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498 Possible Causes for Generalized Spike-and-Slow-Waves, Mild Cerebellar Hypoplasia, Polyspike-and-Slow-Waves

  • Benign Adult Familial Myoclonic Epilepsy

    , high-amplitude spike and slow-wave complexes 3.5 Hz, typically 4 s duration.  Absence seizures in JAE are more sporadic.  EEG is slightly faster with generalized spike[slideshare.net] hypoplasia-hydranencephaly syndrome Multiple acyl-CoA dehydrogenase deficiency Multiple acyl-CoA dehydrogenase deficiency, mild type Multiple acyl-CoA dehydrogenase deficiency[orpha.net] Electrophysiological findings reveal giant SSEP and EEG shows general spikes or polyspikes and slow wave complexes. The gene is mapped at chromosome 8q24.[neuroweb.us]

  • West Syndrome

    Lennox-Gastaut Syndrome: LGS is characterized by multiple types of seizures and an abnormal EEG with generalized slow spikewave discharges.[cdkl5.com] Interictal The background EEG is often highly disorganized with high voltage irregular slow waves intermixed with multifocal spikes and polyspikes, this is termed 'hypsarrhythmia[epilepsydiagnosis.org] Magnetic resonance imaging of the brain revealed mild cerebral and cerebellar atrophy, high-signal-intensity areas in the white matter, and hypoplasia of the corpus callosum[ncbi.nlm.nih.gov]

  • Epilepsy

    Electroencephalography (EEG) showed progressively slowed background activity and sporadic generalized spike-and-wave discharges.[ncbi.nlm.nih.gov] Generalized polyspike-slow wave in EEG was common to see in myoclonic seizure and can help to make the classification.[ncbi.nlm.nih.gov] […] predominance, and multifocal spike-and-slow waves.[ncbi.nlm.nih.gov]

    Missing: Mild Cerebellar Hypoplasia
  • Juvenile Myoclonic Epilepsy

    […] multiple spike and spike slow wave discharges (in an untreated patient).8 The possible factors responsible for the delay in the diagnosis of JME were studied retrospectively[neurologyindia.com] Additionally, an electroencephalogram (EEG), will indicate a characteristic pattern of waves and spikes associated with the syndrome such as generalized 4–6 Hz polyspike and[en.wikipedia.org] The EEG typically shows a characteristic pattern with generalized 4–6 Hz polyspike and slow wave discharges .[medindia.net]

    Missing: Mild Cerebellar Hypoplasia
  • Generalized Clonic or Tonic-Clonic Seizures

    , poly spike discharges." [2] The clonic phase EEG will show "high amplitude activity that is typically interrrupted by slow waves to create a spike-and-slow-wave pattern.[en.wikipedia.org] . • Ictal EEG consists of “Fast activity” (10 Hz or more) and slow waves, with an occasional spike-and-wave pattern. • The EEG interictal expression is of “spike-and-wave[medlink.com] According to "Harrisons Manual of Medicine," the EEG during the tonic phase will show a "progressive increase in low-voltage fast wave activity, followed by generalized high-amplitude[en.wikipedia.org]

    Missing: Mild Cerebellar Hypoplasia
  • Myoclonic-Astatic Epilepsy

    The interictal EEG revealed frequent bursts of generalized 100-200 μV, 2-4 Hz spike-and-slow-wave complexes.[ncbi.nlm.nih.gov] Ictal EEG Myoclonic and atonic seizures discharges of irregular spike-waves or polyspike-waves at 2.5 to 3 Hz or more.[epilepsy.com] In the former, EDA were caused by epileptic spasms (ES) corresponding to generalized biphasic slow discharges, sharp-and-slow wave complexes, or the flattening of ongoing[ncbi.nlm.nih.gov]

    Missing: Mild Cerebellar Hypoplasia
  • Juvenile Absence Epilepsy

    All patients had minimum twice EEG recordings and all had typical 3-Hz generalized spike and slow-wave discharges at least on one EEG.[ncbi.nlm.nih.gov] The EEG has generalized spike or polyspike slow-wave complexes. JAE is a lifelong disorder, although seizures can be controlled in 70% to 80% of patients.[pennsw.com.au] EEG shows classical generalized 3 Hz spike-and-slow-wave discharges.[medlink.com]

    Missing: Mild Cerebellar Hypoplasia
  • Idiopathic Generalized Epilepsy

    […] epilepsy K complex lambda mu OIRDA PLEDs phantom spike and wave photic driving photoparoxysmal response photomyogenic artifact poly spike and wave posterior dominant rhythm[eegatlas-online.com] […] and waves with frontocentral predominance Interictal EEG : 4–6 Hz bilateral polyspike and slow wave Responds well to antiseizure drug therapy; seizures become less frequent[amboss.com] The morphology of the focal spike-and-wave typically appears similar to the generalized spike-and-wave. Ictal.[medlink.com]

    Missing: Mild Cerebellar Hypoplasia
  • Lennox-Gastaut Syndrome

    The semiology of seizures progressively changed to generalized episodes of hypertonia and myoclonus, with slow spike-wave electroencephalographic activity.[ncbi.nlm.nih.gov] […] that are more generalized and more frequent, consisting of polyspikes and slow waves REM sleep – Decreased spike waves Ictal EEG may demonstrate the following characteristics[emedicine.medscape.com] Lennox-Gastaut syndrome (LGS) is a childhood epileptic encephalopathy characterized by an electroclinical triad of generalized slow spike wave (SSW) activity in the EEG, multiple[ncbi.nlm.nih.gov]

    Missing: Mild Cerebellar Hypoplasia
  • Early Infantile Epileptic Encephalopathy Type 3

    EEG demonstrates primarily burst-suppression patterns in the neonatal period, hypsarrhythmia in infancy, and slow generalized spike-wave discharges in early childhood.[fortheloveofbubbe.weebly.com] […] paroxysms of polyspikes or spikes-slow waves.  Ictal EEG  Varies according to seizure type. 16.[slideshare.net] slow spike-and-wave discharges Affected LGS patients have different degrees of developmental delay and they often develop autism and intellectual disability 43 Patients react[centogene.com]

    Missing: Mild Cerebellar Hypoplasia

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