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77 Possible Causes for Generalized Slow Activity Grade 3, Most Patients Have Adult Onset of Symptoms, Mutation in the CALM2 Gene

  • Meningoencephalitis

    PAM (Case 5) PAM is caused by Naegleria fowleri, with most patients having an acute onset of symptoms with rapid progression and almost always fatal meningoencephalitis within[ajnr.org] The affected patients are children and young adults with no immunologic compromise.[ajnr.org]

    Missing: Mutation in the CALM2 Gene
  • Hypoglycemia

    A 61-year-old woman with multiple metastatic and unresectable gastrointestinal stromal tumors (GISTs) was referred for investigation of refractory hypoglycemia that developed four months before this hospitalization. On admission, her fasting plasma glucose was 38 mg/dL despite 10% glucose infusion. Investigations[…][ncbi.nlm.nih.gov]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene
  • Glycogen Storage Disease due to Muscle Phosphorylase Kinase Deficiency

    The onset of symptoms can occur in childhood or adulthood; most patients have adult onset.[rarediseases.org] There are autosomal recessive forms of GSD IX (caused by mutations in PHKB, PHKG1, PHKG2, CALM1, CALM2, and CALM3 ), a X-linked liver form (caused by mutations in PHKA2 ),[bmcmedgenet.biomedcentral.com] Notably, some individuals with phosphorylase kinase deficiency in muscle do not have any obvious symptoms.[rarediseases.org]

    Missing: Generalized Slow Activity Grade 3
  • Hyponatremia

    Clin J Am Soc Nephrol. 2011 May; 6(5): 960–965. Original Articles See commentary on page 951. This article has been cited by other articles in PMC. Abstract Summary Background and objectives Severe hyponatremia ( Design, setting, participants, & measurements The relationship between mortality and serum sodium (sNa)[…][ncbi.nlm.nih.gov]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene
  • Alzheimer Disease

    Alzheimer's disease (AD) related genes have been elucidated by advanced genetic techniques. Familial autosomal dominant AD genes founded by linkage analyses are APP, PSEN1, PSEN2, ABCA7, and SORL1. Genome-wide association studies have found risk genes such as ABCA7, BIN1, CASS4, CD33, CD2AP, CELF1, CLU, CR1, DSG2,[…][ncbi.nlm.nih.gov]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene
  • Traumatic Brain Injury

    Objectives: This critical literature review examines historical and current investigations on the efficacy and mechanisms of hyperbaric oxygen (HBO) treatment in traumatic brain injury (TBI). Potential safety risks and oxygen toxicity, as well as HBO's future potential, are also discussed. Methods: Directed literature[…][oadoi.org]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene
  • Stroke

    The Rational Clinical Examination Clinician's Corner May 18, 2005 JAMA. 2005;293(19):2391-2402. doi:10.1001/jama.293.19.2391 Context Patients suspected of having a stroke or transient ischemic attack require accurate assessment for appropriate acute treatment and use of secondary preventive interventions. Objective[…][oadoi.org]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene
  • Dementia

    † Deceased. From University of Minnesota, Minneapolis, Minnesota; Brown University, Providence, Rhode Island; and Minneapolis VA Health Care System and HealthPartners, Minneapolis, Minnesota. Disclaimer: Findings and conclusions are those of the authors, who are responsible for the article's contents; findings and[…][doi.org]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene
  • Cushing Syndrome

    In the setting of Cushing syndrome, genomic analyses can be performed either in tumors responsible for endogenous Cushing, or in patients exposed to glucocorticoid excess. Genomics of tumors identified several new genes - including ZNRF3 in adrenocortical carcinomas, PRKACA in cortisol-producing adrenal adenomas,[…][ncbi.nlm.nih.gov]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene
  • Hydrocephalus

     To demonstrate the change of the ascending reticular activating system (ARAS) concurrent with the recovery of impaired consciousness following a shunt operation in a stroke patient.  A 65-year-old female patient underwent coiling of a ruptured right posterior communicating artery and, subsequently, underwent[…][ncbi.nlm.nih.gov]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene