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315 Possible Causes for Generalized Lymphadenopathy, Langerhans Cell Histiocytosis

  • Langerhans-Cell Histiocytosis

    A 2-year-old boy presented with generalized lymphadenopathy, fever, and cough. The patient had hepatosplenomegaly, anemia, and lytic lesions in the skull.[ncbi.nlm.nih.gov] Langerhans cell histiocytosis (LCH), also called Histiocytosis X, is a rare disease characterized by the proliferation and accumulation of Langerhans cells in various tissues[symptoma.com] Additional signs are fatigue, generalized weakness, weight loss, night sweats, nausea, and fever.[doi.org]

  • Eosinophilic Granuloma

    A case of unifocal Langerhans' cell histiocytosis or eosinophilic granuloma in a child is reported where the frontal, zygomatic and maxillary bones of the left orbital wall[ncbi.nlm.nih.gov] Eosinophilic granuloma is the localized and most benign form of Langerhans' cell histiocytosis.[ncbi.nlm.nih.gov] Langerhans cell histiocytosis (LCH)) changed several names until it was renamed in 1985 by the Histiocyte Society: Hand–Schüller–Christian disease, Abt-Letterer-Siwe disease[minclinic.ru]

  • Rosai-Dorfman Disease

    A provisional diagnosis of fever with generalized lymphadenopathy was made and the patient was admitted for further evaluation.[ncbi.nlm.nih.gov] Langerhans cell histiocytosis (LCH) is a clonal histiocytosis with a wide spectrum of presentations ranging from isolated skin or bone disease to multisystem involvement.[ncbi.nlm.nih.gov] Rosai-Dorfman disease is a rare non-Langerhans cell histiocytosis, mainly involving cervical nodes.[ncbi.nlm.nih.gov]

  • Malignant Histiocytosis

    All had localized or generalized lymphadenopathy and three had hepatosplenomegaly at initial presentation.[ncbi.nlm.nih.gov] Involvement of the thyroid gland by Langerhans' cell histiocytosis is quite rare.[ncbi.nlm.nih.gov] lymphadenopathy and pancytopenia.[ncbi.nlm.nih.gov]

  • Dermatopathic Lymphadenopathy

    […] lymphoma characterized by fever, night sweats, weight loss, generalized lymphadenopathy, hepatosplenomegaly, macropapular rash, polyclonal hypergammaglobulinemia, and Coombs[medical-dictionary.thefreedictionary.com] Lymph node involvement by Langerhans cell histiocytosis: a clinicopathologic and immunohistochemical study of 20 cases. Hum Pathol. 2007;38:1463–9.[link.springer.com] Dermatopathic lymphadenopathy, abbreviated DL, is a rare pathology of the lymph nodes. General Lymphadenopathy associated with a skin lesion.[librepathology.org]

  • Hydroa Vacciniforme-Like Lymphoma

    lymphadenopathy.[ncbi.nlm.nih.gov] […] types) Classical Hodgkin lymphoma PTLD Histiocytic and dendritic cell neoplasms Histiocytic sarcoma Langerhans cell histiocytosis Langerhans cell sarcoma Indeterminate dendritic[nhlcyberfamily.org] cell histiocytosis Langerhans cell sarcoma indeterminate dendritic cell tumor interdigitating dendritic cell sarcoma follicular dendritic cell sarcoma inflammatory pseudotumor-like[radiopaedia.org]

  • Hepatosplenic Amyloidosis

    […] related to acute monocytic leukemia) Dendritic-cell related Langerhans cell histiocytosis Localized, generalized Indolent, progressive Langerhans cell sarcoma Interdigitating[dartmouth.edu] Histiocytic Sarcoma and Langerhans Cell Histiocytosis Narendranath Epperla and Ehab Atallah 49.[springerpub.com] cell histiocytosis (histiocytosis X) Lymphangioleiomyomatosis Lymphocytic interstitial pneumonitis (LIP) Nonspecific interstitial pneumonia (NSIP) Pneumoconioses Respiratory[surgpathcriteria.stanford.edu]

  • Acute Monocytic Leukemia

    The patient studied initially had a low-grade, B-cell, non-Hodgkin lymphoma and subsequently had an unusual histiocytic proliferation (precursor Langerhans cell histiocytosis[ncbi.nlm.nih.gov] cell histiocytosis.[ncbi.nlm.nih.gov] A larger series is required to determine the significance of the precursor Langerhans cell phenotype, particularly with respect to the development of acute myelogenous leukemia[ncbi.nlm.nih.gov]

  • Chronic Myelomonocytic Leukemia

    CMML is generally diagnosed in the elderly, but the clinical presentation of affected individuals varies largely.[symptoma.com] Langerhans cell histiocytosis (LCH) is a rare histiocytic neoplasm characterized by clonal proliferation of Langerhans cells in multi-organ systems including skin, bone, pituitary[ncbi.nlm.nih.gov] Arceci discusses the pathogenesis of Langerhans cell histiocytosis (LCH) in terms of the hypothesis that this disorder represents an atypical myeloproliferative syndrome.[doi.org]

  • Lymphoma

    When more than one area of lymph nodes is swollen it’s called generalized lymphadenopathy.[m.cancer.org] Cytologically benign proliferations of Langerhans cells are called LANGERHANS CELL HISTIOCYTOSIS. Year introduced: 2008 Select item 68054747 7.[ncbi.nlm.nih.gov] The evolution is generally favorable with spontaneous healing after a few weeks.[ncbi.nlm.nih.gov]

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