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147 Possible Causes for Gliosis in the Basal Ganglia

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  • Glutaric Aciduria

    Format Definition An autosomal recessive metabolic disorder characterized by progressive dystonia and athetosis due to gliosis and neuronal loss in the basal ganglia.[]

  • Relapsing Polychondritis

    A histological examination revealed perivascular lymphocytic cuffing and infiltration in the small vessels, as well as loss of nerve cells and gliosis in the basal ganglia[]

  • Infantile Neuroaxonal Dystrophy

    SSB were observed in the thalamus, basal ganglia and the cerebral cortex.[] LSB were prominent in the posterior column, gracile nucleus, cuneate nucleus, and the tegmentum of the midbrain and the pons associated with neuronal loss and gliosis.[]

  • MELAS Syndrome

    Prominent bilateral basal ganglia calcifications and vascular sclerosis were present, and a small remote left temporal lobe infarct was seen.[] The brain at autopsy showed mild cerebral atrophy and diffuse cortical gliosis.[]

  • Biotin-Responsive Basal Ganglia Disease

    D-F, Repwith residual atrophy and gliosis in the basal ganglia (white arrowJ Pediatr 2013;162:1291-2.0022-3476/ - see front matter.[] Repeat MRI showed resolution of vasogenic edema but residual atrophy and gliosis in the basal ganglia.[] Repeated brain MRI showed resolution ofthe vasogenic edema with residual atrophy and gliosis inthe basal ganglia (Figure).The physical exam finding of acute to subacute, bilateralexternal[]

  • Spinocerebellar Ataxia Type 1

    Multiple system atrophy is a sporadic progressive neurological disorder with degeneration and gliosis in the basal ganglia, cerebellum, brainstem, and spinal autonomic nuclei[] Spinocerebellar ataxia type 1 (SCA1) is a dominantly inherited progressive neurological disorder characterized by neuronal degeneration and reactive gliosis in the cerebellum[]

  • Dihydropyrimidine Dehydrogenase Deficiency

    Cranial magnetic resonance imaging at 14 months indicated severe hypomyelination with gliosis. Her basal ganglia were also involved.[]

  • Gangliosidosis

    Cranial magnetic resonance imaging at 14 months indicated severe hypomyelination with gliosis. Her basal ganglia were also involved.[]

  • Asphyxia

    The thalamus and basal ganglia have a light color and firm consistency due to a gliosis and myelin abnormalities.[] Thalamic and basal ganglia damage causes, over time, loss of neurons, mineralization of damaged neurons, and gliosis.[] Irregular patches of dense myelin mixed with gliotic zones give the thalamus and basal ganglia a marbled appearance to the naked eye, a condition called status marmoratus[]

  • AIDS Dementia Complex

    N-acetylaspartate, a marker of mature neurons, choline and myoinositol, both markers of gliosis, and creatine, a reference marker, were measured in the basal ganglia, frontal[] ganglia and white matter, where gliosis and inflammatory changes are noted, the level of choline-containing metabolites, which is a marker of glial metabolism, is increased[] This study provides convincing evidence that neuropsychological impairment is associated with reduced markers of mature neurons and increased markers of gliosis in the basal[]

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