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13 Possible Causes for Gonadotrophin Increased, Widely Spaced Nipples

  • Turner Syndrome

    Gonadotrophins are later suppressed to normal or near-normal levels, and then increase to menopausal levels after the age of 10 years.[] […] intermamillary distance Wide-spaced nipples Widely spaced nipples Widely-spaced nipples [ more ] 0006610 30%-79% of people have these symptoms Anxiety Excessive, persistent[] Other characteristics, like widely spaced nipples or low-set ears, also may lead to a suspicion of Turner syndrome.[]

  • Klinefelter Syndrome

    Furthermore he had increased gonadotrophin levels and an extreme oligoasthenoteratozoospermia (OAT).[] On physical exam she was noted to have a low hairline, wide spaced nipples. What would be the best first study to perform on this patient?[] […] are increased testosterone is decreased Differential Double Y males (47XYY), Fragile X syndrome, Marfan syndrome Treatment Medical management testosterone replacement may[]

  • 46,XX Ovarian Dysgenesis-Short Stature Syndrome

    Although men with KS have dysgenetic testes (rarely larger than 6-10 mL) and high gonadotrophin levels, they do not appear to have a high risk of gonadal cancers.[] […] without hormonal treatment, average height is 145cm); ovarian dysgenesis (streak ovary); this is the most common cause of primary amenorrhea; infertility; shield chest with widely-spaced[] spaced nipples, sexual infantilism.[]

  • Renal Malrotation

    Gonadotrophins are later suppressed to normal or near-normal levels, and then increase to menopausal levels after the age of 10 years.[] Chest - broad chest, pectus excavatum, inverted, hypoplastic, widely-spaced nipples. Joints - cubitus valgus, congenital hip dislocation.[] Gonadotrophins: LH and FSH may be elevated in untreated patients aged younger than 4 years.[]

  • Absent Thumb - Short Stature - Immunodeficiency Syndrome

    Despite testosterone substitution therapy, the size of the testes and penis only increased during puberty.[] spaced nipples, and webbed neck?[] spaced nipples, renal abnl (horseshoe or collecting system abnl) Term VATER/VACTERL association Definition Vertebral anomalies, Anal atresia, Cardiac anomalies, TE fistula[]

  • 45,X/46,XY Mixed Gonadal Dysgenesis

    Serum gonadotrophin (GnH) levels were basically high in the postopubertal patients and the responses of GnH to LH-RH were significantly increased in the prepubertal patients[] spaced nipples 758.6 Excludes pure gonadal dysgenesis ( 752.7 ) Applies To Ovarian dysgenesis Turner's syndrome XO syndrome ICD-9-CM Volume 2 Index entries containing back-references[] […] sterile females due to monosomy for x chromosome; the ovaries are rudimentary or missing; other abnormalities include short stature, webbed neck, and a broad chest with widely[]

  • Primary Male Hypogonadism

    However, as the testes are impaired or missing, they are not able to respond to the increased levels of gonadotrophins and little or no testosterone is produced.[] Short stature Webbed neck Shield chest w/ wide spaced nipples Cubitus valgus What is XX gonadal dysgenesis?[] In some patients with primary hypogonadism, testosterone levels may be within the normal range, but the increased LH and FSH indicates that the pituitary gland is trying to[]

  • Aromatase Deficiency

    […] treatments of gonadotrophin-releasing hormone antagonists.[] spaced nipples, cubitus valgus ;, nail dysplasia, short fourth metacarpals/metatarsals High arched palate, low-set posterior hairline Webbed neck : skin folds along the side[] On the other hand, precocious increase in ovarian aromatase/estrogen results in precocious puberty, including early epiphyseal closure and short stature ( 46 ).[]

  • ROHHAD Syndrome

    Increased endorphin production leads to increased prolactin production and inhibition of gonadotrophin-releasing hormone and thyroid-stimulating hormone release.[] […] or weblike neck Low-set ears Broad chest with widely spaced nipples High, narrow roof of the mouth (palate) Arms that turn outward at the elbows Fingernails and toenails[] […] other abnormal fluid collections (edema) Heart abnormalities Abnormal kidneys At birth or during infancy Signs of Turner syndrome at birth or during infancy may include: Wide[]

  • 48,XXYY Syndrome

    Where Klinefelter’s syndrome is suspected, blood tests will be carried out to assess levels of testosterone and gonadotrophins ( luteinising hormone and follicle stimulating[] Important characteristics to remember include short stature, webbed neck, broad chest with widely spaced nipples, amenorrhea, and coarctation of the aorta.[] It is thought that older parents may be more likely to have a child with Klinefelter’s syndrome; this is probably because the risk of chromosomal abnormalities increases with[]

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