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174 Possible Causes for Foveal Atrophy

  • Cone Dystrophy with Supernormal Rod Response

    Macular defects ranging from mild pigmentary changes to distinct foveal atrophy were present in nine patients.[] M 17, 36 0.12 5.25 Yes Yes No Slight foveal atrophy Yes 0.12 5.00 14592_IM D339_V341del D339_V341del M 50 0.1 1.50–1.50 135 No Yes No Distinct foveal RPE atrophy ND 0.1 2.50[] The fundus appears normal in some patients but foveal or parafoveal atrophy, a macular bull’s eye, hyperfluorescence anomalies, and a generalized fine pigmentary retinopathy[]

  • Retinal Telangiectasia

    Fluorescein angiography found no active leakage, and optical coherence tomography found significant foveal atrophy.[] Severity 3: Moderate to marked foveal hyperautofluorescence with angiographic abnormalities and foveal atrophy documented on optical coherence tomography.[] Nonproliferative perifoveal telangiectasia refers to exudative telangiectasia and foveal atrophy.[]

  • Stargardt Disease

    In 14 out of 50 patients, foveal atrophy occurred before flecks developed.[] There was a higher prevalence of the variant p.Arg2030Gln in the cohort with foveal sparing compared to the group with foveal atrophy (6.45% vs 1.07%).[] RPE atrophy ( asterisks ) was graded as ( B ) none, ( C ) extrafoveal (but not fovea encircling), ( D ) foveal sparing ( 180 encircling the fovea), or ( F ) central RPE atrophy[]

  • Macular Dystrophy with Central Cone Involvement

    These patients develop foveal atrophy that may be misdiagnosed as Stargardt disease, but the ERG shows severely abnormal photopic responses, whereas the scotopic response[] The grandfather (II:1) had partial foveal atrophy, with a hyporeflective zone in both eyes.[] […] juvenile-onset foveal atrophy surrounded by discrete, yellowish, round or pisciform flecks at the level of the RPE (Fig 12-7A).[]

  • Central Areolar Choroidal Dystrophy

    atrophy surrounded by disciform flecks at the level of the retinal pigment epithelium.[] This indicates that choriocapillaris atrophy is an early finding in this disease.[] […] corresponding to the location of the retinal and retinal pigment epithelium atrophy.[]

  • Vitreoretinochoroidopathy

    RESULTS: Long-term follow up of the first ever reported ADVIRC proband revealed progressive foveal atrophy in both eyes 3 decades after his initial presentation.[] Fundus autofluorescence photography reveals hypoautofluorescence in the area of foveal retinal pigment epithelial atrophy and mild hyperautofluorescence in the superior, nasal[] At age 79, fundus autofluorescence photography demonstrates hypoautofluorescence in the areas of perifoveal retinal pigment epithelial atrophy with hyperautofluorescence in[]

  • Achromatopsia

    The younger patients had absent to mild foveal atrophy on OCT, and four of the six demonstrated foveal and parafoveal hyperfluorescence on FAF.[] […] in 8.9% of all cases and foveal hypoplasia in 29 patients (85%).[] Foveal and outer nuclear layer (ONL) thickness was measured and presence of hypoplasia determined.[]

  • Sjogren-Larsson Syndrome

    […] spaces to cystoid foveal atrophy.[] CONCLUSIONS: Patients with SLS show a childhood-onset crystalline macular dystrophy with cystoid foveal atrophy on OCT in most cases.[] More interestingly, a cystoid foveal degeneration on OCT was present in the majority of patients with SLS (18/27 eyes, or 67% of all eyes studied), varying from multiple microcystoid[]

  • Foveal Hypoplasia - Presenile Cataract Syndrome

    Congenital anomaly of eye Congenital nystagmus Foveal hypoplasia Nystagmus Optic atrophy Presenile cataracts Visual impairment Back to: « Foveal hypoplasia Genetics of Foveal[] […] pigmentation and sheathing, retinal thinning, as well as slowly progressive chorioretinal atrophy.[] Symptoms of Foveal hypoplasia and presenile cataract syndrome Clinical features : Imported from Human Phenotype Ontology (HPO) Abnormality of the integument Generalized hyperpigmentation[]

  • X-Linked Cone Rod Dystrophy

    These patients develop foveal atrophy that may be misdiagnosed as Stargardt disease, but the ERG shows severely abnormal photopic responses, whereas the scotopic response[] […] increased foveal in areas of atrophy AF; reduced AF in areas of atrophy severely reduced or undetectable reduced cone and rod responses; * “negative ERG” Peripherin (AD)[] […] flash and flicker with minimal or no 30Hz flicker implicit time shift; in CORD, additional reduction in rod responses GUCY2D (AD) 1st, 2nd decade CORD macular and peripheral atrophy[]

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