Create issue ticket

94 Possible Causes for Genetic Heterogeneity, Polyspike-and-Slow-Waves

  • Benign Adult Familial Myoclonic Epilepsy

    […] or polyspike and slow-wave complexes.  Variable course and outcome.  One half experience encephalopathic effects and suffer from persistent GTCS, myoclonic-atonic status[slideshare.net] Abstract Benign adult familial myoclonic epilepsy (BAFME) has been mapped to chromosome 8q24; however, genetic heterogeneity has been recently suggested.[ncbi.nlm.nih.gov] This observation would confirm that BAFME is a worldwide, genetically heterogeneous condition, probably with Japanese families linked to 8q24 and European families to 2p11.1[ncbi.nlm.nih.gov]

  • Juvenile Myoclonic Epilepsy

    slow wave discharges.[en.wikipedia.org] BACKGROUND: Juvenile myoclonic epilepsy (JME), is an early-onset inherited generalized epilepsy which displays genetic heterogeneity, with at least 10 known loci.[ncbi.nlm.nih.gov] Abstract Juvenile myoclonic epilepsy (JME) is a clinically and genetically heterogenous, generalized epilepsy syndrome usually starting in adolescence.[ncbi.nlm.nih.gov]

  • Idiopathic Generalized Epilepsy

    […] and waves with frontocentral predominance Interictal EEG : 4–6 Hz bilateral polyspike and slow wave Responds well to antiseizure drug therapy; seizures become less frequent[amboss.com] The lack of significant association evidence of single variants with disease in this two-stage approach emphasizes the high genetic heterogeneity of epilepsy disorders, suggests[ncbi.nlm.nih.gov] Molecular genetic analyses have led to important breakthroughs in the identification of candidate genes and loci; genetic heterogeneity is common.[epilepsy.com]

  • Epilepsy

    Generalized polyspike-slow wave in EEG was common to see in myoclonic seizure and can help to make the classification.[ncbi.nlm.nih.gov] Progressive myoclonic epilepsies (PME) are a clinically and genetically heterogeneous group of rare diseases characterized by myoclonic seizures, tonic-clonic seizures, and[ncbi.nlm.nih.gov] […] predominance, and multifocal spike-and-slow waves.[ncbi.nlm.nih.gov]

  • Myoclonic-Astatic Epilepsy

    Ictal EEG Myoclonic and atonic seizures discharges of irregular spike-waves or polyspike-waves at 2.5 to 3 Hz or more.[epilepsy.com] […] influences and clues for genetic heterogeneity, and discuss strategies that may be helpful in elucidating the etiology of MAE in light of current genetic techniques.[ncbi.nlm.nih.gov] Doose Syndrome is likely to be genetically heterogeneous and – in contrast to Dravet Syndrome – caused by various different genes.[epilepsygenetics.net]

  • Generalized Clonic or Tonic-Clonic Seizures

    . • Ictal EEG consists of “Fast activity” (10 Hz or more) and slow waves, with an occasional spike-and-wave pattern. • The EEG interictal expression is of “spike-and-wave[medlink.com] Genetic Heterogeneity of Progressive Myoclonic EpilepsyProgressive myoclonic epilepsy refers to a clinically and genetically heterogeneous group of neurodegenerative disorders[mendelian.co] Genetic Heterogeneity of Mosaic Variegated Aneuploidy SyndromeSee also MVA2 ( OMIM ), caused by mutation in the CEP57 gene ( OMIM ) on chromosome 11q21, and MVA3 ( OMIM ),[mendelian.co]

  • West Syndrome

    Interictal The background EEG is often highly disorganized with high voltage irregular slow waves intermixed with multifocal spikes and polyspikes, this is termed 'hypsarrhythmia[epilepsydiagnosis.org] West syndrome is genetically heterogeneous, and its genetic causes have not been fully elucidated.[ncbi.nlm.nih.gov] This disorder is genetically heterogeneous, with up to a fifth of cases resulting from mutations in the CDKL5 gene.[genedx.com]

  • Juvenile Absence Epilepsy

    The EEG has generalized spike or polyspike slow-wave complexes. JAE is a lifelong disorder, although seizures can be controlled in 70% to 80% of patients.[pennsw.com.au] Página 112 - JC (1998) Autosomal dominant nocturnal frontal-lobe epilepsy: genetic heterogeneity and evidence for a second locus at 15q24. Am. J. Hum.[books.google.es] […] and waves with frontocentral predominance Interictal EEG : 4–6 Hz bilateral polyspike and slow wave Responds well to antiseizure drug therapy; seizures become less frequent[amboss.com]

  • Early Infantile Epileptic Encephalopathy Type 17

    EEG recordings showed a variety of changes: generalized spike wave and polyspike wave activity, focal discharges, focal or diffuse slowing or were normal.[dx.doi.org] […] background resulting in intrafamilial clinical heterogeneity for these mutations.[ncbi.nlm.nih.gov] Catalina Betancur, Etiological heterogeneity in autism spectrum disorders: More than 100 genetic and genomic disorders and still counting, Brain Research, 10.1016/j.brainres[dx.doi.org]

  • Myoclonic Jerking

    Ictal EEG : The myoclonic component is associated with a generalized spike or polyspike. The atonic component is associated with the aftergoing high voltage slow wave.[medlink.com] Paroxysmal exercise induced dyskinesia Paroxysmal exercise induced dyskinesia represents a genetically heterogenous group of conditions in which dystonia or choreoathetosis[epilepsydiagnosis.org]

Further symptoms

Similar symptoms