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158 Possible Causes for Glucose Increased, Insulin Increased, Variable Hypoglycemia

  • Diabetes Mellitus

    Associated Complications: CNS : retinopathy, peripheral neuropathies, and autonomic neuropathy (decreased heart rate variability, orthostatic hypotension, gastroparesis,[openanesthesia.org] […] frequency of insulin-dependent diabetes in several countries is best explained today by the decline of infections.[dx.doi.org] As the blood glucose level increases, so also does the glucose content in the aqueous humor.[aao.org]

  • Septicemia

    This conclusion is supported by the wide variability in hypoglycemia rates reported with protocols [ 205, 206, 207, 212, 213 ].[doi.org] Furthermore it was also pointed out that intensive insulin therapy increased the labor requirement of nursing staff in the ICU[ 26 ].[doi.org] This conclusion is supported by the wide variability in hypoglycemia rates reported with protocols [ 205 – 207, 212, 213 ].[ncbi.nlm.nih.gov]

  • Glycogen Storage Disease Type 6

    Individuals with GSD VI typically exhibit hepatomegaly, growth retardation, and variable but mild episodes of fasting hypoglycemia and hyperketosis during early childhood.[emedicine.com] Ingestion of glucose alone, glucose plus prtrteiu Or infusion of arginine monochlorid resulted in significantly less than normal increase in insulin.[diabetes.diabetesjournals.org] Oral galactose and fructose fail to increase glucose levels but plasma lactic acid levels increase.[patient.info]

  • Islet Cell Tumor

    PNETs are functional or non-functional tumors and represent a heterogeneous group of neoplasms with extremely variable clinical behavior.[ec.bioscientifica.com] It is considered to cause hypoglycemia by increasing the insulin-like bioactivity of the circulating insulin-like growth factor (IGF) system, however, the precise mechanism[ncbi.nlm.nih.gov] Glucagon also plays a role in the amount of glucose in the bloodstream, and in this case, it increases the amount of glucose present.[uhhospitals.org]

  • Insulin Resistance

    Armen, Simulation and qualitative analysis of glucose variability, mean glucose, and hypoglycemia after subcutaneous insulin therapy for stress hyperglycemia, Theoretical[doi.org] (Reuters Health) - Insulin resistance may increase the risk for Alzheimer’s disease by depriving the brain of sugar needed for normal cognition, a small study suggests.[reuters.com] This was associated with suppression of endogenous glucose production by 42%, increased glucose utilization by 64%, and increased glucose oxidation by 100%.[doi.org]

  • Diabetes Mellitus Type 2

    The choice of glycemic target also depends on consideration of other variables, such as risk for hypoglycemia, weight gain, and other drug-related adverse effects, as well[doi.org] However, sulfonylurea might increase the secretion of insulin, which might contribute to sympathoexcitation.[austinpublishinggroup.com] glucose concentration and associated glycemia/HbA1c values, with the strength of the correlation increasing for higher glycemia/HbA1c values.[ncbi.nlm.nih.gov]

  • Hypoglycemia

    Glycemic variability portends increased risk for hypoglycemia and should be a focus of further research.[ncbi.nlm.nih.gov] Insulin levels were not different among sessions, whereas glucagon increased with MDG administration ( P 0.001).[ncbi.nlm.nih.gov] Continuous monitoring of glycemia due to the ability to show glycemia variability and unrecognized hypoglycemia as well as predictive options for long-term metabolic control[ncbi.nlm.nih.gov]

  • Diabetic Ketotic Coma

    Glycemic variability: A strong independent predictor of mortality in critically ill patients. Crit Care Med 2008;36:3008-3013. Moore C, Woollard M.[ahcmedia.com] If glucose levels do not decrease by 50-75 mg/dL during the first hour of insulin therapy, the insulin infusion should be increased every hour until a steady decline in glucose[endocrinologyadvisor.com] As the blood glucose levels increase in HHS, the body tries to get rid of the excess glucose by increased urinary volume.[star2.com]

  • Diabetes Mellitus Type 1

    There was no significant between-group difference in the number of severe hypoglycemia events. (p 0.1276).[ncbi.nlm.nih.gov] Postprandial glucose levels increased more markedly in T1DM (to 22.1 1.4 vs. 11.2 0.6mmol/L) while insulin levels increased only in T2DM (from 24.4 4.4 to 68.8 12.3μU/mL).[ncbi.nlm.nih.gov] […] pump If patient is on epinephrine, glucocorticoids, or growth hormone, there may be an increase in blood glucose levels, thus an increased level of insulin may be needed.[physio-pedia.com]

  • Insulinoma

    A somatostatin analog, octreotide (100 to 500 mcg sc bid to tid), is variably effective and should be considered for patients with continuing hypoglycemia refractory to diazoxide[merckmanuals.com] Insulin sensitivity was greatly reduced in patients with insulinoma (38.9% 22.3%), while beta cells function was increased (359.0 171.5%), but to a variable extent (range:[ncbi.nlm.nih.gov] Then, the frequency of blood glucose measurement is increased to every hour until values are 49 mg/dL (2.7 mmol/L).[en.wikipedia.org]

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