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95 Possible Causes for Generalized Numbness, Pain, Progressive Memory Impairment

  • Traumatic Brain Injury

    The symptoms of CTE may include memory loss, confusion, impaired judgment, impulse control problems, aggression, depression, anxiety, suicidality, parkinsonism (movement symptoms[alz.org] Pain was significantly more intense during tracheal aspiration (p 0.005).[ncbi.nlm.nih.gov] One participant endorsed clinically significant improvements in fatigue and pain severity.[ncbi.nlm.nih.gov]

  • Lyme Disease

    Before diagnosis, there was a progressively increasing onset of multiple symptoms that included attention span impairments, executive dysfunction, sensory hyperacusis, memory[ncbi.nlm.nih.gov] Neuropathic pain is a relatively common outcome of Lyme disease. Pain management options for these patients have been limited to pharmaceutical treatments.[ncbi.nlm.nih.gov] A rash may appear in areas other than the tick bite, and neurological signs such as numbness , tingling, and Bell’s palsy can also occur.[healthline.com]

  • Vitamin B12 Deficiency

    Symptoms include slow mentation, memory impairment, attention deficits and dementia. Optic neuropathy occurs occasionally in adult patient.[ncbi.nlm.nih.gov] […] score of OSDI as a pain determiner and pain frequency measure), tear break up time (TBUT), and Schirmer's type 1 test.[ncbi.nlm.nih.gov] Generalized weakness, impaired memory, depression, numbness and decreased reflexes were more frequently noted in B12 deficient patients, but failed to achieve statistical[ncbi.nlm.nih.gov]

  • Pernicious Anemia

    As the disease progresses, muscle spasms and problems with balance and walking may develop. Memory impairment, tremors, confusion, depression or paranoia may also occur.[livehealthy.chron.com] The tongue may be painful and beefy red. Occasionally, red patches are observed on the edges of the dorsum of the tongue.[emedicine.medscape.com] Vitamin B12 deficiency can result in general symptoms of anemia as well as nerve problems.[labtestsonline.org]

  • Periodontitis

    Therefore, periodontitis could trigger and/or exacerbate an inflammatory condition especially in elderly subjects, leading to memory impairments, contributing to accelerate[doi.org] Differences in general pain intensity between groups were analyzed using the ordinal (linear) chi-square test.[ncbi.nlm.nih.gov] Drainage into a major nerve canal can lead to numbness, which is generally temporary and resolves following successful treatment of the condition.[toothiq.com]

  • Neuralgia

    Furthermore, psychiatric disturbances and the progressive loss of memory and intellectual ability (dementia) can develop.[rarediseases.org] Abstract Neuropathic pain represents a series of relatively uncommon chronic pain conditions, caused by lesions or dysfunctions of peripheral or central afferent pathways[doi.org] These procedures damage your trigeminal nerve fibers, which often causes some degree of facial numbness. This numbness generally does not cause problems.[mountsinai.org]

  • Amyotrophic Lateral Sclerosis

    The memory impairment progressed and AD was diagnosed. Motor impairments developed subsequently and, following additional neurological evaluation, ALS was diagnosed.[ncbi.nlm.nih.gov] The site of pain depends on the pain type or underlying mechanism (eg, painful cramps, nociceptive pain, or neuropathic pain).[ncbi.nlm.nih.gov] Since the disease primarily involves motor neurons, sensory function typically is preserved, although a minority of patients complains of some numbness and paresthesias.[emedicine.medscape.com]

  • Subacute Combined Degeneration of Spinal Cord

    He had been losing the flavor of foods and, in the last month, he presented severe fatigue and rapidly progressive cognitive impairment with memory problems, with episodes[scielo.br] Brain 123:601-619 BoddekeEW (2001) Involvement of chemokines in pain. ‏[books.google.com] People have general weakness, tingling and numbness in the hands and feet, and stiff limbs and may become irritable, drowsy, and confused.[merckmanuals.com]

  • Syringomyelia

    Clinical Features The patient experiences progressive intellectual deterioration beginning with the loss of operational judgment followed by impairment of insight, gradual[intranet.tdmu.edu.ua] Patients with syringomyelia may present with a variety of pain symptoms. It is the site and extension of the syrinx, which determines the character of pain.[ncbi.nlm.nih.gov] It generally causes neurological symptoms ranging from pain to numbness as well as unusual sensations.[house.wikia.com]

  • Thallium Poisoning

    A progressive cerebellar syndrome with impaired ability to coordinate voluntary movements (ataxia) of the arms may also be present.[rarediseases.org] Alopecia and painful neuropathy are its cardinal features, others being gastrointestinal disturbances, encephalopathy, tachycardia, ataxia, hepatorenal and cardiac damage[ncbi.nlm.nih.gov] She described the symptoms perfectly - lethargy, numbness, black-outs, slurred speech, general debility - but she was not the first mystery writer to employ this poison.[independent.co.uk]

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