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381 Possible Causes for Frontal Lobe Atrophy

  • Dementia

    Specific degeneration/atrophy of the frontal and temporal lobes of the brain.[] Frontotemporal dementia is associated with pronounced atrophy or shrinkage of the frontal and temporal lobes in the brain.[]

  • Perry Syndrome

    Perry syndrome is a rare atypical parkinsonism with depression, apathy, weight loss, and central hypoventilation caused by mutations in dynactin p150glued (DCTN1). A rare distal hereditary motor neuropathy, HMN7B, also has mutations in DCTN1. Perry syndrome has TAR DNA-binding protein of 43 kDa (TDP-43) inclusions[…][]

  • Frontotemporal Dementia

    At MRI, bilateral frontal lobe atrophy was present. A diagnosis of FTD was made, with a mainly apathetic phenotype.[] E 53, M 1 — 28 CT (1996): marked frontal lobe atrophy. SPECT (1997): marked reduction in perfusion bilaterally to the frontal lobes.[] An MRI scan confirmed marked frontal lobe atrophy, compatible with the diagnosis of FTD.[]

  • Brain Atrophy

    Cotard's syndrome may be associated with multifocal brain atrophy and medial frontal lobe disease.[] , medial temporal lobe atrophy [MTLA] and frontal lobe atrophy [FLA]) with the presence of NPI symptoms and all symptom clusters except euphoria. 11C-Pittsburg Compound B[] The GRN risk SNP (rs5848_T) was associated with a pattern of atrophy in the dorsomedial frontal lobes bilaterally, remarkable since GRN is a risk factor for frontotemporal[]

  • Spinocerebellar Ataxia Type 10

    Although the primary pathology in SCA10 in humans is reportedly the loss of Purkinje cells, brain MRI revealed frontal lobe atrophy with white matter lesions.[]

  • Foster-Kennedy Syndrome

    It is typically due to a frontal lobe tumor (usually an olfactory groove meningioma) which compresses the ipsilateral optic nerve causing its atrophy and also raises the intracranial[] . ipsilateral anosmia contralateral papilloedema due to olfactory bulb meningiomas or plassmacytomas or frontal lobe tumours. 6 Reply Named after neurologist Robert Foster[] Tumor at the base of the frontal lobe produces inappropriate behavior, optic nerve atrophy on the side of the tumor, papilledema on the other side, and anosmia (Foster- Kennedy[]

  • Ring Chromosome 4

    Cranial magnetic resonance imaging (MRI) showed hypoplastic corpus callosum, delayed myelinization, and frontal and occipital lobe atrophies.[]

  • Primary Progressive Aphasia

    At autopsy, the brain showed a marked temporo-frontal lobe atrophy, predominantly on the left side.[] Magnetic resonance imaging of the brain at age 73 demonstrated marked atrophy of the frontal lobes, particularly on the left side.[] MRI scan revealed left temporal lobe atrophy with ex vacuo dilatation of the temporal horn and atrophy of the left inferior frontal gyrus and the left inferior parietal lobe[]

  • Light Chain Disease

    Serum concentrations correlated particularly with frontal lobe atrophy rate (r 0.53, p 0.003).[] Higher concentrations may reflect the intensity of the disease in FTD and are associated with more rapid atrophy of the frontal lobes.[]

  • Pick Disease of The Brain

    This pattern is consistent with the pathologic findings of circumscribed atrophy of the poles of the FRONTAL LOBE and TEMPORAL LOBE.[] […] posterior parietal and frontal corticobasal degeneration atrophy of tectum, globus pallidus, and frontal lobes progressive supranuclear palsy generalised with atrophy of substantia[] Certain important patterns of cerebral atrophy that are more specific include: severe frontal and anterior temporal Pick disease head of caudate nuclei Huntington disease[]

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