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56 Possible Causes for Glomerular Cellularity Increased

  • Hyperkalemia

    This can be further intensified by active cellular breakdown which causes increase in serum potassium levels.[] This is especially pronounced in acute kidney injury where the glomerular filtration rate and tubular flow are markedly decreased, characterised by reduced urine output.[]

  • Preeclampsia

    Glomerular cellularity is not significantly increased.[] Glomerular endotheliosis: (A) Glomerulus showing occlusion of capillary lumens by swelling of endocapillary cells. There is no appreciable increase in cellularity.[] Glomerular volume is increased and correlates with the severity of the disease. 5 The degree of endotheliosis can vary between glomeruli, although most show at least some[]

  • Diabetic Nephropathy

    These mechanisms bring about various downstream changes at the cellular level that eventually lead to disruption of the glomerular filtration barrier, visualized on histologocal[] […] hyperfiltration, protein kinase C pathway activation and increase in advanced glycation end-products (AGEs).[] […] pathogenesis of DN, which include polyol pathway activation, effect of high glucose, activation of renin-angiotensin system, formation of reactive oxygen species (ROS), glomerular[]

  • Haddad Syndrome

    Cellular casts usually indicate a more severe form of glomerular injury [ 3 ]. Glomerular hematuria is usually accompanied by increased albuminuria.[] In patients with glomerular hematuria, acanthocytes are far more common than cellular casts.[] Increased numbers of small red cells is also characteristic of glomerular hematuria [ 2 ]. • The presence of casts that contain red cells or a mixture of red cells and white[]

  • Glomerulonephritis

    Structurally, cellular proliferation leads to an increase in the number of cells in the glomerular tuft because of the proliferation of endothelial, mesangial, [4] and epithelial[]

  • ACE Inhibitor-Induced Angioedema

    Figure 1. a) A glomerulus with severe mesangial matrix expansion by PAS positive material associated with mild to moderate increase in mesangial and endocapillary cellularity[] , (PAS stain, original magnification 400X). b) Intense pseudolinear staining along glomerular basement membranes, tubular basement membranes, and Bowman’s capsule and smudgy[]

  • Nonallergic Interstitial Nephritis

    Other changes include: increase of the matrix and/or mesangial cellularity, endocapillary proliferation, thickening of capillary walls, glomerular tuft necrosis, extracapillary[] [Top] Histopathology Glomerular changes are highly variable. The commonest alteration is the presence of mesangial and/or capillary immune deposits.[]

  • Membranoproliferative Glomerulonephritis

    The pathologic findings shown here include increased glomerular overall cellularity, mainly increased mesangial cellularity.[] This histological multiform with MCD is valuable for increasing our understanding of the mechanism for onset of immune-complex glomerular deposition and cellular proliferation[]

  • Chronic Glomerulonephritis

    The pathologic findings shown here include increased glomerular overall cellularity, mainly increased mesangial cellularity.[] The increase in cellularity and mesangial matrix produces accentuation of the lobular aspect of the glomerular tuft (lobular GN).[] With disease progression the cellularity gradually diminishes and the acellular matrix increases, the tuft appear “solidified” and nodules with acellular center can be seen[]

  • Nephrotic Syndrome

    The pathophysiology revolves round the onset of lesions that may increase the cellularity of glomerular membrane (along with leukocytic infiltration).[]

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