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14 Possible Causes for Glossitis, Vacuolation of Granular Layer

  • Glucagonoma

    A skin biopsy performed on a peritibial lesion showed a spongiotic epidermis with vacuolization of the granular layer and presence of necrotic keratinocytes in the horny layer[] This report describes a classic presentation consisting of dermatitis, glossitis, stomatitis, angular cheilitis, anemia, and weight loss that was associated with the finding[] Glucagonoma syndrome encompasses necrolytic migratory erythema (NME), hyperglucagonemia, diabetes mellitus, anemia, weight loss, glossitis, angular cheilitis, steatorrhea,[]

  • Hereditary Koilonychia

    Cellular breakdown in the spinous and granular cell layers occurs rarely and can lead to blister formation.[] […] hormone Muscle conditions Universal lupus Hemochromatosis Patella Syndrome Raynaud’s Syndrome Erythematosus Poor health Iron deficiency anemia Using too much soap or oil Glossitis[] Excessive usage of oils and soaps Thyroid dysfunction Musculoskeletal condition Renal disease Contact dermatitis Raynaud’s disease Systemic lupus erythematosus Cheilosis Glossitis[]

  • Zosteriform Lentiginosis

    […] keratinocytes and extracellular granular material in the basal layer of the normal skin adjacent to areas of vitiligo. 254 If serial sections are examined, a lymphocyte will[] […] atrophicans K glossitis mediana rhomboidalis K glossitis nno K glossitis, ulcererend K glossodynie (burning mouth syndroom) K gonorrhoea chronica, urogenitaal A gonorrhoea[] […] dermoepidermal interface was observed in 89% of these cases. 253 Focal spongiosis is sometimes present in the marginal areas of vitiligo. 250 Ultrathin sections will often show vacuolated[]

  • Lytic Bone Lesion

    Cellular breakdown in the spinous and granular cell layers occurs rarely and can lead to blister formation.[] Transverse overcurvature can be observed in patients with onychomatricoma, subungual myxoid cysts, median rhomboid glossitis, and systemic sclerosis [ 5 ].[] Perinuclear vacuolization and large keratohyalin granules are seen.[]

  • Necrobiotic Xanthogranuloma

    (D) Large vacuolated cells with grayish cytoplasm and vesicular nuclei in the upper spinal and granular layers (original magnification x100).[] *glossitis catarrhalis[L] 【カフェオーレ斑】*cafe-au-lait spot 【カポジ肉腫】*Kaposi's sarcoma 【カリウム血症】*kalemia 【カリウム欠乏症】*kaliopenia 【カリニ肺炎】*pneumocystis carinii pneumonia 【カルチノイド】*carcinoid[] […] nuclei in the upper spinal and granular layers; changes characteristic of EDV ( Figure 2D ).[]

  • Lamellar Ichthyosis

    In the prominent granular layer some of the keratinocytes exhibited cytoplasmic edema and coarse inclusions of keratohyalin.[] Pellagra Metabolic - Tryptophan - Niacin Pathway Nutritional Deficiencies/ Niacin Deficiency/ Pellagra Phrynoderma Scurvy Vitamin B12 Deficiency Biermer's Anemia Glossitis[] […] benign familial neonatal seizures benign familial pemphigus benign fibrous histiocytoma benign focal amyotrophy benign Mediterranean macrothrombocytopenia benign migratory glossitis[]

  • Condyloma Latum

    High-magnification view of the granular layer demonstrates coarse hyaline granules with scattered koilocytic changes (hyperchromatic nuceli with vacuolization).[] Other intra-oral findings may include atrophic glossitis, palatal cleft, and perioral rhagades (fissures) (15,19).[]

  • Carcinoma in Situ of Sphenoid Sinus

    […] cell layer, and often contain numerous vacuolated cells suggestive of koilocytes.[] […] facial paralysis顔面神経麻痺 fistula瘻孔 fistula symptom瘻孔症状 floor of mouth口腔底 foreign body異物 frontal sinus前頭洞 g gaze nystagmus注視眼振 geographic tongue地図状舌 gingiva歯肉 gingivitis歯肉炎 glossitis[] […] reminiscent of a verruca vulgaris; that is, it will show focal papillary squamous epithelial hyperplasia with marked keratosis and/or parakeratosis, with or without a prominent granular[]

  • Human Papillomavirus

    There is diffuse vacuolation and increase in cell size with centralization of nuclei that become strongly basophilic and pyknotic in the spinous and granular layers.[] The eruption is accompanied by adult-onset diabetes mellitus, weight loss, and glossitis.[] […] nuclei in the horny layer and amorphous eosinophilic cytoplasmic inclusions in the cells with peripherally located nuclei in the granular and prickle cell layers.[]

  • Verrucous Carcinoma

    The granular layer was prominent and many cells were vacuolated, resembling the koilocytes of viral warts. There was minimal dysplasia.[] Geographic tongue Median rhomboid glossitis Transient lingual papillitis Glossoptosis Hypoglossia Lingual thyroid Macroglossia Microglossia Rhabdomyoma Palate Bednar's aphthae[] Nasolabial cyst Sun poisoning Trumpeter's wart Tongue Ankyloglossia Black hairy tongue Caviar tongue Crenated tongue Cunnilingus tongue Fissured tongue Foliate papillitis Glossitis[]

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