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118 Possible Causes for Frontal Headache, Gliosis

  • Dementia

    Abstract A 42-year-old woman presented with a 6-month history of diffuse headache of moderate intensity and gradual onset of generalized weakness, imbalance, apathy, memory[ncbi.nlm.nih.gov] Small vessel disease results in arterial wall changes, expansion of the Virchow-Robin spaces, and perivascular parenchymal rarefaction and gliosis.[emedicine.medscape.com] With respect to neuronal loss and glial proliferation, Fuller (1911) noticed that the gliosis and the considerable cell loss in AD is equal in extent to the glial proliferation[doi.org]

  • Creutzfeldt Jakob Disease

    In adults, it typically involves the anterior and medial aspects of the temporal lobe and the orbital frontal lobes, often asymmetrically.[doi.org] Extensive spongiform changes were observed in the cerebral neocortex, striatum, thalamus and cerebellar cortex, but gliosis was mild or absent.[ncbi.nlm.nih.gov] This spongiform change begins several months before clinical onset, and is followed by gliosis. Subsequently, neuropil rarefaction appears, followed by neuron loss.[ncbi.nlm.nih.gov]

  • Carbon Monoxide Poisoning

    400 1-2 hours Frontal headache and nausea 800 45 minutes Headache, dizziness and nausea 800 2 hours Collapse and possible unconsciousness 1600 20 minutes Headache, dizziness[carbonmonoxide.ie] A long-term vegetative state causes the brain to soften and liquefy because of reactive gliosis and autolytic change.[ncbi.nlm.nih.gov] The most common location for pain was frontal (66%), although more than one location was involved in 58% of patients.[ncbi.nlm.nih.gov]

  • Subdural Hematoma

    CASE DESCRIPTION: A 55-year-old man was admitted to our hospital complaining of headache, seizure, and urinary incontinence.[ncbi.nlm.nih.gov] The involved hemisphere in survivors shows severe atrophy and neuronal loss and gliosis in the cortex, basal ganglia and thalamus, consistent with unilateral HIE changes.[neuropathology-web.org] Neuroimaging studies revealed a chronic hematic collection in the left frontal-parietal region. Laboratory tests showed increased C-reactive protein levels.[ncbi.nlm.nih.gov]

  • Primary HIV Infection

    CONCLUSIONS: Early in HIV infection, increases of Cho/Cr and MI/Cr in treatment-naive participants suggest progressive inflammation and gliosis in the frontal white matter[ncbi.nlm.nih.gov]

  • Lead Encephalopathy

    […] formation and thickening of the veins with cellular disorganization of their walls (suggesting vascular insult in cerebral injury) is seen. 6 All this can lead to edema, gliosis[ajnr.org]

  • Glaucoma

    Histopathologically, there were data of active inflammatory process, retinal detachment due to huge subretinal osseous metaplasia, gliosis and retinal pigment epithelial hyperplasia[ncbi.nlm.nih.gov] Three and 4 weeks after onset, glaucomatous cupping, necrosis, and marked gliosis with numerous microglia were seen.[doi.org]

  • Mercury Poisoning

    The autopsy revealed a thinned cortex and an atrophy of the cerebellum, a loss of neurons, and gliosis as well as an extremely high mercury content.[frontiersin.org] Organic methylmercury toxicity causes prominent neuronal loss and gliosis in the calcarine and parietal cortices and cerebellar folia, as seen in cases of classic Minamata[emedicine.com] In both cases, brain tissue loss caused by necrosis of neurons and gliosis was mainly found in the cerebral cortex, especially in the calcarine cortex, parietal cortex, and[frontiersin.org]

  • Lead Poisoning

    […] the caudate nuclei and also of the putamen, associated to signal abnormalities that are unspecific, but associated to the atrophy of these structures, can be related to gliosis[doi.org]

  • Kyasanur Forest Disease

    The symptoms of the disease include a high fever with frontal headaches, followed by haemorrhagic symptoms, such as bleeding from the nasal cavity, throat, and gums, as well[en.wikipedia.org] The spectrum of changes included gliosis, inflammatory response, necrosis, neural loss, and syncytium formation in mid and hind brain structures.[ncbi.nlm.nih.gov] Acute onset of malaise, high-grade fever (up to 40 C), chills and typically frontal headaches is experienced after an incubation period of 2-8 days.[symptoma.com]

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