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1,864 Possible Causes for Genu Valgum, Magnesium Decreased, Some Patients May Be Clinically Asymptomatic

  • Vitamin D Deficiency

    It is imperative to consider that some patients, such as our patient described in this report, may be previously asymptomatic clinically and on the basis of laboratory findings[ncbi.nlm.nih.gov] However, severe vitamin D deficiency may manifest as rickets with the below clinical features: Bony Signs - Swelling of wrists and ankles - Leg deformities (genu varum or[starship.org.nz] Simin Liu and Qing Liu, Personalized magnesium intervention to improve vitamin D metabolism: applying a systems approach for precision nutrition in large randomized trials[doi.org]

  • Primary Hyperparathyroidism

    It is imperative to consider that some patients, such as our patient described in this report, may be previously asymptomatic clinically and on the basis of laboratory findings[ncbi.nlm.nih.gov] On examination she had bilateral genu valgum.[ncbi.nlm.nih.gov] Even asymptomatic PHPT patients display clinical improvement in some symptoms a year following PTx, particularly patients with higher preoperative calcium levels ( 2.6 mmol[link.springer.com]

  • Hypophosphatemia

    The absence of short stature and lower limb deformities in some of these patients suggest a not so intense hypophosphatemia during infancy and childhood (53).[scielo.br] In infants and children, the signs and symptoms include: Abnormal "waddling" walk due to knock-knees (genu valgum) or bowed legs (genu varum) Thick wrists Ribs of the chest[dovemed.com] However, in our case, inappropriate phosphaturia persisted during hospitalization, even when the magnesium balance was restored.[joplink.net]

  • Osteomalacia

    The absence of short stature and lower limb deformities in some of these patients suggest a not so intense hypophosphatemia during infancy and childhood (53).[scielo.br] Bowing of the legs (genu varum) is typical, but knock knees (genu valgum) can also occur.[patient.info] One relevant point is that phosphatemia decreases progressively with age.[scielo.br]

  • Diarrhea

    Some patients with celiac disease may remain asymptomatic or have only mild gastrointestinal symptoms and thus may qualify for the diagnosis of IBS in the general clinical[dx.doi.org]

    Missing: Genu Valgum
  • Chronic Pyelonephritis

    Some patients may be asymptomatic while others may present with malaise, fatigue, loss of appetite, loss of weight, cloudy urine, fever, backache, flank pain, or abdominal[symptoma.com] The clinical presentation of CP is variable and non-specific.[symptoma.com]

    Missing: Genu Valgum
  • Marfan Syndrome

    Ionic calcium is antagonized by magnesium ions in the nervous system.[en.wikipedia.org] However, because dihydropyridine CCBs result in a decrease in blood pressure, the baroreceptor reflex often initiates a reflexive increase in sympathetic activity leading[en.wikipedia.org]

    Missing: Some Patients May Be Clinically Asymptomatic
  • Viral Hepatitis

    patients with cirrhosis are asymptomatic, others develop life-threatening complications.[emedicine.medscape.com] The clinical illnesses of chronic hepatitis and cirrhosis may take months, years, or decades to evolve.[emedicine.medscape.com] Perz et al estimated that 57% of cirrhosis and 78% of hepatocellular carcinoma worldwide was attributable to chronic infection with either hepatitis B or C. [8] Although some[emedicine.medscape.com]

    Missing: Genu Valgum
  • Celiac Disease

    Some patients are asymptomatic or have only signs of nutritional deficiency. Others have significant GI symptoms.[merckmanuals.com] Some adult evidence to suggest that despite following a strict gluten free diet and normalization of anti tTG, in some patients, intestinal histology may still exhibit persistent[clinicaladvisor.com] Onset is generally in childhood but may occur later. Symptoms and Signs The clinical presentation varies; no typical presentation exists.[merckmanuals.com]

    Missing: Genu Valgum
  • Acute Hepatic Porphyria

    Some display an asymptomatic clinical pattern, while others may present with acute or sub-acute chronic symptoms.[signavitae.com] In AIP patients with chronic high excretion, the ratio is approximately 2.0.[signavitae.com] Patients presenting with acute crises often have several-fold increases in PBG above the reference interval, usually 10 times the upper reference limit.[signavitae.com]

    Missing: Genu Valgum

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