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1,425 Possible Causes for Generalized Dystonia, Lower Motor Neuron Signs - Later, Thromboangiitis Obliterans

  • Ischemic Peripheral Neuropathy

    Generalized dystonia (e.g., dystonia musculorum deformans) is an inherited condition in which persistent and often painful twisting and writhing movements of any muscle group[britannica.com] Thromboangiitis obliterans (Buerger's disease) is an inflammatory segmental thrombotic disease of the medium and small vessels of the extremities usually associated with smoking[clevelandclinicmeded.com] Lateral sclerosis is the loss of axons in the lateral columns of the spinal cord (the upper motor neurons of the corticospinal tracts).[britannica.com]

  • Mitochondrial Membrane Protein-Associated Neurodegeneration

    Conclusions MPAN is characterized by a juvenile‐onset, slowly progressive phenotype with predominant lower limb spasticity, generalized dystonia, and cognitive impairment.[ingentaconnect.com] Early upper motor neuron signs (pyramidal signs, e.g. spasticity) are constant findings and are later followed by signs of lower motor neuron dysfunction (deep tendon reflex[malacards.org] Conclusions MPAN is characterized by a juvenile-onset, slowly progressive phenotype with predominant lower limb spasticity, generalized dystonia, and cognitive impairment.[push-zb.helmholtz-muenchen.de]

    Missing: Thromboangiitis Obliterans
  • Reflex Sympathetic Dystrophy

    In this study, 10 severely affected RSD patients who progressed to multifocal or generalized tonic dystonia underwent H-reflex evaluation, needle electromyography (EMG), polysomnography[ncbi.nlm.nih.gov] Additionally, patients with dystonia lack the ability to generate negative reflex gains for position feedback, for these same disturbances.[ncbi.nlm.nih.gov]

    Missing: Lower Motor Neuron Signs - Later
  • Amyotrophic Lateral Sclerosis Type 5

    ALS2 mutations: Juvenile amyotrophic lateral sclerosis and generalized dystonia.[discovery.ucl.ac.uk] AB - Juvenile amyotrophic lateral sclerosis (ALS) is a form of chronic motor neuron disease characterized by combined upper and lower motor neuron symptoms and signs with[jhu.pure.elsevier.com] CONCLUSIONS: We report generalized dystonia and cerebellar signs in association with ALS2-related disease.[foundationdystoniaresearch.org]

    Missing: Thromboangiitis Obliterans
  • Oculomotor Apraxia

    . : Severe generalized dystonia as a presentation of a patient with aprataxin gene mutation . Mov Disord 2003, 18 :1198–1200. PubMed CrossRef Google Scholar 35.[link.springer.com] Patient II-4 of family 3 presents, in addition to the clinical picture of AOA2, an unusual severe lower motor neuron impairment.[jamanetwork.com] obliterans (Buerger).[pubs.sciepub.com]

  • Peripheral Neuropathy

    Overview Peripheral neuropathy, a result of damage to the nerves outside of the brain and spinal cord (peripheral nerves), often causes weakness, numbness and pain, usually in your hands and feet. It can also affect other areas of your body. Your peripheral nervous system sends information from your brain and[…][mayoclinic.org]

    Missing: Generalized Dystonia Lower Motor Neuron Signs - Later
  • Gout

    Spinal gout is rarely encountered in clinical practice, is easily misdiagnosed, and often remains undiagnosed. This paper aims to provide some clues that are the salient diagnostic features of spinal gout, particularly axial pain, radiculopathy, and myelopathy, as determined on the basis of our experience with a few[…][ncbi.nlm.nih.gov]

    Missing: Generalized Dystonia Lower Motor Neuron Signs - Later
  • Raynaud Phenomenon

    ., drug-induced RS), that associated with thromboangiitis obliterans and with occupational vibration exposure.[academic.oup.com] Raynaud's phenomenon may be caused by any form of narrowing arterial disease, such as ATHEROSCLEROSIS , Buerger's disease ( THROMBOANGIITIS OBLITERANS ), EMBOLISM , THROMBOSIS[medical-dictionary.thefreedictionary.com] obliterans (Buerger's disease) - very rare Neurological disorders Carpal Tunnel syndrome and the Thoracic Outlet syndrome (eg from a cervical rib) Drugs / other chemicals[pcds.org.uk]

    Missing: Generalized Dystonia Lower Motor Neuron Signs - Later
  • Neurodegeneration with Brain Iron Accumulation

    […] as great as the benefit reported in patients with primary generalized dystonias or some other secondary dystonias.[ncbi.nlm.nih.gov] Here, we report three C19orf12-mutant patients from two families presenting with predominant upper and lower motor neuron dysfunction mimicking amyotrophic lateral sclerosis[ncbi.nlm.nih.gov] CONCLUSIONS: MPAN is characterized by a juvenile-onset, slowly progressive phenotype with predominant lower limb spasticity, generalized dystonia, and cognitive impairment[ncbi.nlm.nih.gov]

    Missing: Thromboangiitis Obliterans
  • Juvenile Primary Lateral Sclerosis

    CONCLUSIONS: We report generalized dystonia and cerebellar signs in association with ALS2-related disease.[foundationdystoniaresearch.org] El Escorial criteria for the diagnosis of amyotrophic lateral sclerosis 7 : it requires the presence of signs of lower motor neuron (LMN) degeneration by clinical, electrophysiological[radiopaedia.org] Lower motor neuron loss causes initially increased electrical excitability leading to fasciculations, and later muscle weakness and atrophy; upper motor neuron involvement[neuropathology-web.org]

    Missing: Thromboangiitis Obliterans

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