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3,588 Possible Causes for Glucose Increased, Mutation in the EIF2AK3 Gene, Onset of Renal Dysfunction in Early Childhood

  • Wolcott-Rallison Syndrome

    Beta cells are needed for the proper release of insulin into the blood stream after an increase in blood glucose.[en.wikipedia.org] Mutations in the EIF2AK3 gene have been identified in patients with Wolcott-Rallison syndrome - a rare autosomal recessive disorder associated with permanent neonatal insulin-dependent[ncbi.nlm.nih.gov] Beta cells are needed for the proper release of insulin into the blood stream after an increase in blood glucose. [4] This kinase is needed for the control of protein levels[wikiwand.com]

  • DEND Syndrome

    Panel A shows the median incremental increase in insulin concentration above baseline in an intravenous glucose-tolerance test (16 patients) and an oral glucose-tolerance[nejm.org] NEUROD1, IER3IP1, NEUROG3, NKX2-2 ), recessively inherited mutations in the EIF2AK3 gene, which cause Wolcott Rallison Syndrome, are the most common cause of PNDM in consanguineous[diapedia.org] NEUROD1, IER3IP1, MNX1, NEUROG3, NKX2-2, RFX6, GLIS3, PTF1A, PDX1 ), recessively inherited mutations in the EIF2AK3 gene, which cause Wolcott-Rallison syndrome, are the most[diapedia.org]

    Missing: Onset of Renal Dysfunction in Early Childhood
  • Metabolic Syndrome

    She also had impaired glucose tolerance and markedly increased basal and post-glucose load plasma insulin levels.[ncbi.nlm.nih.gov] Increased blood clotting.[hopkinsmedicine.org] This means you have type 2 diabetes, impaired fasting glucose, or impaired glucose tolerance. The impaired glucose tolerance test measures the body's response to sugar.[hopkinsmedicine.org]

    Missing: Mutation in the EIF2AK3 Gene Onset of Renal Dysfunction in Early Childhood
  • Third Trimester Pregnancy

    , and this is likely to reflect a pathological process rather than the physiological effect of pregnancy on maternal glucose tolerance.[ncbi.nlm.nih.gov] The outcome of pregnancy was compared among the groups with negative screening, positive screening but normal glucose tolerance, and gestational diabetes which was controlled[ncbi.nlm.nih.gov] RESULTS: Women with gestational diabetes (n 67 or 13.7%) had significantly increased maternal age, pre-pregnancy weight and body mass index, hemoglobin levels at booking and[ncbi.nlm.nih.gov]

    Missing: Mutation in the EIF2AK3 Gene Onset of Renal Dysfunction in Early Childhood
  • Diabetes Mellitus

    As the blood glucose level increases, so also does the glucose content in the aqueous humor.[aao.org] […] urination) Polydipsia (increased thirst) Polyphagia (Increased appetite) Glycosuria (glucose in urine) Weight loss despite polyphagia Hyperglycemia (increased blood glucose[physio-pedia.com] In both cases, the levels of glucose in the blood increase, causing hyperglycemia (high blood sugar).[britannica.com]

    Missing: Mutation in the EIF2AK3 Gene Onset of Renal Dysfunction in Early Childhood
  • Polycystic Ovary Syndrome

    In addition, with FAI increase, glycosylated hemoglobin (HbA1c), plasma glucose concentrations, and serum insulin levels increased, while insulin sensitivity and β -cell function[ncbi.nlm.nih.gov] Because the combined oral contraceptive (COC) use has also been associated with impaired fasting glucose, insulin resistance and increased risk of thromboembolism disease,[ncbi.nlm.nih.gov] Metformin, a biguanide compound, exerts its clinical effect by both reducing hepatic glucose output and by increasing insulin sensitivity.[web.archive.org]

    Missing: Mutation in the EIF2AK3 Gene Onset of Renal Dysfunction in Early Childhood
  • Diabetes Mellitus Type 2

    glucose concentration and associated glycemia/HbA1c values, with the strength of the correlation increasing for higher glycemia/HbA1c values.[ncbi.nlm.nih.gov] Fasting plasma glucose increased by 2.07 0.82 mmol/L in the control group and 1.38 0.81 mmol/L in the diet group. 2‐hour plasma glucose increased by 3.96 0.89 mmol/L in the[doi.org] CONCLUSIONS: Our systematic review reports an overall meaningful salivary glucose concentration increase in type 2 DM and a significant overall relationship between salivary[ncbi.nlm.nih.gov]

    Missing: Mutation in the EIF2AK3 Gene Onset of Renal Dysfunction in Early Childhood
  • Chronic Kidney Insufficiency

    […] amounts of glucose, red blood cells, white blood cells and protein within the urine.[kidneyandhypertensioncare.com] The increase in urine glucose can result in a weight loss of up to 5 kg in one year.[clindiabetesendo.biomedcentral.com] Stones Various Nephritis and Vasculitis Acute Urate Nephropathy In many cases, urinalysis can detect diseases that may not show any early symptoms through the discovery of increased[kidneyandhypertensioncare.com]

    Missing: Mutation in the EIF2AK3 Gene Onset of Renal Dysfunction in Early Childhood
  • Acute Myocardial Infarction

    This negative prognostic impact of increased glucose levels remained significant in multivariate adjustment and was not influenced even after adjustment for the presence or[ncbi.nlm.nih.gov] This risk can be reduced by ensuring your blood pressure, cholesterol levels and blood sugar (glucose) levels are well controlled. Family history.[patient.co.uk] Risk factors Non-modifiable risk factors for atherosclerosis include increasing age, being male, family history of premature CHD, premature menopause.[patient.info]

    Missing: Mutation in the EIF2AK3 Gene Onset of Renal Dysfunction in Early Childhood
  • Hemochromatosis

    F-FDG PET/CT was performed as routine follow-up and showed a pathological finding of homogeneous increased liver glucose metabolism.[ncbi.nlm.nih.gov] Arthropathy, hepatic fibrosis, glucose intolerance, and increased skin pigmentation are frequent.[orpha.net] Signs and symptoms will vary from person to person and may include: Fatigue, weakness Abdominal pain Joint pain Increased blood glucose levels and diabetes Liver dysfunction[labtestsonline.org]

    Missing: Mutation in the EIF2AK3 Gene Onset of Renal Dysfunction in Early Childhood

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