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482 Possible Causes for Generalized Bilateral Synchronous Symmetrical Discharge, Generalized Spike-and-Slow-Waves, Mild Cerebellar Hypoplasia

  • West Syndrome

    Lennox-Gastaut Syndrome: LGS is characterized by multiple types of seizures and an abnormal EEG with generalized slow spikewave discharges.[cdkl5.com] Magnetic resonance imaging of the brain revealed mild cerebral and cerebellar atrophy, high-signal-intensity areas in the white matter, and hypoplasia of the corpus callosum[ncbi.nlm.nih.gov] Interictal EEG displays diffuse and asynchronous high voltage spikes and slow waves suggesting the hypsarrhythmic pattern. B.[bmcneurol.biomedcentral.com]

  • Epilepsy

    Electroencephalography (EEG) showed progressively slowed background activity and sporadic generalized spike-and-wave discharges.[ncbi.nlm.nih.gov] Neuroimaging studies were unremarkable and electroencephalograms showed high voltage 200-400uV, 2-2.5 Hz generalized spike-and-waves and polyspikes with alternating frontal[ncbi.nlm.nih.gov] […] specified generalized (poly)spike waves, slow spike waves, multifocal discharges, generalized paroxysmal fast activity, diffuse slowing slow background, generalized spike[ncbi.nlm.nih.gov]

    Missing: Mild Cerebellar Hypoplasia
  • Early Infantile Epileptic Encephalopathy Type 6

    Four children had generalized spike and slow wave or polyspike and slow wave.[neurology.org] During disease progression and increased seizure frequency, however, EEG findings eventually reveal both focal and multifocal anomalies, including generalized spike-and-wave[symptoma.com] […] patient with atypical absence epileptic status, characterized by generalized and irregular slow (2Hz) spike-and-wave complexes.[psiquiatriainfantil.com.br]

    Missing: Mild Cerebellar Hypoplasia
  • Benign Adult Familial Myoclonic Epilepsy

    The EEG exhibits periodic complexes with generalized bilateral, usually synchronous and symmetrical sharp and slow wave complexes of high amplitude (greater than 500 uV),[neuroweb.us] , high-amplitude spike and slow-wave complexes 3.5 Hz, typically 4 s duration.  Absence seizures in JAE are more sporadic.  EEG is slightly faster with generalized spike[slideshare.net] hypoplasia-hydranencephaly syndrome Multiple acyl-CoA dehydrogenase deficiency Multiple acyl-CoA dehydrogenase deficiency, mild type Multiple acyl-CoA dehydrogenase deficiency[orpha.net]

  • Angelman Syndrome

    EEG demonstrates high-amplitude 2-3Hz delta activity with spike and slow-wave discharges and sleep-activated generalized epileptiform discharges.[ncbi.nlm.nih.gov] Cerebellar hypoplasia Seizures Pathophysiology [ edit ] Adenylosuccinate lyase deficiency is responsible for a range of symptoms that involve psychomotor retardation, often[en.wikipedia.org] (a) Generalized burst of spike and spike waves with high amplitude, prevalent in the anterior regions, (b) Very slow background activity mixed with multifocal spikes.[ijponline.biomedcentral.com]

  • Idiopathic Generalized Epilepsy

    In idiopathic generalized epilepsy, all seizures are initially generalized with an EEG expression that is a generalized, bilateral, synchronous, symmetrical discharge.[humpath.com] […] epilepsy K complex lambda mu OIRDA PLEDs phantom spike and wave photic driving photoparoxysmal response photomyogenic artifact poly spike and wave posterior dominant rhythm[eegatlas-online.com] Seizures are initially generalized with a bilateral, synchronous, generalized, symmetrical EEG discharge ({19:Zara et al., 1995}; {8:Lu and Wang, 2009}).[diseaseinfosearch.org]

    Missing: Mild Cerebellar Hypoplasia
  • Generalized Clonic or Tonic-Clonic Seizures

    discharge are bilateral and fairly symmetric ( 3 ).[pubs.rsna.org] , poly spike discharges." [2] The clonic phase EEG will show "high amplitude activity that is typically interrrupted by slow waves to create a spike-and-slow-wave pattern.[en.wikipedia.org] Abnormal bihemispheric synchronization in patients with GTCS during generalized spike-wave discharges is implicated as a cause of enhanced interhemispheric communication or[pubs.rsna.org]

    Missing: Mild Cerebellar Hypoplasia
  • Lennox-Gastaut Syndrome

    The epileptic discharges were characterized by bilateral symmetrical synchronous generalized discharge or bilateral asymmetrical discharge or bilateral asynchronous discharge[ncbi.nlm.nih.gov] The semiology of seizures progressively changed to generalized episodes of hypertonia and myoclonus, with slow spike-wave electroencephalographic activity.[ncbi.nlm.nih.gov] Lennox-Gastaut syndrome (LGS) is a childhood epileptic encephalopathy characterized by an electroclinical triad of generalized slow spike wave (SSW) activity in the EEG, multiple[ncbi.nlm.nih.gov]

    Missing: Mild Cerebellar Hypoplasia
  • Juvenile Myoclonic Epilepsy

    […] multiple spike and spike slow wave discharges (in an untreated patient).8 The possible factors responsible for the delay in the diagnosis of JME were studied retrospectively[neurologyindia.com] slow wave discharges.[en.wikipedia.org] […] high frequency (10-16 Hz) spikes, usually followed by slow waves in a frequency of 2,5-5Hz [ 8 ].[omicsonline.org]

    Missing: Generalized Bilateral Synchronous Symmetrical Discharge Mild Cerebellar Hypoplasia
  • Absence Seizure

    Contrary to secondary bilateral synchrony, primary bilateral synchrony manifests with more rapid symmetrical and synchronous generalized spike-wave discharges caused by a[medlink.com] spike-and-slow wave dischargesAbsence seizures are broadly divided into typical and atypical types: Typical absence seizures usually occur in the context of idiopathic generalised[en.wikipedia.org] Classic absence seizures display generalized spikes and slow-wave complexes at 3 Hz during the ictal phase. 1,3,6 Usually, patients are asked to overbreathe for up to 3 minutes[uspharmacist.com]

    Missing: Mild Cerebellar Hypoplasia

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