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16 Possible Causes for Genu Valgum, Nausea, Some Patients May Be Clinically Asymptomatic

  • Vitamin D Deficiency

    It is imperative to consider that some patients, such as our patient described in this report, may be previously asymptomatic clinically and on the basis of laboratory findings[ncbi.nlm.nih.gov] Symptoms of vitamin D toxicity include nausea, vomiting and weakness.[parentgiving.com] However, severe vitamin D deficiency may manifest as rickets with the below clinical features: Bony Signs - Swelling of wrists and ankles - Leg deformities (genu varum or[starship.org.nz]

  • Primary Hyperparathyroidism

    It is imperative to consider that some patients, such as our patient described in this report, may be previously asymptomatic clinically and on the basis of laboratory findings[ncbi.nlm.nih.gov] A 46 year-old female patient presented to the hospital with ongoing and progressively increasing fatigue, severe nausea and vomiting, loss of appetite, constipation, palpitations[ncbi.nlm.nih.gov] On examination she had bilateral genu valgum.[ncbi.nlm.nih.gov]

  • Hypophosphatemia

    The absence of short stature and lower limb deformities in some of these patients suggest a not so intense hypophosphatemia during infancy and childhood (53).[scielo.br] Side effects include diarrhea, which is often dose-limiting, and nausea.[enotes.tripod.com] In infants and children, the signs and symptoms include: Abnormal "waddling" walk due to knock-knees (genu valgum) or bowed legs (genu varum) Thick wrists Ribs of the chest[dovemed.com]

  • Osteomalacia

    The absence of short stature and lower limb deformities in some of these patients suggest a not so intense hypophosphatemia during infancy and childhood (53).[scielo.br] In young children - poor sleep, restlessness, headache, nausea, dizziness, nervousness, diarrhea.[specialityclinic.com] Bowing of the legs (genu varum) is typical, but knock knees (genu valgum) can also occur.[patient.info]

  • Glycogen Storage Disease due to Glucose-6-Phosphat Transport Defect

    Related to Increased sarcoplasmic Ca Myalgia Myoglobinuria : Some patients; With intense exercise Strength: Normal Clinical course: Benign Treatment: Dantrolene may reduce[neuromuscular.wustl.edu] (ii) Hypoglycemia accompanied by nausea, vomiting, and pro-fused sweating. This may be due to excessive insulin secretion. (iii) Albuminuria, aminoaciduria.[biologydiscussion.com] Mental retardation, ectopia lentis, sparse blond hair, genu valgum, failure to thrive, thromboembolic episodes, fatty changes of liver.[kumc.edu]

  • Glycogen Storage Disease due to GLUT2 Deficiency

    Related to Increased sarcoplasmic Ca Myalgia Myoglobinuria : Some patients; With intense exercise Strength: Normal Clinical course: Benign Treatment: Dantrolene may reduce[neuromuscular.wustl.edu] Genu valgum, st. Helena familial[?] Genu varum[?] Genuphobia[?] Geographic tongue[?] German syndrome[?] Germinal cell aplasia[?] Gerodermia osteodysplastica[?][encyclopedia.kids.net.au] […] similar to McArdle's Onset: 2nd to 4th decade Exercise intolerance Muscle cramps & Myoglobinuria after vigorous exercise Cramps relieved by rest Pain may be associated with nausea[neuromuscular.wustl.edu]

  • Congenital Absence of Ductus Arteriosus

    , some of these anomalies may lead to various clinical symptoms such as recurrent abdominal pain, nausea and vomiting.[synapse.koreamed.org] Clinical features: • Abdominal pain and swelling, nausea or vomiting. • Note: symptoms absent without pancreatitis Exams and Tests: • Abdominal ultrasound • Abdominal CT scan[slideshare.net] : valgum varum Rudimentary patella Excl.: congenital: dislocation of knee (Q68.2) genu recurvatum (Q68.2) nail patella syndrome (Q87.2) Q74.2 Other congenital malformations[embryology.med.unsw.edu.au]

  • Glycogen Storage Disease due to Phosphoglycerate Mutase Deficiency

    Related to Increased sarcoplasmic Ca Myalgia Myoglobinuria : Some patients; With intense exercise Strength: Normal Clinical course: Benign Treatment: Dantrolene may reduce[neuromuscular.wustl.edu] Wide mouth Irritability Carious teeth Thick vermilion border Sleep disturbance Hypodontia Dysmetria Everted lower lip vermilion Cholestasis Hepatic fibrosis Malabsorption Nausea[mendelian.co] […] be otherwise asymptomatic Cramps Exercise related Electrically silent contractures ?[neuromuscular.wustl.edu]

  • Glycogen Storage Disease

    Related to Increased sarcoplasmic Ca Myalgia Myoglobinuria : Some patients; With intense exercise Strength: Normal Clinical course: Benign Treatment: Dantrolene may reduce[neuromuscular.wustl.edu] Moreover, he complained of chest pain after physical exercise and recurrent nausea.[ojrd.biomedcentral.com] Intervention with custom-molded foot orthoses may improve distal alignment at feet and ankles and secondarily decrease genu valgum, leading to improved weight-bearing alignment[nature.com]

  • Glycogen Storage Disease Type 2

    Related to Increased sarcoplasmic Ca Myalgia Myoglobinuria : Some patients; With intense exercise Strength: Normal Clinical course: Benign Treatment: Dantrolene may reduce[neuromuscular.wustl.edu] Intervention with custom-molded foot orthoses may improve distal alignment at feet and ankles and secondarily decrease genu valgum, leading to improved weight-bearing alignment[nature.com] Adverse effects of laronidase infusion were usually infusion reactions (flushing, fever, and headache) or anaphylactoid reactions (urticaria, rash, nausea, abdominal pain,[dx.doi.org]

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