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413 Possible Causes for Gliosis of the White Matter

  • Insomnia

    MRI indicated a diffuse white matter abnormality and microbleeding on the susceptibility-weighted imaging.[] On biopsy, the brain tissue sections showed spongiform changes with gliosis, neuronal degeneration, and prion protein deposition in a portion of the neurons.[]

  • Cerebral Angiitis

    Brain biopsy showed necrosis and gliosis of the white matter, but no vasculitic changes. Autopsy revealed numerous necroses of the cerebral cortex and white matter.[]

  • Binswanger Disease

    matter loss with gliosis.[] Pathological features: lacunes, subcortical white matter demyelination, neuronal loss, gliosis, ventricular dilatation and atheromatosis of the larger cerebral vessels.[] […] encephalopathy, a chronic vascular dementia with hydrocephalus, was characterized pathologically in five patients by severe thickening of small vessels and by diffuse regions of white[]

  • Hypomyelinating Leukodystrophy Type 5

    Deep cerebellar white matter hypomyelination was found in 6 patients. Older patients had evidence of white matter bulk loss and gliosis.[] , eventually leading to white matter gliosis and bulk loss.[] The periventricular white matter is more hyperintense than the subcortical white matter, suggesting superimposed gliosis. (more...) Figure 5.[]

  • Necrotizing Alveolitis

    Neuropathological examination revealed diffuse oedema, perivascular cuffing and gliosis in the white matter.[]

  • Periventricular Leukomalacia

    Abstract The most common form of brain injury in preterm infants is focal necrosis and gliosis of the periventricular white matter, generally referred to as periventricular[] […] cerebral white matter.[] Periventricular leukomalacia (PVL), the key feature of encephalopathy of prematurity, is characterized by periventricular necrotic foci and diffuse gliosis in the surrounding[]

  • Posterior Cerebral Artery Occlusion with Infarction

    There may discoloration, with the appearance being "muddy-looking" due to changes in the line between gray and white matter.[] As nerve cells disintegrate, they are replaced by the neuroglia (gliosis). At the onset of the cerebral ischemic event, there is a gradation in brain perfusion.[]

  • Presenile Dementia with Bone Cysts

    From Epidemiology 160 cases, mainly in Finland & Japan onset third decade Pathology basal ganglia calcification gliosis white matter demyelination senile plaques neurofibrillary[] The demyelination typically involves the entire white matter.[] Brain histopathology is characterized by frontal loss of myelin and nerve fibres, with axonal spheroids, lipid-loaded macrophages and extensive astrocytic reaction and gliosis[]

  • Late-onset Depression

    Neuropathological evaluation included bilateral semi-quantitative assessment of lacunes, deep white matter and periventricular demyelination, cortical microinfarcts and both[] […] focal and diffuse gliosis.[]

  • Severe Neonatal-Onset Encephalopathy with Microcephaly

    There was diffuse gliosis of the white matter in all areas of the brain.[] There is a severe loss of neurons in pontine and olivary nuclei in addition to the hypoplasia of the cerebellum and a diffuse gliosis in white matter of both the cerebellum[] Microscopic examination showed multiple cortical necroses and subcortical and axial white matter involvement with demyelination, dense fibrillary gliosis, and lipid-laden[]

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