Glycosuria: Causes & Reasons

2.1

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Possible Causes for glycosuria

Diabetes Mellitus

He attributed the decrease in urinary sugar to a ‘temporary toxic renal effect’ (he had been expecting a compensating increase in glycosuria). [dx.doi.org]

Subsequently, hyperglycemia and glycosuria, but not ketonuria, occured. [pediatrics.aappublications.org]

[…] weight loss is specific for IDDM; type 2 patients rarely have either Severe fasting hypoglycemia is due to cessation of glycogen storage in fat and muscle Glycosemia causes glycosuria [pathologyoutlines.com]

Endocrine Dysfunction

Abstract Infertility can be frustrating for patients and physicians. Endocrine dysfunction can impair fertility and alter pregnancy outcome. Once the diagnosis is secured, most endocrine disorders are reversible or can be adequately managed to restore fertility and decrease associated pregnancy complications.[…] [ncbi.nlm.nih.gov]

Cushing Syndrome

Cushing syndrome (CS) in children is a rare disorder that is most frequently caused by an adrenal tumour or a pituitary corticotrophin-secreting adenoma. The management is challenging and requires an individualised approach and multidisciplinary care. We present the case of a 23-month-old female child with a history[…] [ncbi.nlm.nih.gov]

Renal Tubular Acidosis

He was also found to have hyperchloraemic metabolic acidosis with hypokalaemia, hypophosphataemia, phosphaturia and glycosuria, which favoured a diagnosis of proximal renal [ncbi.nlm.nih.gov]

The blood salicylate level was undetectable, and a urinalysis showed glycosuria, proteinuria and elevated beta-2 microglobulin and n-acetyl glucosamine levels, with a normal [ncbi.nlm.nih.gov]

Urinalysis showed inappropriate alkaline urine (urinary PH: 7), glycosuria with normal blood glucose, phosphaturia and uricosuria. [ncbi.nlm.nih.gov]

Familial Renal Glucosuria

Sodium-glucose transport proteins Media related to Renal glycosuria at Wikimedia Commons [en.wikipedia.org]

Pregnant women with familial renal glycosuria can be at risk of profound polyuria during pregnancy due to the associated increase in glycosuria. [ncbi.nlm.nih.gov]

Etiologically, renal glycosuria is of 3 types-benign renal glycosuria, glycosuria with diabetes mellitus (including gestational diabetes) and tubular defects (Fanconi syndrome [ncbi.nlm.nih.gov]

Nephropathic Cystinosis

Renal tubular disease is usually present causing aminoaciduria, glycosuria and hypokalemia. Cysteine deposition is most evident in the conjunctiva and cornea. [en.wikipedia.org]

Renal tubular disease, aminoaciduria, glycosuria, and hypokalemia are usually present. [whonamedit.com]

[…] diagnosis is based on blood and urine analysis showing features of Fanconi syndrome (metabolic acidosis, hypokalemia, hyponatremia, hypophosphatemia, hyperaminoaciduria, glycosuria [orpha.net]

Cystinosis

The de Toni-Fanconi syndrome* is a clinical constellation characterized by resistant rickets, acidosis, glycosuria, hyperamino-aciduria, and organic aciduria. [doi.org]

All had nephropathic infantile-type cystinosis with evidence of proximal tubulopathy, with glycosuria and renal phosphate wasting. [ncbi.nlm.nih.gov]

Diagnostic methods The diagnosis is based on blood and urine analysis showing features of Fanconi syndrome (metabolic acidosis, hypokalemia, hyperaminoaciduria, glycosuria [orpha.net]

Oculocerebrorenal Syndrome

Glycosuria. Lowe noted the absence of glycosuria in his first three patients, even when blood glucose levels were increased to 150 mg/dl in two patients ( 1 ). [cjasn.asnjournals.org]

a 2-month-old infant, was examined because of bilateral congenital cataracts and was also found to have bilateral glaucoma, albuminuria, and minimal glycosuria. [doi.org]

[…] intestinal carbohydrate absorption ( Glucose-galactose malabsorption, Sucrose intolerance ) - pyruvate metabolism and gluconeogenesis ( PCD, PDHA ) - Pentosuria - Renal glycosuria [wikidoc.org]

Renal Tubular Dysfunction

Our patients (5 women and 2 men) developed renal tubular dysfunction, with hypophosphatemia, normoglycemic glycosuria, proteinuria, and decrease of creatinine clearance. [ncbi.nlm.nih.gov]

Estimated glomerular filtration rate (eGFR) and markers of tubular damage to assess tubular dysfunction (fractional excretion of phosphate and uric acid, glycosuria, and proteinuria [ncbi.nlm.nih.gov]

[…] of 90 patients with two successive dual X-ray absorptiometry scans after evaluation of serum and urinary parameters (proteinuria, albuminuria, phosphaturia, uricosuria, glycosuria [ncbi.nlm.nih.gov]

Wilson Disease

Wilson disease (OMIM # 277900) is a autosomal recessive disorder characterized by accumulation of copper in liver and brain. The accumulation of copper resulting in oxidative stress and eventually cell death. The disease has an onset in a childhood and result in a significant neurological impairment or require lifelong[…] [ncbi.nlm.nih.gov]

Pentosuria

Positive Benedict’s test for urine signifies Glycosuria. Glycosuria is a non-specific term. [usmle.biochemistryformedics.com]

Definitions from The Century Dictionary. noun A form of glycosuria in which the excreted sugar is a pentose. from Wiktionary, Creative Commons Attribution/Share-Alike License [wordnik.com]

He emphasized the likelihood of their being mistakenly classified as examples of renal glycosuria unless the ty[ill] of urinary sugar is determined. [jamanetwork.com]

Fanconi Renotubular Syndrome

Defects in proximal tubular function can be isolated (e.g. isolated renal glycosuria, aminoacidurias, or hypophosphataemic rickets) or generalized. [oxfordmedicine.com]

It is usually characterized by severe and fatal progression accompanied by type II proximal renal tubular dysfunction, as evidenced by glycosuria, proteinuria, electrolyte [ncbi.nlm.nih.gov]

It is characterized by aminoaciduria, normoglycemic glycosuria, tubular proteinuria without hematuria, metabolic acidosis without anion gap and excessive urinary excretion [ncbi.nlm.nih.gov]

Adult Fanconi Syndrome

Defects in proximal tubular function can be isolated (e.g. isolated renal glycosuria, aminoacidurias, or hypophosphataemic rickets) or generalized. [oxfordmedicine.com]

Renal Glycosuria Synonyms of Renal Glycosuria Benign Glycosuria Familial Renal Glycosuria Nondiabetic Glycosuria Primary Renal Glycosuria Renal Glucosuria Subdivisions of [rarediseases.org]

phosphaturia, renal tubular acidosis (RTA) type 2 (proximal), hypophosphataemic rickets (children) or osteomalacia (adults), and renal glycosuria. [ 2, 3 ] Epidemiology [patient.info]

Acquired Fanconi Syndrome

[…] tubular reabsorption of phosphate (%TRP), increased fractional excretion of potassium (FEK) and uric acid (FEUA), low-molecular-weight proteinuria, panaminoaciduria and glycosuria [ncbi.nlm.nih.gov]

Defects in proximal tubular function can be isolated (e.g. isolated renal glycosuria, aminoacidurias, or hypophosphataemic rickets) or generalized. [oxfordmedicine.com]

Glycosuria and aminoaciduria were also observed (Table 2 ). Therefore, a diagnosis of Fanconi syndrome was made. [bmcnephrol.biomedcentral.com]

Proximal Renal Tubular Acidosis

[…] a solitary defect, but is usually associated with a more generalised dysfunction of the proximal tubular cells called Fanconi syndrome where there is also phosphaturia, glycosuria [en.wikipedia.org]

Proximal tubular dysfunction, resembling adult Fanconi's syndrome, was suggested by an increased urinary loss of phosphate and urate and glycosuria. [archinte.ama-assn.org]

Lactosuria

*The ’ occur, whereas 42 (33%) never had glycosuria at any time. [kundoc.com]

List of possible causes of Glycosuria or similar symptoms may include: 2 Atypical Werner syndrome (Glycosuria) Cataracts (Glycosuria) Cataract, juvenile, with microcornea [familydiagnosis.com]

Glycosuria is the excretion of glucose into the urine. [en.wikipedia.org]

Cutaneous Candidiasis

[…] in the immediate neonatal period and/or laboratory signs of sepsis such as an elevated leukocyte count with an increase in immature forms or persistent hyperglycemia and glycosuria [ncbi.nlm.nih.gov]

Disorders of Amino-Acid Transport

[…] precipitate within lysosomes in proximal tubules CLINICAL ISSUES Epidemiology Incidence Rare (68 cases reported as of 2000) Presentation Fanconi syndrome (acquired) Normoglycemic glycosuria [basicmedicalkey.com]

In the case presented here, testing for Fanconi syndrome was not performed although the patient was noted to have glycosuria in the setting of normal serum glucose. [theisn.org]

Short IA, Smith JP: Myelomatosis associated with glycosuria and aminoaciduria. Scott Med J 489-93, 1959 28. [docslide.net]

Cadmium Poisoning

The effects of cadmium proximal renal function are characterized by increased cadmium in the urine, proteinuria (primarily Beta-2-microglobulin), aminoaciduria, glycosuria [pathopedia-india.com]

In the final stages of cadmium nephropathy, glycosuria, wasting of calcium and phosphate, and altered calcium metabolism with secondary effects on the skeleton of osteoporosis [atsdr.cdc.gov]

Renal dysfunction affects calcium, vitamin D, phosphorus and sodium levels, resulting in proteinuria, glycosuria, renal hypertension and other metabolic disorders. [arltma.com]

Fanconi-Bickel Syndrome

1 Glycosuria and hyperglycemia in the neonatal period as the first clinical sign of Fanconi-Bickel syndrome. ( 28493372 ) 2017 2 Hepatocellular Carcinoma in Fanconi-Bickel [malacards.org]

Glycosuria[?] GM2 gangliosidosis, 0 variant[?] GM2-gangliosidosis, B, B1, AB variant[?] Gms syndrome[?] Goldberg Bull syndrome[?] Goldberg syndrome[?] [encyclopedia.kids.net.au]

Glycosuria and ketonuria occur after breakfast and therefore may be confused with diabetes mellitus. Treatment : adequate diet and avoidance of fasting hypoglycaemia. [patient.info]

Hypoglycemia

Critical illnesses: Cardiac, hepatic, and renal diseases; sepsis with multiorgan failure Exercise (in patients with diabetes treated with diabetes medications) Pregnancy Renal glycosuria [emedicine.com]

Carbamate Poisoning

There were 13 men and 10 women. 10 subjects had euglycemia associated with glycosuria; 6 subjects had transient glycosuria with hyperglycemia (defined as random glucose over [ncbi.nlm.nih.gov]

RESULTS: Sixteen out of the 23 subjects (69%) demonstrated transient glycosuria. [ncbi.nlm.nih.gov]

The occurrence and duration of glycosuria, its magnitude, associated hyperglycemia if any, and correlation thereof were recorded. [ncbi.nlm.nih.gov]

Maturity-Onset Diabetes of the Young

A 7-year-old boy presented with asymptomatic hyperglycemia ranging between 6.2 and 10.1 mmol/L and glycosuria for nearly a year. [ncbi.nlm.nih.gov]

Investigations revealed hyperglycemia, glycosuria, and ketonuria without acidosis. Pancreatic antibodies were negative. She responded well to subcutaneous insulin. [ncbi.nlm.nih.gov]

Case 1: a 4-yr-old girl referred for glycosuria presented hemoglobin A1c (HbA1c) of 6.6%. [ncbi.nlm.nih.gov]

Arthrogryposis - Renal Dysfunction - Cholestasis Syndrome

Renal tubular dysfunction ranges from isolated renal tubular acidosis to complete Fanconi syndrome (polyuria, aminoaciduria, glycosuria, phosphaturia and bicarbonate wasting [rarediseases.info.nih.gov]

Urine analysis revealed 6 cases(85 % ) with proteinuria, 3(43 % ) with hematuria, 5(71 % ) with glycosuria, 2(29 % ) with phosphaturia and 2(29 % ) with calciuria. [chikd.org]

Urinalysis showed proteinuria, glycosuria, and aminoaciduria. The blood urea nitrogen level was 6.4mg/dl, the creatinine 0.4mg/dl and the total cholesterol 109mg/dl. [ci.nii.ac.jp]

Acute Cystitis

باڈی بلڈنگ Frigidity, Inhibited sexual desire عورتوں میں جنسی خواہش کی کمی Gastritis Dard shakam, Pain ka dard ورم معدہ, پیٹ پیڑا General Debility Kamzori, Naqqahat کمزوری Glycosuria [jariboti.pk]

False-negative specimens can be caused by hypertonic urine (as determined by high specific gravity), glycosuria, and urobilinogen. [microbiologybook.org]

Alcoholic Ketoacidosis

On admission, blood glucose level was normal or moderately elevated, glycosuria was absent or trivial, and alcohol had disappeared from blood, but ketoacidosis was sometimes [dx.doi.org]

The dissociation of severe ketosis from glycosuria and hyperglycemia in these patients raises important questions concerning coupling of ketogenesis to gluconeogenesis. [diabetes.diabetesjournals.org]

Urinary Tract Infection

False-negative specimens can be caused by hypertonic urine (as determined by high specific gravity), glycosuria, and urobilinogen. [microbiologybook.org]

Differences in urine pH and osmolality and pregnancy‐induced glycosuria and aminoaciduria may facilitate bacterial growth. [doi.org]

Vaginal Candidiasis

It is most often associated with pregnancy, glycosuria, diabetes mellitus, or use of antibiotics. [medical-dictionary.thefreedictionary.com]

Acute Interstitial Nephritis

There may also be other clinical manifestations of tubular injury abnormalities depending on the segment affected (such as glycosuria, bicarbonaturia, tubular acidosis, inability [revistanefrologia.com]

On urinalysis there was 3 proteinuria, trace blood and 2 glycosuria. [omicsonline.org]

Renal Cysts and Diabetes Syndrome

Renal cysts Renal parenchymal disease Rudimentary uterus Scarred glomerular tufts Structural kidney abnormalities Vagina aplasia Metabolic Abnormality Diabetes mellitus Glycosuria [datagenno.com]

Cerebral cortical atrophy ; Decreased numbers of nephrons ; Elevated hepatic transaminase ; Elevated serum creatinine ; Epididymal cyst ; Exocrine pancreatic insufficiency ; Glycosuria [mousephenotype.org]