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18 Possible Causes for Generalized Dystonia, Leukocytosis, Lower Motor Neuron Signs - Later

  • Paraneoplastic Syndrome

    Movement disorders include oro-lingual-facial dyskinesias, generalized chorea, oculogyric crisis, dystonia, and rigidity.[clinlabnavigator.com] […] sclerosis Definition / general: Rarely caused by breast cancer 50% develop lower motor neuron signs eventually Retinal degeneration Definition / general: Destruction of photoreceptors[pathologyoutlines.com] Published September 1989 Abstract Previously we reported that a clonal squamous cell carcinoma cell line (T3M-1) derived from a lower jaw cancer of a patient with marked leukocytosis[cancerres.aacrjournals.org]

  • Extrapyramidal Disorder

    In a majority of individuals, dystonia becomes generalized and disabling ( Figure 1B, 1F, 1H ). Progressive dystonia of the trunk may lead to severe dystonic scoliosis.[ncbi.nlm.nih.gov] Clinical phenomena usually consist of a mixture of lower and upper motor neuron signs, dementia, and urinary dysfunction.[jnnp.bmj.com] […] tachycardia, labile blood pressure, tachypnea, diaphoresis, dysrhythmias) Mental status change: confusion, delirium, reduced vigilance, stupor Diagnostics Creatinine kinase Leukocytosis[amboss.com]

  • Constitutional Anemia due to Iron Metabolism Disorder

    [primary TOR1A (DYT1)] G31.82 Leigh's disease G40.301 - G40.319 Generalized idiopathic epilepsy and epileptic syndromes [nonspecific myoclonic epileptic seizures (MERRF)[aetna.com] […] anemia bone marrow, HEP, Iron, fecal occult blood, urinalysis, smear for parasites indications for bone marrow exams in anemia other unexplained cytopenias, unexplained leukocytosis[quizlet.com] Familial Amyotrophic Lateral Sclerosis (SOD1 Mutation) Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease involving both the upper motor neurons[aetna.com]

  • Ischemic Peripheral Neuropathy

    Leukocytosis may be present, but is often absent in diabetic patients.[clevelandclinicmeded.com] Lateral sclerosis is the loss of axons in the lateral columns of the spinal cord (the upper motor neurons of the corticospinal tracts).[britannica.com] Generalized dystonia (e.g., dystonia musculorum deformans) is an inherited condition in which persistent and often painful twisting and writhing movements of any muscle group[britannica.com]

  • Spinal Demyelination

    Generalized dystonia (e.g., dystonia musculorum deformans) is an inherited condition in which persistent and often painful twisting and writhing movements of any muscle group[britannica.com] Complete blood count with differential to assess for leukocytosis and presence of infection or active autoimmune process. C-reactive protein (CRP).[clinicaladvisor.com] Lateral sclerosis is the loss of axons in the lateral columns of the spinal cord (the upper motor neurons of the corticospinal tracts).[britannica.com]

  • Oculomotor Apraxia

    . : Severe generalized dystonia as a presentation of a patient with aprataxin gene mutation . Mov Disord 2003, 18 :1198–1200. PubMed CrossRef Google Scholar 35.[link.springer.com] Patient II-4 of family 3 presents, in addition to the clinical picture of AOA2, an unusual severe lower motor neuron impairment.[jamanetwork.com] Laboratory studies showed leukocytosis in the upper limits of normal, mildly elevated erythrocyte sedimentation rate, and non-reactive syphilis serologies.[webeye.ophth.uiowa.edu]

  • Meningeal Disorder

    Generalized dystonia (e.g., dystonia musculorum deformans) is an inherited condition in which persistent and often painful twisting and writhing movements of any muscle group[britannica.com] Leukocytosis CBI#10-13 POLYMORPHONUCLEAR LEUKOCYTOSIS (neutrophilia) may be subsequent to acute inflammations.[jan.ucc.nau.edu] […] is bent forwards, backwards, or to the side that are present in normal infants and are incorporated in many bodily movements of normal children and adults tonic seizure generalized[strokecenter.org]

  • Autosomal Dominant Myoglobinuria

    Cognitive impairment Ataxia Generalized hypotonia Intellectual disability Distal upper limb amyotrophy Mild proteinuria Distal lower limb amyotrophy Axonal loss Onion bulb[mendelian.co] Motor neuron loss in cerebral cortex, spinal cord and lower brainstem: amyotrophic lateral sclerosis (ALS).[therapyedu.com] Pyuria-rationale: pyelonephritis is diagnosed by the presence of pyuria, leukocytosis,hematuria, and bacteriuria. the client exhibits fever, chills, and flank pain. myoglobinuria[proprofs.com]

  • Hereditary Thrombophilia due to Congenital Protein S Deficiency

    [primary TOR1A (DYT1)] G31.82 Leigh's disease G40.301 - G40.319 Generalized idiopathic epilepsy and epileptic syndromes [nonspecific myoclonic epileptic seizures (MERRF)[aetna.com] The leukocyte count is variable, but often there may be a mild or moderate leukocytosis.[glowm.com] Familial Amyotrophic Lateral Sclerosis (SOD1 Mutation) Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease involving both the upper motor neurons[aetna.com]

  • Alopecia - Hypogonadism - Extrapyramidal Syndrome

    The index patient was a 25-year-old woman who presented with generalized dystonia involving the trunk and all four limbs.[cags.org.ae] […] neuronopathy with early upper-motor neuron findings followed later by signs of lower-motor neuron dysfunction, and a slowly progressive disease course.[nbiacure.org] Episodic fever Lipodystrophy Polycythemia Scleroderma Lipoatrophy Microcytic anemia Elevated erythrocyte sedimentation rate Increased antibody level in blood Hallux valgus Leukocytosis[mendelian.co]

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