labmanager.com]

[…] acid 10% Slow decomposing effect Formic acid 30% Slow decomposing effect Hydrogen chloride 10% Quick corrosive effect, also on steel Hydrogen chloride 37% Quick corrosive [training.itcilo.it]

Some concentrated weak acids, for example formic acid and acetic acid Strong Lewis acids such as anhydrous aluminum chloride and boron trifluoride Lewis acids with specific [en.wikipedia.org]

Stomatitis

[…] therapeutic active constituents, comprising nitrogenous substances (proteins and amino acids), sugars, fat, phytosterols, an essential oil rich in ketones, aldehydes and acids, formic [prodecopharma.com]

Acidifying Agent Poisoning

The eluent consisted of solvent A (0.2% v/v formic acid in water) and solvent B (0.2% v/v formic acid in acetonitrile). [link.springer.com]

[…] acid which is toxic to the optic nerve early toxicity of formic acid is metabolic acidosis by formic acid itself formic acid also binds to cytochrome oxidase blocking oxidative [medbullets.com]

Sulfite or Potassium Bisulphite, Potassium Hydrogen Sulphite preservatives H A – E230 Diphenyl, Biphenyl preservatives – – C E231 Orthophenyl Phenol preservatives – – C E236 Formic [traditionaloven.com]

Bee Sting

The action of venom is much more complex than the simple concept of direct action on the tissue by formic acid. [beesource.com]

The facts are that: Bee venom contains formic acid (also known as methanoic acid) but this is not the single active ingredient that causes the pain from a bee sting Wasp stings [insectstings.co.uk]

Formic acid, a component of ant venom uncommon in bee or wasp stings, is derived from the superfamily name Formicidae. [emedicine.medscape.com]

Alcohol Abuse

Hcy, acetonitrile, formic acid (Sigma), and dl- [ 2 H 4 ]Hcy (Cambridge Isotopes Laboratories) were utilized as standards. [doi.org]

The plasma samples were washed with 1 ml of 1% formic acid and 1 ml of methanol, and the compounds were eluted with 1 ml of 5% ammonium hydroxide. [doi.org]

Dermatitis

Symptoms include itching, a pinprick sensation, and, less commonly, formications. [doi.org]

See also[edit] Formication, a sensation that resembles that of small insects crawling on or under the skin Pruritus ani (also known as anusitis), irritation of skin at the [en.wikipedia.org]