Gait Ataxia: Causes & Reasons

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Possible Causes for Gait Ataxia

Niemann-Pick Disease Type C

For the last 5 years, he had developed insidious onset, progressive gait ataxia and dysarthria. [annalsofian.org]

It is characterized clinically by a variety of progressive, disabling neurological symptoms including clumsiness, limb and gait ataxia, dysarthria, dysphagia and cognitive [ncbi.nlm.nih.gov]

Neurological examination at Mayo Clinic revealed oromandibular dystonia, an ataxic and hypokinetic dysarthria, mild hyperreflexia, and gait ataxia. [jnnp.bmj.com]

X-linked Mental Retardation Type Cabezas

ataxia Inability to coordinate movements when walking 0002066 Gynecomastia Enlarged male breast 0000771 Motor delay 0001270 Pes planus Flat feet Flat foot [ more ] 0001763 [rarediseases.info.nih.gov]

[…] speech development Poor language development Speech and language delay Speech and language difficulties Speech delay [ more ] 0000750 Distal lower limb amyotrophy 0008944 Gait [rarediseases.info.nih.gov]

Vitamin B12 Deficiency

He developed aggression, urinary incontinence, gait ataxia, and memory disturbances and was admitted. [doi.org]

It can be a cause of unsteady gait (ataxia), sometimes accompanied by anemia (macrocytic), and loss of position sense. [dizziness-and-balance.com]

Paresthesia - numbness, tingling and pain Confusion / disorientation Weakness of legs, arms, trunk Impaired vibration - position sense Abnormal reflexes Unsteady or abnormal gait [b12deficiency.info]

Hyperornithinemia-Hyperammonemia-Homocitrullinuria Syndrome

At the age of 6 years, the boy had no acute encephalopathy or pyramidal signs, but did exhibit mild clumsiness and subtle gait ataxia (only evident on tandem walking). [hkmj.org]

ataxia, episodic confusion, disorientation, incoherence, agitation, restlessness, headache) [12]. [nature.com]

[…] pharmacological treatment, most of patients reaching adult age present with variable degree of neurological and cognitive impairment and psychiatric symptoms (such as abnormal gait [nature.com]

Stroke

[…] might be present and this includes: altered walking gait altered movement coordination vertigo and or disequilibrium Associated symptoms Loss of consciousness, headache, [en.wikipedia.org]

[…] thinking, confusion, hypersexual gestures (with involvement of frontal lobe) lack of insight of his or her, usually stroke-related, disability If the cerebellum is involved, ataxia [en.wikipedia.org]

Hyperammonemia Type 3

Ataxias Return to Ataxia Syndromes Return to Neuromuscular Home Page References 1. [neuromuscular.wustl.edu]

Intermittent ataxia: unstable gait ,dysmetria. periodic ↑ammonia Intellectual impairment: Episodic hyperammonemia may produce subtle intellectual deficits even in clinically [slideshare.net]

Dysarthria; Gait disorder; Tremor Extrapyramidal: Athetosis; Dystonia Cataplexy Gaze paresis: Especially down; Also up; Supranuclear; In severe forms Hypotonia Neuropathy [neuromuscular.wustl.edu]

Amyotrophic Lateral Sclerosis

Clinical examination, 20 years after the onset of the patient's symptoms, revealed that the boxer had tremor, gait ataxia and pyramidal tract dysfunction, but possessed normal [doi.org]

Homocystinuria

Patients who become symptomatic beyond infancy may present with ataxia, dementia or psychosis. [orpha.net]

Patients with cblD present with severe learning difficulties, behavioral problems and movement and gait abnormalities and patients with cblF and cblJ present with feeding [orpha.net]

Posterior Inferior Cerebellar Artery Occlusion

Embolic source from heart or aorta Dissection Major Signs/Symptoms: Vertigo, nausea, vomiting Ipsilateral limb ataxia (dysmetria, dysdiadochokinesia) Gait ataxia Nystagmus [casemed.case.edu]

A 71-year-old man with a history of hypertension presented with an abrupt gait disturbance. On neurologic examination, he could stand but not walk due to gait ataxia. [n.neurology.org]

[…] pupil & drooping eyelid) • Bradycardia Among these, sensory symptoms & signs, gait ataxia, dizziness and Horner's sign are the most common, with sensory symptoms & signs [physio-pedia.com]

Cerebellar Stroke

After 3 months a mild ataxia in lower limbs and gait, especially in gait speed persisted. [ncbi.nlm.nih.gov]

Midline lesions can produce severe gait and truncal ataxia. [patient.info]

In patients with ataxia of stance, gait and lower limbs lesions were more common in cerebellar lobules IV to VI. [ncbi.nlm.nih.gov]

CANOMAD Syndrome

Signs and symptoms of CANOMAD may include loss of muscle, tendon, and joint sensation, abnormal gait (walk), ataxia, tingling sensation on the skin around the mouth or extremities [malacards.org]

Miller-Fisher Syndrome

On examination, there was ophthalmoplegia, nystagmus, areflexia and lower limb and gait ataxia. [eprints.whiterose.ac.uk]

He developed ophthalmoplegia, diplopia, and gait ataxia for one week. [ncbi.nlm.nih.gov]

During the disease, she subsequently developed bilateral sixth and seventh nerve palsies, gait ataxia, and areflexia. [ncbi.nlm.nih.gov]

Wernicke Encephalopathy

An examination revealed spontaneous upbeat nystagmus ( Video 1 ), gaze-evoked nystagmus ( Video 2 ), and gait ataxia. She had no ophthalmoplegia. [nejm.org]

She also had truncal, stance and gait ataxia. She was treated with parenteral thiamine and her visual loss reversed and her ataxia improved dramatically. [ncbi.nlm.nih.gov]

The classic triad consists of encephalopathy, oculomotor dysfunction and gait ataxia but is not seen in a majority of patients. [ncbi.nlm.nih.gov]

Subacute Combined Degeneration of Spinal Cord

She had positive Lhermitte's and gait ataxia. Rom‐berg's sign was present. [shmabstracts.com]

ataxia distal weakness, especially in legs Subacute Combined Degeneration -syndrome of sensory loss -spastic paresis associated with pathological lesions in dorsal columns [quizlet.com]

Within 3 weeks the gait improved, ataxia, weakness and numbness of the limbs decreased. [neuroanatomy.wisc.edu]

Wernicke-Korsakoff Syndrome

The classical triad of confusion, oculomotor dysfunction, and gait ataxia is seen in about a third of patients. [amboss.com]

Wernicke's encephalopathy is characterized by confusion, abnormal stance and gait ( ataxia ), and abnormal eye movements ( nystagmus ). [rarediseases.info.nih.gov]

Presentation Clinical diagnosis that does not require imaging studies Wernicke's encephalopathy encephalopathy ( disorientation, indifference, inattentiveness) ophthalmoplegia gait [step1.medbullets.com]

Acute Cerebellar Ataxia

The major clinical features were rapid development of gait ataxia, limb ataxia and dysarthria. None of the patients had altered sensorium. [ncbi.nlm.nih.gov]

He developed ophthalmoplegia, diplopia, and gait ataxia for one week. [ncbi.nlm.nih.gov]

The mildest cases of acute cerebellar ataxia represent a benign condition that is characterized by acute truncal and gait ataxia, variably with appendicular ataxia, nystagmus [ncbi.nlm.nih.gov]

Alcoholic Cerebellar Degeneration

Midline lesions can produce severe gait and truncal ataxia. [patient.info]

Clinical manifestations evolve over months to years and include truncal instability, broad-based stance and gait ataxia. [urmc.rochester.edu]

Dysfunction is noted by postural instability and gait ataxia. Cerebellar hemispheres communicate via inferior, middle and superior cerebellar peduncles. [medexam.net]

Spinocerebellar Ataxia Type 13

gait ataxia, upper limb incoordination, and dysarthria. [experts.umn.edu]

gait ataxia associated with cerebellar dysarthria and often accompanied by mild intellectual disability and occasional seizures to adult-onset progressive ataxia. [childnervoussystem.blogspot.com]

In the families described to date, the phenotype of spinocerebellar ataxia type 13 (SCA13) has ranged from slowly progressive childhood-onset cerebellar gait ataxia associated [ncbi.nlm.nih.gov]

Spinocerebellar Ataxia Type 6

Gait ataxia was remarkably reduced again. [ashg.org]

Manual clumsiness, indicative of upper limb ataxia, was always milder than gait ataxia. [doi.org]

A 39-year-old man who showed slowly progressive mental disorders and gait ataxia was clinically diagnosed to have cortical cerebellar atrophy (CCA) and schizophrenia. [ncbi.nlm.nih.gov]

Arnold-Chiari Malformation

Chiari malformations are a group of complex brain abnormalities. Patients with type I CM do not show any symptoms. Adolescents and adults may develop symptoms of CM later in their life. Patients with CM often complain of neck pain or numbness. There are abnormal feelings in the extremities, muscle weakness and[…] [symptoma.com]

Hereditary Areflexic Dystasia

The phenotype differs, however, in that it includes static tremor of the upper limbs and gait ataxia. [uniprot.org]

Decreased motor nerve conduction velocity ; Decreased number of peripheral myelinated nerve fibers ; Distal amyotrophy ; Distal muscle weakness ; Distal sensory impairment ; Gait [mousephenotype.org]

In 1926, Roussy and Lévy described a large family whose members manifested an early onset dominantly inherited gait ataxia, pes cavus, and areflexia, which was eventually [ncbi.nlm.nih.gov]

Machado-Joseph Disease

We describe three patients with the Machado-Joseph disease (MJD) genetic abnormality who had non-movement disorder neurological symptoms or signs that preceded the gait ataxia [ncbi.nlm.nih.gov]

The clinical core features include gait ataxia, external ophthalmoplegia, nystagmus, and bulging eyes. [ncbi.nlm.nih.gov]

Individuals with gait ataxia appear to walk in a “drunk-like” state. [physio-pedia.com]

Autosomal Recessive Spinocerebellar Ataxia 8

Initial symptoms consist of gait ataxia, dysarthria, and dysphagia. [ataxia.uchicago.edu]

ataxia Inability to coordinate movements when walking 0002066 Limb ataxia 0002070 Nystagmus Involuntary, rapid, rhythmic eye movements 0000639 Slow progression Signs and [rarediseases.info.nih.gov]

ataxia 19 See the list below: Clinical features Gait and limb ataxia Cognitive impairment Myoclonus Postural tremor Spinocerebellar ataxia 20 See the list below: Clinical [emedicine.medscape.com]

Spinocerebellar Ataxia Type 23

Symptoms - Spinocerebellar ataxia 23 Gait ataxia Mild sensory neuropathy Speech problems Limb ataxia Eye movement problems Causes - Spinocerebellar ataxia 23 Not supplied. [checkorphan.org]

We experienced a 26-year-old man who presented with a 10-years history of slowly progressive gait ataxia, dysarthria and blepharospasm. [jkna.org]

Affiliated tissues include skeletal muscle, and related phenotypes are muscle weakness and gait ataxia Disease Ontology : 12 An autosomal dominant cerebellar ataxia that is [malacards.org]

Spinocerebellar Ataxia Type 15

The most prevalent symptoms were gait ataxia (88.3%), dysarthria (75.0%), nystagmus (73.3%), and limb ataxia (71.7%). [mayoclinic.pure.elsevier.com]

ataxia, balance impairment, and dysarthria). [ncbi.nlm.nih.gov]

Deletion was found in only one patient, in whom gait ataxia started at 51 years of age and progressed to show cerebellar ataxia. [ncbi.nlm.nih.gov]

Spinocerebellar Ataxia Type 30

Dysarthria, gait ataxia, bradykinesia, hyper-reflexia and dystonia were present in 80%, 80%, 60%, 50 % and 20% patients respectively. [mdsabstracts.org]

SPINOCEREBELLAR ATAXIA 41; SCA41 Is also known as ;sca41 Related symptoms: Autosomal dominant inheritance Ataxia Cerebellar atrophy Progressive Gait ataxia SOURCES: MONDO [mendelian.co]

Adult-Onset Autosomal Recessive Cerebellar Ataxia

Differentiation of imbalance due to frontal gait disorder and extra pyramidal disorders from cerebellar ataxia Features Frontal gait disorder Extrapyramidal Cerebellar ataxia [slideshare.net]

Gait ataxia, dysarthria, dysmetria, nystagmus, muscle wasting and dystonia are seen in the late stages of the disease. [patient.info]

Spinocerebellar Ataxia Type 20

Dysarthria, rather than gait ataxia, was the initial symptom in most, and was typically conjoined with dysphonia, clinically resembling adductor spasmodic dysphonia. [ncbi.nlm.nih.gov]

Dysarthria, gait ataxia, bradykinesia, hyper-reflexia and dystonia were present in 80%, 80%, 60%, 50 % and 20% patients respectively. [mdsabstracts.org]

In the course of disease they develop dysarthria, gait ataxia, bradykinesia and dystonia. Cognition was generally spared but psychiatric symptoms were common. [mdsabstracts.org]

Spinocerebellar Ataxia Type 26

gait ataxia, upper limb incoordination, and dysarthria. [ncbi.nlm.nih.gov]

[…] this term) characterized by late-onset and slowly progressive cerebellar signs (gait ataxia) and eye movement abnormalities. [rarediseases.info.nih.gov]

Dysarthria, gait ataxia, bradykinesia, hyper-reflexia and dystonia were present in 80%, 80%, 60%, 50 % and 20% patients respectively. [mdsabstracts.org]

Spinocerebellar Ataxia Type 5

The latter two findings, along with gait ataxia, are shared features for both SCA2 and 12. [movementdisorders.org]

Video 1 Case 1, Part Ia: Examination at age 28: mild jaw-opening dystonia, limb ataxia, dysarthria, and gait ataxia are shown. [movementdisorders.org]

Moderately severe gait ataxia, moderate degree of intention tremor in upper-limbs, head tremor, dysarthria, and facial myokymia were also noted. [movementdisorders.org]