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2,328 Possible Causes for Generalized Rhythmic Slowing, Muscle Hypotonia, Spasticity - Hyperreflexia

  • Hyponatremia

    They are primarily central nervous system (CNS) manifestations, such as irritability, restlessness, lethargy, muscular twitching, spasticity and hyperreflexia, all of which[]

  • Hydrocephalus

    , hyperreflexia Changes in vital signs resulting from brainstem compression due to herniation Because the fontanelles of infants are still open, the accumulation of CSF can[] […] tone ( hypotonia ) It is important to note that older children and adults with hydrocephalus exhibit different signs and symptoms.[] […] percentile growth chart) Tense fontanelle Setting sun sign : persistent downward deviation of the eyes due to increased ICP in infants and young children Lower extremity spasticity[]

  • Hypoglycemia

    , hepatomegaly with microvesicular fat accumulation, elevated plasma activities of both liver and muscle enzymes, and frequently cerebral edema.[] […] dehydrogenase deficiency) SCAD (short-chain acyl CoA dehydrogenase deficiency Presentation: severe hypoglycemia, hypoketonemia, high plasma free fatty acid concentrations, hypotonia[]

    Missing: Spasticity - Hyperreflexia
  • Lesch Nyhan Syndrome

    In LNS patients there are three major signs of pyramidal dysfunction: spasticity, hyperreflexia and the extensor plantar reflex (also known as the Babinski reflex: the great[] […] tone or soft muscles (hypotonia).[] They also develop signs of pyramidal involvement including spasticity, hyperreflexia, and extensor plantar reflexes.[]

    Missing: Generalized Rhythmic Slowing
  • Myelopathy

    Physical examination commonly elicits long tract signs such as spasticity, hyperreflexia, and abnormal reflexes such as Babinski or Hoffman's sign.[] […] gait," hesitant and jerky) Myelopathic or "upper motor neuron" findings such as spasticity, hyperreflexia, clonus, Babinski, and Hoffman signs, and bowel and bladder dysfunction[] […] and hyperreflexia below the level of the injury level.[]

    Missing: Generalized Rhythmic Slowing
  • Neuromuscular Junction Disorder

    Upper motor neuronal dysfunction lead to spasticity and hyperreflexia while lower motor neuronal lesions lead to paralysis with muscle fasciculations.[] Manifestations include muscle weakness; fasciculation; muscle atrophy; spasm; myokymia; muscle hypertonia, myalgias, and muscle hypotonia.[] These central lesions are most commonly bilateral and may have associated upper motor neuron signs such as spasticity, hyperreflexia, and clonus.[]

    Missing: Generalized Rhythmic Slowing
  • Pelizaeus-Merzbacher Disease

    There is gross spasticity, hyperreflexia and extensor plantar response. In severe cases, the child is unable to sit unsupported and is certainly unable to walk.[] The difficulties with movement can include spasticity (stiff or rigid muscles), hypotonia (floppiness), choreoathetosis (extra movements) and ataxia (unsteadiness/loss of[] hypotonia appears alongside and apart from neurological signs we can mention scoliosis as well.[]

    Missing: Generalized Rhythmic Slowing
  • Early Infantile Epileptic Encephalopathy Type 2

    Spasticity and hyperreflexia are often present but some newborn infants are hypotonic.[] Learning problems (intellectual disabilities), developmental delay, and low muscle tone (hypotonia) are also usually seen in children who have this condition.[] Other signs and symptoms may include intellectual disability, reduced muscle tone ( hypotonia ), hypsarrhythmia (an irregular pattern seen on EEG ), dyskinesia (involuntary[]

    Missing: Generalized Rhythmic Slowing
  • Motor Neuron Disease

    Lower motor neuron (LMN) findings include muscle atrophy and fasciculations, and upper motor neuron (UMN) findings include hyperreflexia, spasticity, muscle spasm, and abnormal[] Loss of lower motor neurons causes denervation atrophy of muscle, manifested by severe hypotonia, weakness, and inability to breathe.[] , hyperreflexia and atrophy in later stages of disease, but fasciculations are absent.[]

    Missing: Generalized Rhythmic Slowing
  • Congenital Muscular Dystrophy

    Paradoxically, some patients have limb spasticity and hyperreflexia with pyramidal signs. No cerebellar signs are present.[] Congenital muscular dystrophy (CMD) comprises a heterogeneous group of disorders with muscle weakness, hypotonia and contractures present at birth.[] Hypotonia means decreased muscle tone. Hypotonia is often a sign of a worrisome problem. The condition can affect children or adults.[]

    Missing: Generalized Rhythmic Slowing

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