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478 Possible Causes for Generalized Spike-and-Slow-Waves, Mild Cerebellar Hypoplasia, Polyspike on Photic Stimulation

  • Benign Adult Familial Myoclonic Epilepsy

    , high-amplitude spike and slow-wave complexes 3.5 Hz, typically 4 s duration.  Absence seizures in JAE are more sporadic.  EEG is slightly faster with generalized spike[slideshare.net] Photic stimulation and hyperventilation were performed in all. RESULTS: Nineteen (eight men, 11 women) patients with BAFME were included in this study.[ncbi.nlm.nih.gov] hypoplasia-hydranencephaly syndrome Multiple acyl-CoA dehydrogenase deficiency Multiple acyl-CoA dehydrogenase deficiency, mild type Multiple acyl-CoA dehydrogenase deficiency[orpha.net]

  • West Syndrome

    Lennox-Gastaut Syndrome: LGS is characterized by multiple types of seizures and an abnormal EEG with generalized slow spikewave discharges.[cdkl5.com] Magnetic resonance imaging of the brain revealed mild cerebral and cerebellar atrophy, high-signal-intensity areas in the white matter, and hypoplasia of the corpus callosum[ncbi.nlm.nih.gov] Interictal EEG displays diffuse and asynchronous high voltage spikes and slow waves suggesting the hypsarrhythmic pattern. B.[bmcneurol.biomedcentral.com]

  • Juvenile Myoclonic Epilepsy

    […] multiple spike and spike slow wave discharges (in an untreated patient).8 The possible factors responsible for the delay in the diagnosis of JME were studied retrospectively[neurologyindia.com] Two cases of juvenile myoclonic epilepsy (JME) presented with myoclonic jerks and EEG activation after eye closure, without sensitivity to intermittent photic stimulation.[ncbi.nlm.nih.gov] slow wave discharges.[en.wikipedia.org]

    Missing: Mild Cerebellar Hypoplasia
  • Generalized Clonic or Tonic-Clonic Seizures

    , poly spike discharges." [2] The clonic phase EEG will show "high amplitude activity that is typically interrrupted by slow waves to create a spike-and-slow-wave pattern.[en.wikipedia.org] Specific EEG changes may be seen during photic stimulation. EEG abnormalities are more likely or increased with sleep deprivation and during sleep.[epilepsy.com] According to "Harrisons Manual of Medicine," the EEG during the tonic phase will show a "progressive increase in low-voltage fast wave activity, followed by generalized high-amplitude[en.wikipedia.org]

    Missing: Mild Cerebellar Hypoplasia
  • Epilepsy

    Electroencephalography (EEG) showed progressively slowed background activity and sporadic generalized spike-and-wave discharges.[ncbi.nlm.nih.gov] Neuroimaging studies were unremarkable and electroencephalograms showed high voltage 200-400uV, 2-2.5 Hz generalized spike-and-waves and polyspikes with alternating frontal[ncbi.nlm.nih.gov] […] specified generalized (poly)spike waves, slow spike waves, multifocal discharges, generalized paroxysmal fast activity, diffuse slowing slow background, generalized spike[ncbi.nlm.nih.gov]

    Missing: Mild Cerebellar Hypoplasia
  • Myoclonic-Astatic Epilepsy

    The interictal EEG revealed frequent bursts of generalized 100-200 μV, 2-4 Hz spike-and-slow-wave complexes.[ncbi.nlm.nih.gov] Photic stimulation may trigger generalised spike/wave or myoclonic astatic seizures.[pennsw.com.au] Intermittent photic stimulation may trigger generalized spike-and-wave and polyspike-and-wave, and myoclonic-atonic seizures.[medlink.com]

    Missing: Mild Cerebellar Hypoplasia
  • Idiopathic Generalized Epilepsy

    […] epilepsy K complex lambda mu OIRDA PLEDs phantom spike and wave photic driving photoparoxysmal response photomyogenic artifact poly spike and wave posterior dominant rhythm[eegatlas-online.com] These discharges are often precipitated by hyperventilation, sleep deprivation, and intermittent photic stimulation (IPS).[epilepsy.com] The morphology of the focal spike-and-wave typically appears similar to the generalized spike-and-wave. Ictal.[medlink.com]

    Missing: Mild Cerebellar Hypoplasia
  • Juvenile Absence Epilepsy

    All patients had minimum twice EEG recordings and all had typical 3-Hz generalized spike and slow-wave discharges at least on one EEG.[ncbi.nlm.nih.gov] However, on EEG, intermittent photic stimulation often facilitates generalized discharges and absences.[medlink.com] The EEG has generalized spike or polyspike slow-wave complexes. JAE is a lifelong disorder, although seizures can be controlled in 70% to 80% of patients.[pennsw.com.au]

    Missing: Mild Cerebellar Hypoplasia
  • Lennox-Gastaut Syndrome

    The semiology of seizures progressively changed to generalized episodes of hypertonia and myoclonus, with slow spike-wave electroencephalographic activity.[ncbi.nlm.nih.gov] Lennox-Gastaut syndrome (LGS) is a childhood epileptic encephalopathy characterized by an electroclinical triad of generalized slow spike wave (SSW) activity in the EEG, multiple[ncbi.nlm.nih.gov] slow spike wave (SSW) activity in the EEG, multiple types of epileptic seizures, and slow mental development.[doi.org]

    Missing: Mild Cerebellar Hypoplasia
  • Unverricht-Lundborg Syndrome

    Slow ( 2.5 Hz) electroencephalographic spike and wave discharges in atypical absence epilepsy (ie, Lennox-Gastaut syndrome). Spike, generalized.[emedicine.medscape.com] There are generalized polyspike discharges at rest that are exacerbated by photic stimulation. Fig. 2 EEG of individual V-13 at age 35 years.[academic.oup.com] hypoplasia-hydranencephaly syndrome Multiple acyl-CoA dehydrogenase deficiency Multiple acyl-CoA dehydrogenase deficiency, mild type Multiple acyl-CoA dehydrogenase deficiency[orpha.net]

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