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1,531 Possible Causes for Gliosis

  • Creutzfeldt Jakob Disease

    Extensive spongiform changes were observed in the cerebral neocortex, striatum, thalamus and cerebellar cortex, but gliosis was mild or absent.[ncbi.nlm.nih.gov] This spongiform change begins several months before clinical onset, and is followed by gliosis. Subsequently, neuropil rarefaction appears, followed by neuron loss.[ncbi.nlm.nih.gov] Although approximately 20% of the patients did not have MR imaging abnormalities, MR imaging did show signal intensity alterations due to gliosis and spongiform changes early[ncbi.nlm.nih.gov]

  • Classic Progressive Supranuclear Palsy Syndrome

    In addition, severe fibrillary gliosis was noted in the precentral gyrus and corticospinal tract, being consistent with upper motor neuron syndrome observed in this case.[okayama.pure.elsevier.com] Neuropathologically, all forms are characterized by neuronal loss, gliosis with astrocytic plaques and accumulation of tau-immunoreactive neurofibrillary tangles in specific[orpha.net]

  • Binswanger Disease

    […] vascular dementia with hydrocephalus, was characterized pathologically in five patients by severe thickening of small vessels and by diffuse regions of white matter loss with gliosis[ncbi.nlm.nih.gov] […] with calcification and retraction 526 Lowgrade astrocytoma no progression in two years 528 Periinsular gliosis 529 Refractory partial epilepsy gliosis of the temporal lobe[books.google.de] The pathogenesis of subcortical arteriosclerotic encephalopathy is unknown; possible mechanisms include diffuse ischemia and fluid transudation with subsequent gliosis related[ncbi.nlm.nih.gov]

  • Medial Sclerosis

    […] marked by nystagmus, ataxia, tremor, parkinsonian facies, dysarthria, and mental deterioration. hippocampal sclerosis loss of neurons in the region of the hippocampus, with gliosis[medical-dictionary.thefreedictionary.com] The most common pathology in surgically resected specimens is that of mesial temporal sclerosis (gliosis and scarring in the mesial temporal lobe).[casemed.case.edu] Microscopic features are decrease in hippocampal neurons and gliosis.[neuroradiologycases.com]

  • Hallervorden-Spatz Syndrome

    The main ocular findings included degeneration of photoreceptors, marked thinning of the outer nuclear and outer plexiform layers, retinal gliosis, narrowing and obliteration[ncbi.nlm.nih.gov] The classic histological hallmarks of HSS are axonal spheroids and excessive iron-containing granules accompanied by neuronal loss and gliosis in the globus pallidus and substantia[ncbi.nlm.nih.gov] The striatum showed a moderate degree of neuronal loss and gliosis affecting chiefly the large neurons.[jnnp.bmj.com]

  • Progressive Supranuclear Palsy

    Microscopic observations showed extensive superficial spongiosis and severe neuronal loss with gliosis in the second and third cortical layers in the frontal, temporal and[ncbi.nlm.nih.gov] In addition, moderate to severe loss of neurons was found with gliosis and a lot of Gallyas/tau‐positive globus neurofibrillary tangles in the caudate nucleus, globus pallidus[doi.org] Neuropathological features included neuronal loss and gliosis in the substantia nigra, locus ceruleus, dorsal motor nucleus of the vagus, thoracic intermediolateral nucleus[ncbi.nlm.nih.gov]

  • Autosomal Recessive Primary Microcephaly Type 10

    Diseases related with Microcephaly and Gliosis In the following list you will find some of the most common rare diseases related to Microcephaly and Gliosis that can help[mendelian.co] Gliosis MedGen UID: 4899 • Concept ID: C0017639 • Pathologic Function Gliosis is the focal proliferation of glial cells in the central nervous system.[ncbi.nlm.nih.gov] Not very common - Between 30% and 50% cases Abnormal cerebellum morphology Commonly - More than 50% cases Delayed myelination Not very common - Between 30% and 50% cases Gliosis[mendelian.co]

  • Rasmussen Syndrome

    Histopathologic examination of biopsy material reveals a characteristic triad of findings: perivascular lymphocytic cuffing of round cells, gliosis and microglial nodules.[asnr.org] Atrophy is progressive, may be associated with cortical gliosis. Rasmussen Encephalitis, a chronic progressive encephalitis results in severe, intractable epilepsy.[neuroradiologycases.com]

  • Leigh's Disease

    In addition, there was severe leukoencephalopathy of the cerebral hemispheres with sudanophilic tissue degregation, advanced axonal loss and reactive astrocytic gliosis.[ncbi.nlm.nih.gov] It was characterized by necrosis, gliosis, and status spongiosus of the neuropil with relatively preserved neurons, and hyperplasia of small blood vessels as well as endothelium[ncbi.nlm.nih.gov] At autopsy, extensive symmetric lesions were found in the brain including proliferation of capillaries and gliosis in the brain stem and diffuse demyelination in the white[ncbi.nlm.nih.gov]

  • Retinal Angioma

    Massive gliosis in VHL disease is a true reactive retinal gliosis.[ncbi.nlm.nih.gov] Inferiorly from 5:00 to clockwise 6:30 in the mid-periphery, there are two almost contiguous clusters of red dilated saccules in the retina, with central gray-white surface gliosis[webeye.ophth.uiowa.edu] Apoptosis detected by TUNEL revealed lack of DNA fragmentation in the angioma; in contrast, many positive signals were found in the massive gliosis.[ncbi.nlm.nih.gov]

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