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30 Possible Causes for Globulins Increased, Pain, Virus Associated Hemophagocytic Syndrome

  • Sickle Cell Disease

    (which contains 2 gamma globulin chains instead of 2 beta globulin ones, the latter being genetically malformatted by the disease) and thus decreases the number of attacks[en.wikipedia.org] Mean pain intensity on crisis days, noncrisis pain days, and total pain days increased as the percentage of pain days increased (P 0.001).[ncbi.nlm.nih.gov] One study showed that cognitive behaviour therapy significantly reduced the affective component of pain (feelings about pain), mean difference -0.99 (95% confidence interval[ncbi.nlm.nih.gov]

  • Infectious Mononucleosis

    , gamma globulin increased less frequently, and beta globulin, which was normal in practically all the cases of infectious mononucleosis, was increased in a considerable number[link.springer.com] Severe chronic active Epstein-Barr virus infection accompanied by virus-associated hemophagocytic syndrome, cerebellar ataxia and encephalitis.[emedicine.medscape.com] The evaluation of a febrile patient with acute abdominal pain represents a frequent yet possibly challenging situation in the emergency department (ED).[ncbi.nlm.nih.gov]

  • Chronic Active Hepatitis

    Severe chronic active hepatitis, defined as the presence of a fivefold increase in serum aminotransferases and a twofold rise in gamma globulin for at least 10 weeks, is considered[ncbi.nlm.nih.gov] Bone marrow biopsy showed hypocellularity, histiocytic hyperplasia, and hemophagocytosis consistent with a virus-associated hemophagocytic syndrome (VAHS).[ncbi.nlm.nih.gov] Nursing Nutrition Nutrition, Obesity, Exercise Obesity Obstetrics and Gynecology Occupational Health Oncology Ophthalmic Images Ophthalmology Orthopedics Otolaryngology Pain[jamanetwork.com]

  • Autoimmune Hepatitis

    More than 80% of affected individuals have increased gamma globulin in the blood.[hepatitiscentral.com] Virus-, drug- and lymphoma-associated hemophagocytic syndrome (HPS) was ruled out. Therefore, the patient was diagnosed with autoimmune-associated HPS (AAHS).[ncbi.nlm.nih.gov] We report a case with torpid evolution, presented with multiple and deep ulcers in a young patient with autoimmune hepatitis, causing pain and significant disability.[ncbi.nlm.nih.gov]

  • Hodgkin Lymphoma

    Hodgkin lymphoma-associated hemophagocytic syndrome: a disorder strongly correlated with Epstein-Barr virus. Clin Infect Dis. 2008 Aug 15. 47(4):531-4. [Medline].[emedicine.medscape.com] We reported a 14-year-old boy initially evaluated with pain localized at the left ilium.[ncbi.nlm.nih.gov] Here we present a 52-year-old male complaining of epigastric pain and fever diagnosed as stomach adenocarcinoma and Hodgkin's lymphoma.[ncbi.nlm.nih.gov]

  • Hepatitis A

    , which can help increase protection to HAV.[liverfoundation.org] hemophagocytic syndrome [3].[ncbi.nlm.nih.gov] The patient was initially discharged with improved pain, but later presented to a primary care clinic with weight loss and continued pain.[ncbi.nlm.nih.gov]

  • Lymphoma

    The erythrocyte sedimentation rate is a sign of activity of the disease and is caused by the increase of the a2-globulins and of the gamma globulins.[lecturio.com] Hodgkin lymphoma-associated hemophagocytic syndrome: a disorder strongly correlated with Epstein-Barr virus. Clin Infect Dis. 2008 Aug 15. 47(4):531-4. [Medline].[emedicine.medscape.com] […] many symptoms, such as Swollen, painless lymph nodes in the neck, armpits or groin Unexplained weight loss Fever Soaking night sweats Coughing, trouble breathing or chest pain[nlm.nih.gov]

  • Erythema Infectiosum

    IV immune globulin has been used to curtail viremia and increase erythropoiesis in immunocompromised patients with pure RBC aplasia.[merckmanuals.com] Virus-associated hemophagocytic syndrome.[cmr.asm.org] However, in some cases pain in joints may also occur.[symptoma.com]

  • Chronic Active Hepatitis B

    In all patients AST and ALT values returned to normal and there was a fall in serum delta GT and improvement of prothrombin time. an increase of globulins was noted.[ncbi.nlm.nih.gov] Bone marrow biopsy showed hypocellularity, histiocytic hyperplasia, and hemophagocytosis consistent with a virus-associated hemophagocytic syndrome (VAHS).[ncbi.nlm.nih.gov] Despite treatment with medication for the pain at another hospital, the sensory symptoms progressed.[synapse.koreamed.org]

  • Precursor-Cell Lymphoblastic Leukemia

    Late-onset fatal Epstein-Barr virusassociated hemophagocytic syndrome following cord blood cell transplantation for adult acute lymphoblastic leukemia .[ajcp.oxfordjournals.org] We aimed to describe small-fiber toxicity and pain sensitization in this group.[ncbi.nlm.nih.gov] CASE REPORT A 20-year-old man began to experience cough, chest pain, and mild exertional dyspnea.[ncbi.nlm.nih.gov]

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