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258 Possible Causes for Gilbert's Disease, Gynecomastia, Hyperglycemia

  • Hemochromatosis

    Gilbert's syndrome and hereditary hemochromatosis predominantly affect Caucasians with a low incidence in Asians.[ncbi.nlm.nih.gov] Men: Impotence, loss of libido, gynecomastia, testicular atrophy. Women: Amenorrhea and loss of libido.[pathwaymedicine.org] Hemochromatosis is sometimes referred to as bronze diabetes because it can lead to darkening of the skin and hyperglycemia.[diabetes.co.uk]

  • Hyperthyroidism

    Arthritis Rheum. 2007; 56 2715-2718 24 El Fassi D, Banga JP, Gilbert JA. et al.[oadoi.org] […] palpitations and abnormal heart rhythms (the notable ones being atrial fibrillation), shortness of breath (dyspnea), loss of libido, amenorrhea, nausea, vomiting, diarrhea, gynecomastia[en.wikipedia.org] BACKGROUND: Incretin hormones (glucagon-like peptide-1 [GLP-1] and gastric inhibitory polypeptide [GIP]) may play a role in the development of glucose intolerance and hyperglycemia[ncbi.nlm.nih.gov]

  • Paraneoplastic Syndrome

    Joly P, Thomine E, Gilbert D, et al. Overlapping distribution of autoantibody specificities in paraneoplastic pemphigus and pemphigus vulgaris.[doi.org] World J Urol 17:22 PubMed CrossRef Google Scholar Haas GP, Pittaluga S, Gomella L et al (1989) Clinically occult Leydig cell tumor presenting with gynecomastia.[link.springer.com] Refractory hyperglycemia may be due to glucagon -producing pancreatic tumors.[merckmanuals.com]

  • Graves Disease

    A 40-year-old man with reactive arthritis, Graves' disease, type 2 diabetes mellitus, mitral valve prolapse, and Gilbert's disease presented with a one month history of jaundice[casesjournal.biomedcentral.com] Lack of sleep Lack of concentration and inability to focus Women may have less menstrual bleeding or may have no periods at all Men may suffer from erectile dysfunction, gynecomastia[news-medical.net] […] of the skin Easy fatiguability Heat sensitivity Increased sweating Inability to sleep Irritability Irregular menstruation – less frequent and less in amount of blood flow Gynecomastia[ihealthblogger.com]

  • Obesity

    ’s syndrome as the cause of biliary calculosis: Case report, Srpski arhiv za celokupno lekarstvo, 139, 5-6, (386), (2011).[doi.org] Drosophila melanogaster has served as an excellent model for many diseases, including obesity, diabetes, and hyperglycemia-associated disorders, such as cardiomyopathy or[ncbi.nlm.nih.gov] In contrast, diabetic coma due to hyperglycemia accounted for only 4.1% of deaths.[doi.org]

  • Liver Cirrhosis

    Isolated elevation of unconjugated bilirubin level Consider Gilbert syndrome or hemolysis.[aafp.org] Cirrhosis signs, include jaundice, gynecomastia (up to one third of men), loss of axillary and pubic hair, ascites, and splenomegaly (due to portal hypertension), finger clubbing[symptoma.com] Hyperglycemia decreases mitochondrial function: The regulatory role of mitochondrial biogenesis.[ncbi.nlm.nih.gov]

  • Alcoholic Liver Disease

    Wilson's disease may lead to cirrhosis and liver failure. Gilbert's disease. In Gilbert's disease, there is an abnormality in bilirubin metabolism in the liver.[medicinenet.com] […] gain malnutrition and wasting anorexia fatigue confusion pruritus fever nausea and vomiting finger clubbing Dupuytren contracture leg swelling parotid gland enlargement gynecomastia[online.epocrates.com] The side effects of glucocorticosteroids must be also taken into consideration, as some patients on glucocorticosteroids experience adverse effects, mainly in the form hyperglycemia[dx.doi.org]

  • Liver Failure

    […] of the liver Fatty liver disease Galactosemia Gallstones Gilbert's syndrome Hemochromatosis Liver cancer Liver disease in pregnancy Neonatal hepatitis Primary biliary cirrhosis[livescience.com] […] a star of David) Drowsiness and confusion Parotid gland enlargement Spider angiomas Icterus Bilateral parotid swelling ( Credit ) Diminished axillary hair Spider angioma Gynecomastia[stanfordmedicine25.stanford.edu] In patients with hepatic encephalopathy who require high-carbohydrate diets, resulting in postprandial hyperglycemia, rapid-acting insulin analogs such as insulin lispro,[care.diabetesjournals.org]

  • McCune-Albright Syndrome

    Beckwith-Wiedemann Syndrome: Symptoms, Causes, Diagnosis Article The Scoop on Goodpasture Syndrome, a Disease of the Lungs and Kidneys Article Gilbert Syndrome: Symptoms,[rarediseases.about.com] […] growth hormone has been seen in a few patients Most develop course facies, enlarged hands/feet, and arthritis characteristic of acromegaly Associated with gigantism and gynecomastia[en.wikibooks.org] The triad of failure to thrive, hypertension and hyperglycemia is the result of adrenal gland hyperplasia leading to high levels of serum cortisol.[jmedicalcasereports.com]

  • Gigantism

    Pegvisomant-induced liver injury is related to the UGT1A1*28 polymorphism of Gilbert's syndrome. J Clin Endocrinol Metab 2010; 95(5):2147-2154. 144.[ncbi.nlm.nih.gov] Gynecomastia Small, firm testes, azoospermia. Chromatin (Barr) body usually present. (Some may be chromatin negative).[medcaretips.com] Usually hyperglycemia (overactivity of the insulin-producing cells of the pancreas) is present.[infoplease.com]

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