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14 Possible Causes for Generalized Motor Seizure, Hyperintensities in the Globus Pallidus (T2-Weighted)

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  • Binswanger Disease

    The bilateral cerebral white matter and globus pallidus appeared hyperintense on T2-weighted imaging (Figures 5 and 6). 5) Figure 5. CO poisoning(FLAIR image) Figure 6.[] The hippocampus, cerebral white matter, basal ganglion, and other areas appear hyperintense on T2-weighted imaging. CO poisoning: Delayed diffuse demyelination.[] No contrast enhancement effect is evident. (4) Poisoning and metabolic disorders Hypoxic encephalopathy: Diffusion-weighted imaging is useful for diagnosis.[]

  • Alpers Syndrome

    Children present with seizures in half of the cases. Seizures may be focal, generalized or myoclonic.[] The right parietal cortex appears normal in the T2-weighted images.[] motor status epilepticus. 20, 46, 47 EPC is a motor seizure that involves only one part of the body, such as the hand, face, or arm, with a constant and repetitive clonic[]

  • Creutzfeldt Jakob Disease

    Creutzfeldt Jakob disease is characterized by dementia, motor dysfunction, twitches, seizures, psychosis, and hallucinations.The duration of the disease is generally less[] Extrapontine myelinolysis manifests predominantly as areas of bilateral FLAIR /T2-weighted imaging hyperintensity in the globus pallidus, putamen, and thalamus, which are[] MR imaging abnormalities consist primarily of restricted hyperintensity in the striatum on diffusion-weighted and FLAIR /T2-weighted images ( Fig 20 ), with a peculiar anteroposterior[]

  • Fucosidosis

    Figure 2: Magnetic resonance imaging brain T2-weighted axial image showing hypointensity of globus pallidus bilaterally and the subcortical hyperintensity (a), T1-weighted[] globus pallidus hypointensity signaling on T2-weighted imaging.[] To the best of our knowledge, the combination of hypointensity of the globus pallidus and hyperintensity in its laminae on T2-weighted MR images has not been reported in other[]

  • Wilson Disease

    On T1W images, these lesions are normal to hypointense but hyperintense lesions especially in globus pallidus may also be seen [ 2 ].[] The lesions showed no signal-intensity abnormality on T2-weighted images. The cause of hyperintensity in T1-weighted images remains elusive.[] Figure 1: MRI brain T2-weighted image shows abnormal hyperintensity in pons with characteristic hypointense ‘trident’ sign ( A ) and characteristic ‘face of giant panda’ sign[]

  • Bilirubin Encephalopathy

    In the appropriate clinical context, bilateral globus pallidus T2-weighted and FLAIR signal hyperintensity is supportive of a diagnosis of kernicterus in an infant.[] A limited investigation of diffusion-weighted imaging (DWI) showed no distinctive signal pattern, but a larger study is required.[]

  • Cyanide Exposure

    […] recovery images in the region of the striatum and the globus pallidus.[] Six weeks after the acute cyanide poisoning, areas of hemorrhagic necrosis with hyperintense signal changes could be seen on the T2-weighted and fluid-attenuated inversion[] The unenhanced T1-weighted studies also showed hyperintense signal in the basal ganglia and linear changes along the sensorimotor cortex, consistent with hemorrhage.[]

  • Neurodegeneration with Brain Iron Accumulation

    Seizure types including generalized (absence, tonic, atonic, tonic-clonic and myoclonic), focal with impaired consciousness, and epileptic spasms, as well as epileptic syndromes[] Even before the globus pallidus hypointensity developed, patients with mutations could be distinguished by the presence of isolated globus pallidus hyperintensity on T2-weighted[] ) in specific brain regions (including globus pallidus interna and externa, substantia nigra, thalamus, putamen, and caudate) on T1- and T2-weighted studies, presence of the[]

  • Alexander Disease

    Clinical presentation of the neonatal form is distinguished by leukodystrophy and generalized, frequent, and intractable seizures.[] In addition, there are symmetrical hyperintensity signals in the posterior part of the globus pallidus on T2-weighted images in the two symptomatic patients, which are rarely[] Those with a neonatal onset (within the first 30 days) usually have a more severe disease course presenting with symptoms of generalized, frequent, and often intractable seizures[]

  • Disulfiram

    […] in the globus pallidus.[] Magnetic resonance imaging with gadolinium enhancement showed brain lesions consistent with Wernicke encephalopathy, but also symmetric hyperintensities on T2-weighted images[]

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