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39 Possible Causes for Generalized Loss of Subcutaneous Fat

  • Congenital Generalized Lipodystrophy Type 4

    Congenital generalized lipodystrophy type 4 is an extremely rare autosomal recessive disorder. We report our clinical experience on two unrelated Turkish patients with congenital generalized lipodystrophy type 4. A 13-year-old girl (patient-1) presented with generalized lipodystrophy and myopathy. Further tests[…][ncbi.nlm.nih.gov]

  • Insulin Resistance

    Physical examination revealed generalized loss of subcutaneous fat, confirmed by DEXA (total body fat 8.6%).[ncbi.nlm.nih.gov] As the patient presented with pubertal-onset of generalized lipodystrophy and insulin resistance, molecular analysis of the LMNA gene was performed.[ncbi.nlm.nih.gov]

  • Acquired Generalized Lipodystrophy

    She had coarse facial features with generalized loss of subcutaneous fat and prominent muscularity.[ncbi.nlm.nih.gov] At clinical examination a generalized loss of subcutaneous fat that included the face and the extremities was observed. Laboratory tests showed a poor glicemic control.[endocrine-abstracts.org] A six-year- old girl followed with the diagnosis of autoimmune hepatitis showed a severe loss of fat tissue, hyperinsulinemia, impaired glucose tolerance, hypertriglyceridemia[scienceopen.com]

  • Lipedema

    We are not concerned in this presentation with the type of lipodystrophy (lipodystrophia progressiva) which is generally felt to be characterized by loss of subcutaneous fat[annals.org]

  • Generalized Lipodystrophy

    We report two siblings of Hispanic origin who displayed characteristic features of CGL such as generalized loss of subcutaneous fat from birth, acanthosis nigricans, acromegaloid[ncbi.nlm.nih.gov] At clinical examination a generalized loss of subcutaneous fat that included the face and the extremities was observed. Laboratory tests showed a poor glicemic control.[endocrine-abstracts.org] On examination, she had generalized loss of subcutaneous fat, with prominent subcutaneous veins; there was severe acanthosis nigricans involving all flexures, generalized[ijdvl.com]

  • Steatorrhea

    General: Orthostatic hypotension, weight loss, muscle wasting, loss of subcutaneous fat, pallor, ecchymosis.[hawaii.edu]

  • Mandibular Hypoplasia - Deafness - Progeroid Syndrome

    Reinier, F., Zoledziewska, M., Hanna, D. , Smith, J. D. , Valentini, M., Zara, I., ... Crisponi, L. (2015). Mandibular hypoplasia, deafness, progeroid features and lipodystrophy (MDPL) syndrome in the context of inherited lipodystrophies . Metabolism , 64 (11), 1530-1540. DOI: 10.1016/j.metabol.2015.07.022 Mandibular hypoplasia,[…][iths.pure.elsevier.com]

  • Marasmus

    Protein wasting in kwashiorkor generally leads to edema and ascites, while muscular wasting and loss of subcutaneous fat are the main clinical signs of marasmus.The prognosis[en.wikipedia.org] Protein wasting in kwashiorkor generally leads to edema and ascites , while muscular wasting and loss of subcutaneous fat are the main clinical signs of marasmus. [ citation[en.wikipedia.org]

  • Stiff Skin Syndrome

    Loss of subcutaneous fat e.g. generalized lipodystrophy.[drmhijazy.com] ACROGERIA Acrogeria is characterized by cutaneous atrophy and loss of subcutaneous fat particularly over the distal extremities, leading to premature aging of the extremities[drmhijazy.com] Death usually occurs in the second decade as a result of severe generalized atheroma.[drmhijazy.com]

  • Peroneal Nerve Compression Neuropathy

    The report's authors, Teoman Toni Sevinç and colleagues, concluded that in cases where nerve entrapment presents, changes in subcutaneous fat from weight loss might be one[livestrong.com] Symptoms General symptoms of nerve compression include pain, numbness, tingling and muscle weakness to the affected area.[livestrong.com]

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