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19 Possible Causes for Generalized Sharp-and-Slow-Waves, Hypersalivation, Myoclonic Jerking

  • Panayiotopoulos Syndrome

    EEG showed right occipital high-amplitude sharp and slow-wave complexes followed by brief generalized discharges of slow waves.[] The seizures included mainly autonomic symptoms such as nausea, vomiting, pallor, mydriasis, urinary and fecal incontinence, and rarely hypersalivation.[] […] seizures: loss of consciousness with severe, rhythmic myoclonic jerks.  Myoclonias are bilateral and rhythmic, maximally involving proximal limb muscles, and may be associated[]

  • Lennox-Gastaut Syndrome

    .: Generalized sharp and slow wave complexes associated clinical features and long-term follow-up. Brain, 1973, 96: 289–306.[] Mood changes, sedation, ataxia, and hypersalivation, well-known complications of other AEDs, were not observed.[] In such cases, massive myoclonic jerks, myoclonic-atonic attacks, as well as atonic seizures may occur, though much less frequent and severe than the other manifestations.[]

  • Epilepsy

    sharp waves and sharp waves-slow waves; paroxysmal fast activity Neurological examination mild diffuse hypotonia, mild ataxia with wide based gait, mild tremor general hypotonia[] So the jerks were considered as cortical origin and generalized myoclonic seizure was confirmed.[] , like EPC, presented with myoclonic jerks. [7] This thought process was later proven inconclusive after considering subsequent literature.[]

  • Rolandic Epilepsy

    I think abnormal brain activity can be associted with weird sleep like myoclonic jerks or sleeping with eyes open.[] Hypersalivation is not just frothing: Suddenly my mouth is full of saliva, it runs out like a river and I cannot speak.[] […] of infancy In a subgroup of patients, myoclonic jerks may be triggered by tactile or sudden acoustic stimuli, referred to as reflex benign myoclonic epilepsy of infancy.[]

  • Early Infantile Epileptic Encephalopathy Type 6

    When present, they consist of spikes, single and multiple spike-waves, generalized, symmetric or asymmetric, isolated or in brief bursts, and of localized sharp waves, slow[] As the affected children grow up, they develop myoclonic jerking, and their seizures may become refractory to treatment. Synonym: severe myoclonic epilepsy of infancy[] sharp waves or spikes in 80% of patients (4/5), with occipital predominance in one and frontal in two.[]

  • Epilepsia Partialis Continua

    Various EEG changes have been described in HIV sero-positive patients including sharp waves, spikes, focal, and generalized slowing (Gabuzada et al 10 and Kellinghaus et al[] We used electroencephalographic (EEG) dipole analysis to investigate the generators of spikes with and without myoclonic jerks in a 12-year-old patient with epilepsia partialis[] An opercular syndrome was diagnosed based on the classic presentation of dysarthria, facial diplegia, and hypersalivation, with corresponding MRI brain changes in the operculum[]

  • Benign Familial Infantile Epilepsy Type 4

    The abnormal EEG findings that are most likely to correlate with clinical seizures include spikes or sharp waves, with or without concomitant slow waves, that are generalized[] Studies using video-EEG recordings have demonstrated that the myoclonic jerks involve the axis of the body and the arms, provoking a head drop, and commonly result in an upward[] Less often, miosis, hypersalivation, and bladder incontinence occur.[]

  • Postictal State

    EEG may detect epileptiform abnormalities (spikes, sharp waves, spike and slow-wave complexes, polyspike and slow-wave complexes).[] Thus, myoclonic jerks occurring in the context of typical absence seizures do not worsen the prognosis. [4] Other distinct absence syndromes with a prominent myoclonic component[] […] rhythmic muscle twitching) Bladder or bowel incontinence Tongue bite lacerations Unresponsiveness Confusion Amnesia Aphasia Fatigue Muscular flaccidity and muscle pain Headache Hypersalivation[]

  • X-linked Parkinsonism-Spasticity Syndrome

    […] low uptake on SPECT/PET perfusion scan with reduced occipital activity  Abnormal (low uptake) MIBG myocardial scintigraphy  Prominent slow wave activity on EEG with temporal[] Physiologic myoclonus is often normal in people, for example myoclonic jerks during sleep transitions.[] Migraine headaches not sufficiently treated by oral medications; myofascial pain syndrome Spasms and limb spasticity (from stroke, multiple sclerosis, spinal cord injury, etc) Hypersalivation[]

  • Atonic Seizures

    The EEG showed generalized sharp and slow waves dominant in central and midtemporal area, which became continuous as she fell in sleep.[] Ethosuximide (absences) and clonazepam (myoclonic jerks) may be useful.[] […] rhythmic muscle twitching) Bladder or bowel incontinence Tongue bite lacerations Unresponsiveness Confusion Amnesia Aphasia Fatigue Muscular flaccidity and muscle pain Headache Hypersalivation[]