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476 Possible Causes for Generalized Spike-and-Slow-Waves, Mild Cerebellar Hypoplasia, Slow-Frequency High-Amplitude Waves with High-Frequency Polyspikes

  • Benign Adult Familial Myoclonic Epilepsy

    , high-amplitude spike and slow-wave complexes 3.5 Hz, typically 4 s duration.  Absence seizures in JAE are more sporadic.  EEG is slightly faster with generalized spike[slideshare.net] hypoplasia-hydranencephaly syndrome Multiple acyl-CoA dehydrogenase deficiency Multiple acyl-CoA dehydrogenase deficiency, mild type Multiple acyl-CoA dehydrogenase deficiency[orpha.net] Generalized slow spikes and waves may be present as an interictal pattern, as in Lennox-Gastaut syndrome.[reference.medscape.com]

  • West Syndrome

    Lennox-Gastaut Syndrome: LGS is characterized by multiple types of seizures and an abnormal EEG with generalized slow spikewave discharges.[cdkl5.com] Magnetic resonance imaging of the brain revealed mild cerebral and cerebellar atrophy, high-signal-intensity areas in the white matter, and hypoplasia of the corpus callosum[ncbi.nlm.nih.gov] Interictal EEG displays diffuse and asynchronous high voltage spikes and slow waves suggesting the hypsarrhythmic pattern. B.[bmcneurol.biomedcentral.com]

  • Epilepsy

    Electroencephalography (EEG) showed progressively slowed background activity and sporadic generalized spike-and-wave discharges.[ncbi.nlm.nih.gov] Neuroimaging studies were unremarkable and electroencephalograms showed high voltage 200-400uV, 2-2.5 Hz generalized spike-and-waves and polyspikes with alternating frontal[ncbi.nlm.nih.gov] […] specified generalized (poly)spike waves, slow spike waves, multifocal discharges, generalized paroxysmal fast activity, diffuse slowing slow background, generalized spike[ncbi.nlm.nih.gov]

    Missing: Mild Cerebellar Hypoplasia
  • Generalized Clonic or Tonic-Clonic Seizures

    , poly spike discharges." [2] The clonic phase EEG will show "high amplitude activity that is typically interrrupted by slow waves to create a spike-and-slow-wave pattern.[en.wikipedia.org] According to "Harrisons Manual of Medicine," the EEG during the tonic phase will show a "progressive increase in low-voltage fast wave activity, followed by generalized high-amplitude[en.wikipedia.org]

    Missing: Mild Cerebellar Hypoplasia
  • Juvenile Myoclonic Epilepsy

    […] multiple spike and spike slow wave discharges (in an untreated patient).8 The possible factors responsible for the delay in the diagnosis of JME were studied retrospectively[neurologyindia.com] slow wave discharges.[en.wikipedia.org] […] high frequency (10-16 Hz) spikes, usually followed by slow waves in a frequency of 2,5-5Hz [ 8 ].[omicsonline.org]

    Missing: Mild Cerebellar Hypoplasia
  • Myoclonic-Astatic Epilepsy

    The interictal EEG revealed frequent bursts of generalized 100-200 μV, 2-4 Hz spike-and-slow-wave complexes.[ncbi.nlm.nih.gov] In the former, EDA were caused by epileptic spasms (ES) corresponding to generalized biphasic slow discharges, sharp-and-slow wave complexes, or the flattening of ongoing[ncbi.nlm.nih.gov] The morphology of the focal spike-and-wave typically appears similar to the generalized spike-and-wave. Ictal.[medlink.com]

    Missing: Mild Cerebellar Hypoplasia
  • Idiopathic Generalized Epilepsy

    […] epilepsy K complex lambda mu OIRDA PLEDs phantom spike and wave photic driving photoparoxysmal response photomyogenic artifact poly spike and wave posterior dominant rhythm[eegatlas-online.com] The morphology of the focal spike-and-wave typically appears similar to the generalized spike-and-wave. Ictal.[medlink.com] Initial EEG shows generalized bursts of high amplitude spikes and slow waves in (a) spontaneous record, (b) hyperventilation, (c) post-hyperventilation, (d) photic stimulation[annalsofian.org]

    Missing: Mild Cerebellar Hypoplasia
  • Juvenile Absence Epilepsy

    All patients had minimum twice EEG recordings and all had typical 3-Hz generalized spike and slow-wave discharges at least on one EEG.[ncbi.nlm.nih.gov] EEG shows classical generalized 3 Hz spike-and-slow-wave discharges.[medlink.com] The EEG has generalized spike or polyspike slow-wave complexes. JAE is a lifelong disorder, although seizures can be controlled in 70% to 80% of patients.[pennsw.com.au]

    Missing: Mild Cerebellar Hypoplasia
  • Lennox-Gastaut Syndrome

    The semiology of seizures progressively changed to generalized episodes of hypertonia and myoclonus, with slow spike-wave electroencephalographic activity.[ncbi.nlm.nih.gov] Lennox-Gastaut syndrome (LGS) is a childhood epileptic encephalopathy characterized by an electroclinical triad of generalized slow spike wave (SSW) activity in the EEG, multiple[ncbi.nlm.nih.gov] slow spike wave (SSW) activity in the EEG, multiple types of epileptic seizures, and slow mental development.[doi.org]

    Missing: Mild Cerebellar Hypoplasia
  • Early Infantile Epileptic Encephalopathy Type 3

    EEG demonstrates primarily burst-suppression patterns in the neonatal period, hypsarrhythmia in infancy, and slow generalized spike-wave discharges in early childhood.[fortheloveofbubbe.weebly.com] slow spike-and-wave discharges Affected LGS patients have different degrees of developmental delay and they often develop autism and intellectual disability 43 Patients react[centogene.com] The EEG pattern often shows a suppression-burst pattern with high-voltage bursts of slow waves mixed with multifocal spikes alternating with isoelectric suppression phases[diseaseinfosearch.org]

    Missing: Mild Cerebellar Hypoplasia

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