Gait-ataxia: Causes & Reasons

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Possible Causes for gait ataxia

Vitamin B12 Deficiency

He developed aggression, urinary incontinence, gait ataxia, and memory disturbances and was admitted. [doi.org]

It can be a cause of unsteady gait (ataxia), sometimes accompanied by anemia (macrocytic), and loss of position sense. [dizziness-and-balance.com]

Paresthesia - numbness, tingling and pain Confusion / disorientation Weakness of legs, arms, trunk Impaired vibration - position sense Abnormal reflexes Unsteady or abnormal gait [b12deficiency.info]

Stroke

[…] might be present and this includes: altered walking gait altered movement coordination vertigo and or disequilibrium Associated symptoms Loss of consciousness, headache, [en.wikipedia.org]

[…] thinking, confusion, hypersexual gestures (with involvement of frontal lobe) lack of insight of his or her, usually stroke-related, disability If the cerebellum is involved, ataxia [en.wikipedia.org]

Amyotrophic Lateral Sclerosis

Clinical examination, 20 years after the onset of the patient's symptoms, revealed that the boxer had tremor, gait ataxia and pyramidal tract dysfunction, but possessed normal [doi.org]

Niemann-Pick Disease Type C

It is characterized clinically by a variety of progressive, disabling neurological symptoms including clumsiness, limb and gait ataxia, dysarthria, dysphagia and cognitive [ncbi.nlm.nih.gov]

In addition, impaired vertical saccadic and pursuit eye movements, brisk muscle stretch reflexes and limb and gait ataxia were observed. [annalsofian.org]

Neurological examination at Mayo Clinic revealed oromandibular dystonia, an ataxic and hypokinetic dysarthria, mild hyperreflexia, and gait ataxia. [jnnp.bmj.com]

Cerebellar Stroke

After 3 months a mild ataxia in lower limbs and gait, especially in gait speed persisted. [ncbi.nlm.nih.gov]

Gait instability and gait ataxia are reported in over half of those who experience an infarct in the cerebellum ( 2 ). [frontiersin.org]

Functional recovery and rehabilitation of postural impairment and gait ataxia in patients with acute cerebellar stroke. [frontiersin.org]

Posterior Inferior Cerebellar Artery Occlusion

Embolic source from heart or aorta Dissection Major Signs/Symptoms: Vertigo, nausea, vomiting Ipsilateral limb ataxia (dysmetria, dysdiadochokinesia) Gait ataxia Nystagmus [casemed.case.edu]

A 71-year-old man with a history of hypertension presented with an abrupt gait disturbance. On neurologic examination, he could stand but not walk due to gait ataxia. [n.neurology.org]

Other findings included limb dysmetria (n 55 [67%]), gait ataxia (n 52 [63%]), facial sensory loss (n 23 [28%]), facial weakness (n 23 [21%]), body sensory loss (n 5 [6%]) [ahajournals.org]

CANOMAD Syndrome

Conclusions: CANOMAD syndrome should be considered when patient presents with polyneuropathy with sensory ataxia and ophthalmoparesis. [n.neurology.org]

Signs and symptoms of CANOMAD may include loss of muscle, tendon, and joint sensation, abnormal gait (walk), ataxia, tingling sensation on the skin around the mouth or extremities [malacards.org]

Patient was treated with IVIG with improvement of his vision and gait. He will receive IVIG monthly and a hematology consult is pending. [n.neurology.org]

Wernicke Encephalopathy

She also had truncal, stance and gait ataxia. She was treated with parenteral thiamine and her visual loss reversed and her ataxia improved dramatically. [ncbi.nlm.nih.gov]

The classic triad consists of encephalopathy, oculomotor dysfunction and gait ataxia but is not seen in a majority of patients. [ncbi.nlm.nih.gov]

ataxia. [ncbi.nlm.nih.gov]

Miller-Fisher Syndrome

During the disease, she subsequently developed bilateral sixth and seventh nerve palsies, gait ataxia, and areflexia. [ncbi.nlm.nih.gov]

He developed ophthalmoplegia, diplopia, and gait ataxia for one week. [ncbi.nlm.nih.gov]

The syndrome is characterized by acute onset of gait ataxia, ophthalmoplegia, and areflexia. [ncbi.nlm.nih.gov]

Hyperornithinemia-Hyperammonemia-Homocitrullinuria Syndrome

ataxia, episodic confusion, disorientation, incoherence, agitation, restlessness, headache) [12]. [nature.com]

At the age of 6 years, the boy had no acute encephalopathy or pyramidal signs, but did exhibit mild clumsiness and subtle gait ataxia (only evident on tandem walking). [hkmj.org]

[…] pharmacological treatment, most of patients reaching adult age present with variable degree of neurological and cognitive impairment and psychiatric symptoms (such as abnormal gait [nature.com]

Hyperammonemia Type 3

Ataxias Return to Ataxia Syndromes Return to Neuromuscular Home Page References 1. [neuromuscular.wustl.edu]

Intermittent ataxia: unstable gait ,dysmetria. periodic ammonia Intellectual impairment: Episodic hyperammonemia may produce subtle intellectual deficits even in clinically [slideshare.net]

Dysarthria; Gait disorder; Tremor Extrapyramidal: Athetosis; Dystonia Cataplexy Gaze paresis: Especially down; Also up; Supranuclear; In severe forms Hypotonia Neuropathy [neuromuscular.wustl.edu]

Arnold-Chiari Malformation

Oscillopsia and nystagmus began in a woman 2 weeks after an inadvertent lumbar puncture during anesthesia for childbirth. Examination showed horizontal-torsional jerk nystagmus in all positions of gaze. Magnetic-search-coil oculography revealed accelerating slow phases, with an increase in nystagmus amplitude in[…] [ncbi.nlm.nih.gov]

Acute Cerebellar Ataxia

The major clinical features were rapid development of gait ataxia, limb ataxia and dysarthria. None of the patients had altered sensorium. [ncbi.nlm.nih.gov]

He developed ophthalmoplegia, diplopia, and gait ataxia for one week. [ncbi.nlm.nih.gov]

The mildest cases of acute cerebellar ataxia represent a benign condition that is characterized by acute truncal and gait ataxia, variably with appendicular ataxia, nystagmus [ncbi.nlm.nih.gov]

Spinocerebellar Ataxia Type 13

gait ataxia, upper limb incoordination, and dysarthria. [experts.umn.edu]

In the families described to date, the phenotype of spinocerebellar ataxia type 13 (SCA13) has ranged from slowly progressive childhood-onset cerebellar gait ataxia associated [ncbi.nlm.nih.gov]

[…] characterized by progressive gait ataxia, upper limb incoordination, and dysarthria. [experts.umn.edu]

Hereditary Areflexic Dystasia

The phenotype differs, however, in that it includes static tremor of the upper limbs and gait ataxia. [uniprot.org]

Decreased motor nerve conduction velocity ; Decreased number of peripheral myelinated nerve fibers ; Distal amyotrophy ; Distal muscle weakness ; Distal sensory impairment ; Gait [mousephenotype.org]

ataxia. [diseaseinfosearch.org]

Spinocerebellar Ataxia Type 6

BACKGROUND: Spinocerebellar ataxia type 6 (SCA6) is an inherited ataxia with no established treatment. Gait ataxia is a prominent feature causing substantial disability. [ncbi.nlm.nih.gov]

Gait ataxia was remarkably reduced again. [ashg.org]

Spinocerebellar ataxia 6 (SCA6), an autosomal dominant degenerative disease, is characterized by diplopia, gait ataxia, and incoordination due to severe progressive degeneration [ncbi.nlm.nih.gov]

Spinocerebellar Ataxia Type 15

ataxia, balance impairment, and dysarthria). [ncbi.nlm.nih.gov]

The most prevalent symptoms were gait ataxia (88.3%), dysarthria (75.0%), nystagmus (73.3%), and limb ataxia (71.7%). [mayoclinic.pure.elsevier.com]

Deletion was found in only one patient, in whom gait ataxia started at 51 years of age and progressed to show cerebellar ataxia. [ncbi.nlm.nih.gov]

Cerebellar Ataxia

RESULTS: We described four patients with cerebellar ataxia, predominantly gait ataxia, due to statins use. [ncbi.nlm.nih.gov]

Here, we report two new cases of anti-Ca-associated autoimmune cerebellar ataxia. Patient 1 presented with dizziness and acute yet mild limb and gait ataxia. [ncbi.nlm.nih.gov]

A 40 year-old male presented with the history facial puffiness, hoarseness of voice and gait-ataxia. Investigations revealed frank primary hypothyroidism. [ncbi.nlm.nih.gov]

Alcoholic Cerebellar Degeneration

Midline lesions can produce severe gait and truncal ataxia. [patient.info]

Clinical manifestations evolve over months to years and include truncal instability, broad-based stance and gait ataxia. [urmc.rochester.edu]

Dysfunction is noted by postural instability and gait ataxia. Cerebellar hemispheres communicate via inferior, middle and superior cerebellar peduncles. [medexam.net]

Autosomal Recessive Spinocerebellar Ataxia 8

Initial symptoms consist of gait ataxia, dysarthria, and dysphagia. [ataxia.uchicago.edu]

ataxia Inability to coordinate movements when walking 0002066 Limb ataxia 0002070 Nystagmus Involuntary, rapid, rhythmic eye movements 0000639 Slow progression Signs and [rarediseases.info.nih.gov]

ataxia 19 See the list below: Clinical features Gait and limb ataxia Cognitive impairment Myoclonus Postural tremor Spinocerebellar ataxia 20 See the list below: Clinical [emedicine.medscape.com]

Spinocerebellar Ataxia Type 23

Symptoms - Spinocerebellar ataxia 23 Gait ataxia Mild sensory neuropathy Speech problems Limb ataxia Eye movement problems Causes - Spinocerebellar ataxia 23 Not supplied. [checkorphan.org]

We experienced a 26-year-old man who presented with a 10-years history of slowly progressive gait ataxia, dysarthria and blepharospasm. [jkna.org]

We have identified missense mutations in prodynorphin (PDYN) that cause SCA23 in four Dutch families displaying progressive gait and limb ataxia. [ncbi.nlm.nih.gov]

Spinocerebellar Ataxia Type 20

Dysarthria, rather than gait ataxia, was the initial symptom in most, and was typically conjoined with dysphonia, clinically resembling adductor spasmodic dysphonia. [ncbi.nlm.nih.gov]

The first symptom was dysarthria in nine of 14, gait ataxia in two, and both together in two. [brain.oxfordjournals.org]

The second symptom in those initially manifesting dysarthria was typically gait ataxia (seven out of nine), which followed from 3 months to 25 years later. [brain.oxfordjournals.org]

Hereditary Cerebellar Degeneration

Clinical signs are varied, with some patients having limb and gait ataxia along with episodic headaches or nausea, and others having gait ataxia, speech difficulty, and abnormal [encyclopedia.com]

Gait ataxia is the most typical early symptom of MSA-c. [orpha.net]

Gait ataxia, dysarthria, dysmetria, nystagmus, muscle wasting and dystonia are seen in the late stages of the disease. [patient.info]

Spinocerebellar Ataxia Type 12

OBJECTIVE: SCA12 is a progressive autosomal-dominant disorder, caused by a CAG/CTG repeat expansion in PPP2R2B on chromosome 5q32, and characterized by tremor, gait ataxia [ncbi.nlm.nih.gov]

Dysarthria, gait ataxia, bradykinesia, hyper-reflexia and dystonia were present in 80%, 80%, 60%, 50 % and 20% patients respectively. [mdsabstracts.org]

Gait ataxia developed 1–5 years later after the onset of tremor (median 2 years). [academic.oup.com]

Hereditary ATTR Amyloidosis

History The subtype of transthyretin (TTR) protein mutation, its tissue distribution, and the amount of amyloid deposition largely determine the clinical manifestations of TTR-related amyloidosis (ATTR). The key characteristic of ATTR that should raise clinical suspicion for this disorder remains the reliable[…] [emedicine.medscape.com]

Friedreich Ataxia

Rehabilitation Of Limb And Gait Ataxia In Hereditary Cerebellar Ataxias: A Pilot Open-Labeled Study ,” published in the journal Neurological Sciences. [equistasi.com]

Abstract Friedreich ataxia (FRDA) is an autosomal recessive disease with gait ataxia being the main source of morbidity. [ncbi.nlm.nih.gov]

We describe two sisters with early onset gait ataxia, rapid disease progression, absent or very mild dysarthria and upper limb dysmetria, retained knee jerks in one, slight [ncbi.nlm.nih.gov]

Autosomal Recessive Spinocerebellar Ataxia

The hereditary ataxias are a group of genetic disorders characterized by slowly progressive incoordination of gait and often associated with poor coordination of hands, speech [flybase.org]

Clinical manifestations include gait ataxia, pes cavus, speech impairment, lateral curvature of spine, rhythmic head tremor, kyphoscoliosis, congestive heart failure (secondary [icd9data.com]

Spinocerebellar Ataxia Type 26

gait ataxia, upper limb incoordination, and dysarthria. [ncbi.nlm.nih.gov]

[…] this term) characterized by late-onset and slowly progressive cerebellar signs (gait ataxia) and eye movement abnormalities. [rarediseases.info.nih.gov]

Dysarthria, gait ataxia, bradykinesia, hyper-reflexia and dystonia were present in 80%, 80%, 60%, 50 % and 20% patients respectively. [mdsabstracts.org]

Autosomal Recessive Spinocerebellar Ataxia 18

Buspirone (10 mg TID) produced a mild improvement of gait ataxia. [scielo.br]

Affiliated tissues include skeletal muscle, and related phenotypes are muscle weakness and gait ataxia Disease Ontology : 12 An autosomal dominant cerebellar ataxia that is [malacards.org]

The hereditary ataxias are a group of genetic disorders characterized by slowly progressive incoordination of gait and often associated with poor coordination of hands, speech [flybase.org]

Autosomal Recessive Spinocerebellar Ataxia Type 17

17 is a neurologic disorder characterized by onset of gait ataxia and cerebellar signs in early childhood. [malacards.org]