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1,343 Possible Causes for Globulins Increased, Scleral Icterus, Virus Associated Hemophagocytic Syndrome

  • Sickle Cell Disease

    Enlarged liver, with jaundice and yellowing of the whites of the eyes (scleral icterus) Marked enlargement of bone marrow and possible significant deformities of some bones[labtestsonline.org]

  • Chronic Active Hepatitis B

    In all patients AST and ALT values returned to normal and there was a fall in serum delta GT and improvement of prothrombin time. an increase of globulins was noted.[ncbi.nlm.nih.gov] Bone marrow biopsy showed hypocellularity, histiocytic hyperplasia, and hemophagocytosis consistent with a virus-associated hemophagocytic syndrome (VAHS).[ncbi.nlm.nih.gov] Physical examination is remarkable for right upper quadrant tenderness, generalized jaundice, and scleral icterus.[medbullets.com]

  • Hepatitis A

    , which can help increase protection to HAV.[liverfoundation.org] hemophagocytic syndrome [3].[ncbi.nlm.nih.gov] We report a 3-year-old boy presenting with 3 days of fever, vomiting, abdominal distention and scleral icterus.[ncbi.nlm.nih.gov]

  • Autoimmune Hepatitis

    More than 80% of affected individuals have increased gamma globulin in the blood.[hepatitiscentral.com] Virus-, drug- and lymphoma-associated hemophagocytic syndrome (HPS) was ruled out. Therefore, the patient was diagnosed with autoimmune-associated HPS (AAHS).[ncbi.nlm.nih.gov] Relapse is characterized by an increase in the serum aminotransferase level to more than 3-fold the upper limit of normal and/or increase in the serum gamma-globulin level[gastrotraining.com]

  • Portal Cirrhosis

    .  Prothrombin time - increases since the liver synthesizes clotting factors.  Globulins - increased due to shunting of bacterial antigens away from the liver to lymphoid[slideshare.net] icterus Vascular spiders (spider telangiectasias, spider angiomata) Splenomegaly Testicular atrophy TABLE 2 Common Physical Examination Findings in Patients with Cirrhosis[aafp.org] icterus Yellow discoloration of skin, cornea, and mucous membranes Increasing serum bilirubin due to compromised hepatocyte excretory function Spider angiomata Central arteriole[pathophys.org]

    Missing: Virus Associated Hemophagocytic Syndrome
  • Macronodular Cirrhosis

    Protein immunoelectrophoresis may reveal decreased a-1 globulins ( a-1 antitrypsin deficiency ), increased IgA (alcoholic cirrhosis), increased IgM (primary biliary cirrhosis[encyclopedia.lubopitko-bg.com] Globulinsincreased due to shunting of bacterial antigens away from the liver to lymphoid tissue.[en.wikipedia.org] Protein metabolism tests show decreased total protein, decreased albumin, and increased globulin.[medical-dictionary.thefreedictionary.com]

    Missing: Virus Associated Hemophagocytic Syndrome
  • Ascending Cholangitis

    Initial Presentation: Jaundice Abdominal pain Fever Vital Signs: Fever can be present given this is an infectious process Dermatological Exam: Scleral icterus Jaundice Abdominal[stepwards.com] She has scleral icterus and jaundice (worsened per family). The patient grimaces on palpation of the right upper quadrant.[emdocs.net]

    Missing: Virus Associated Hemophagocytic Syndrome
  • Cryptogenic Cirrhosis

    Serum globulin increases in cirrhosis and in most liver disorders with an inflammatory component.[merckmanuals.com]

    Missing: Virus Associated Hemophagocytic Syndrome
  • Viral Hepatitis

    Physical exam Assessment of the patient may yield remarkable findings such as jaundice, scleral icterus, and an enlarged and tender liver.[symptoma.com] Icteric Phase During this phase clinical signs of jaundice and scleral icterus will appear and some right upper quadrant tenderness may develop due to enlargement of the liver[pathwaymedicine.org]

    Missing: Virus Associated Hemophagocytic Syndrome
  • Alcoholic Hepatitis

    […] serum globulin levels Metabolic Elevated blood ammonia level Hyperglycemia Respiratory alkalosis Hypomagnesemia Hypophosphatemia Hyponatremia Hypokalemia Back to Top Treatment[clevelandclinicmeded.com] Physical Exam: VS: T 98.9 HR 104 RR 19 BP 117/67 O2 99% RA Gen: Well-appearing obese female in no acute distress HEENT: PERRL, marked scleral icterus, sublingual icterus,[ddxof.com] icterus, skin and sublingual jaundice).[clinicaladvisor.com]

    Missing: Virus Associated Hemophagocytic Syndrome

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