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997 Possible Causes for Generalized Motor Seizure, Most Patients Have Adult Onset of Symptoms, Mutation in the CALM2 Gene

  • Ventricular Arrhythmia

    LQT15LQT15 is caused by heterozygous mutations in the CALM2 (Calmodulin 2) gene (114182) on chromosome 2p21.[en.wikipedia.org] LQT14LQT14 is caused by heterozygous mutations in the CALM1 (Calmodulin 1) gene (114180) on chromosome 14q32.[en.wikipedia.org] LQT16LQT16 is caused by heterozygous mutations in the CALM3 (Calmodulin 3) gene (114183) on chromosome 19q13. LQTS is classified a form of channelopathy.[en.wikipedia.org]

    Missing: Most Patients Have Adult Onset of Symptoms
  • Alcohol Abuse

    NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health. Office of the Surgeon General (US); National Institute on Alcohol Abuse and Alcoholism (US); Substance Abuse and Mental Health Services Administration (US). The Surgeon General's Call to Action To Prevent and Reduce[…][ncbi.nlm.nih.gov]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene
  • Hypoglycemia

    Intern Med. 2016;55(8):949-53. doi: 10.2169/internalmedicine.55.5737. Epub 2016 Apr 15. Author information 1 Department of Endocrinology and Metabolism, Dokkyo Medical University, Japan. Abstract We encountered a 62-year-old woman who experienced frequent episodes of hypoglycemia. She was diagnosed with postprandial[…][ncbi.nlm.nih.gov]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene
  • Glycogen Storage Disease due to Muscle Phosphorylase Kinase Deficiency

    The onset of symptoms can occur in childhood or adulthood; most patients have adult onset.[rarediseases.org] There are autosomal recessive forms of GSD IX (caused by mutations in PHKB, PHKG1, PHKG2, CALM1, CALM2, and CALM3 ), a X-linked liver form (caused by mutations in PHKA2 ),[bmcmedgenet.biomedcentral.com] Notably, some individuals with phosphorylase kinase deficiency in muscle do not have any obvious symptoms.[rarediseases.org]

    Missing: Generalized Motor Seizure
  • Hyponatremia

    […] phenomena. [15] In a complex partial seizure a person may appear confused or dazed and can not respond to questions or direction.[en.wikipedia.org] Focal seizure may become generalized. [15] Jerking activity may start in a specific muscle group and spread to surrounding muscle groups—known as a Jacksonian march. [16][en.wikipedia.org] Focal seizures [ edit ] Focal seizures are often preceded by certain experiences, known as an aura. [12] These may include sensory, visual, psychic, autonomic, olfactory or motor[en.wikipedia.org]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene
  • Chronic Alcoholism

    The concept of "structural plasticity" has emerged as a potential mechanism in neurodegenerative and psychiatric diseases such as drug abuse, depression, and dementia. Chronic alcoholism is a progressive neurodegenerative disease while the person continues to abuse alcohol, though clinical and imaging studies show[…][ncbi.nlm.nih.gov]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene
  • Primary Amebic Meningoencephalitis

    PAM (Case 5) PAM is caused by Naegleria fowleri, with most patients having an acute onset of symptoms with rapid progression and almost always fatal meningoencephalitis within[ajnr.org] The affected patients are children and young adults with no immunologic compromise.[ajnr.org]

    Missing: Mutation in the CALM2 Gene
  • Head Injury

    INTRODUCTION: Head injuries represent a concern in skiing and snowboarding, with traumatic brain injuries being the most common cause of death. AIM: To describe the mechanisms of head and face injuries among World Cup alpine and freestyle skiers and snowboarders. METHODS: We performed a qualitative analysis of[…][ncbi.nlm.nih.gov]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene
  • Alzheimer Disease

    , A M Saunders, D Schmechel, M Pericak-Vance, J Enghild, G S Salvesen, and A D Roses Abstract Apolipoprotein E is immunochemically localized to the senile plaques, vascular amyloid, and neurofibrillary tangles of Alzheimer disease. In vitro, apolipoprotein E in cerebrospinal fluid binds to synthetic beta A4 peptide (the[…][doi.org]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene
  • Alcohol Withdrawal

    The central nervous system controls the brain and spinal cord, and its overactivity can lead to motor seizures and psychological disturbances, including a heightened stress[solutions-recovery.com] Withdrawal seizures Withdrawal seizures (rum fits) occur within 6-48 hours of alcohol cessation; they are major motor seizures that take place during withdrawal in patients[emedicine.medscape.com] According to the National Library of Medicine (NLM), alcohol withdrawal syndrome can generally be broken down according to the timeline below.[solutions-recovery.com]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene