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516 Possible Causes for Generalized Lymphadenopathy, Hepatosplenomegaly

  • Infectious Mononucleosis

    lymphadenopathy, including cervical lymphadenopathy tonsillar enlargement possible hepatomegaly Treatment and prognosis Symptomatic therapy is usually sufficient.[radiopaedia.org] Both cases involved young adults presenting with fever, pharyngitis, lymphadenopathy, hepatosplenomegaly, and atypical lymphocytosis confirmed by serologic tests, liver biopsy[ncbi.nlm.nih.gov] There is an increase in mononuclear white blood cells and other atypical lymphocytes, generalized lymphadenopathy, splenomegaly, and occasionally hepatomegaly with hepatitis[fpnotebook.com]

  • Angioimmunoblastic Lymphadenopathy

    A 55-year-old Japanese man presented with red papular lesions on the trunk and limbs, oedema, and generalized lymphadenopathy.[ncbi.nlm.nih.gov] AILD is characterized by generalized lymphadenopathy, hepatosplenomegaly, immunological abnormalities, polyclonal hypergammaglobulinemia and anemia.[ncbi.nlm.nih.gov] Although complete remission of AML was achieved, fever persisted and atypical skin rash followed by generalized lymphadenopathy along with polyclonal hypergammaglobulinemia[ncbi.nlm.nih.gov]

  • Leukemia

    Dogs are usually seen with generalized, rapidly progressive lymphadenopathy.[ncbi.nlm.nih.gov] […] lymphocytic leukemia is a rare form of leukemia, caused by clonal proliferation of cytotoxic T-cells, characterized by modest lymphocytosis and cytopenias of other lineage with hepatosplenomegaly[ncbi.nlm.nih.gov] An additional eight features were present in a third to a half of children: recurrent infections (49%), fatigue (46%), limb pain (43%), hepatosplenomegaly (42%), bruising[ncbi.nlm.nih.gov]

  • Syphilis

    lymphadenopathy (14%), and ascites (9%).[doi.org] Among 139 infants with symptomatic congenital syphilis in 3 series, the most common early signs were hepatosplenomegaly (71%), rash (68%), fever (42%), neurosyphylis (23%)[doi.org] […] syphilis in 3 series, the most common early signs were hepatosplenomegaly (71%), rash (68%), fever (42%), neurosyphylis (23%), pneumonitis (17%), rhinitis ( snuffles ; 14%), generalized[doi.org]

  • Gaucher Disease

    Protein-losing enteropathy due to massive mesenteric lymphadenopathy is a rare complication of Gaucher disease which is generally refractory to treatment with enzyme replacement[ncbi.nlm.nih.gov] We report here the case of a young woman with hepatosplenomegaly, leukopenia, and thrombocytopenia.[ncbi.nlm.nih.gov] Abstract The hematologist is at the forefront of specialists to whom patients with Gaucher disease present because of cytopenia and hepatosplenomegaly.[ncbi.nlm.nih.gov]

  • Chronic Lymphocytic Leukemia

    In the physical examination, generalized lymphadenopathy and hepato- and/or splenomegaly may be noted.[symptoma.com] III Lymphocytosis; lymphadenopathy; hepatosplenomegaly, anemia IV Lymphocytosis, lymphadenopathy; hepatosplenomegaly, thrombocytopenia anemia CHRONIC LYMPHOCYTIC LEUKEMIA[medical-dictionary.thefreedictionary.com] Clinical Information A chronic leukemia characterized by abnormal b-lymphocytes and often generalized lymphadenopathy.[icd9data.com]

  • Multiple Myeloma

    Abstract A 75-year-old male presented with generalized erythematous, scaly plaques and painless lymphadenopathy.[ncbi.nlm.nih.gov] The presenting problem was proteinuria in five patients, thyromegaly in three patients, and hepatosplenomegaly in one patient.[jamanetwork.com] […] they reported a progression-free survival of 2, 10 and 46% for the presence of none, one or two risk factors, respectively at 5 years in MGUS. 17 The age, sex, presence of hepatosplenomegaly[doi.org]

  • Multicentric Castleman's Disease

    Multicentric Castleman's disease (MCD) is a rare disorder characterized by fever, polyclonal hypergammaglobulinemia, and generalized lymphadenopathy.[ncbi.nlm.nih.gov] A 46-year-old man presented with a high-grade fever, multiple lymphadenopathies, hepatosplenomegaly and human immunodeficiency virus (HIV) seropositivity, without severe immunosuppression[ncbi.nlm.nih.gov] Multicentric Castleman's Disease (MCD) is a systemic disease characterized by generalized lymphadenopathy and the proliferation of plasma cells.[ncbi.nlm.nih.gov]

  • Adult-Onset Still Disease

    […] more common in young adults Sites Systemic disease Generalized lymphadenopathy Pathophysiology Pathophysiology is yet to be clearly defined Interleukins, macrophage colony[pathologyoutlines.com] Other common manifestations of AOSD are lymphadenopathy, hepatosplenomegaly, muscle aches, and pharyngitis.[symptoma.com] It differs from classical rheumatoid arthritis in that it is more often marked by acute febrile onset, and generalized lymphadenopathy and hepatosplenomegaly are more prominent[icd10data.com]

  • Juvenile Onset Stills Disease

    Appearance of rash, hepatosplenomegaly, serositis and generalized lymphadenopathy.[symptoma.com] lymphadenopathy, hepatomegaly and/or splenomegaly, or serositis (pleuritis or pericarditis).[stillsdisease.org] It differs from classical rheumatoid arthritis in that it is more often marked by acute febrile onset, and generalized lymphadenopathy and hepatosplenomegaly are more prominent[icd10data.com]

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