Gonadotropin Levels Increased: Causes & Reasons

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Possible Causes for Gonadotropin Levels Increased

Leydig Cell Hypoplasia

[…] circulating gonadotropin level Abnormality of the genitourinary system Hypergonadotropic hypogonadism Abnormality of the nervous system Increased circulating gonadotropin [familydiagnosis.com]

It is biochemically characterized by low testosterone levels, without elevated precursors, even after stimulation with human chorionic gonadotropin, and LH increased levels [endocrine-abstracts.org]

Gonadotropin levels were elevated, and testosterone was low and failed to increase after stimulation with human chorionic gonadotropin. [ncbi.nlm.nih.gov]

Variants of Klinefelter Syndrome

Klinefelter syndrome is distinguished by many clinical features, such as infertility, high gonadotropin and low testosterone levels, increased height, and sparse body and [onlinelibrary.wiley.com]

Hypergonadotropic Hypogonadism-Cataract Syndrome

[…] syndrome type 1 (Increased circulating gonadotropin level) Blepharophimosis, ptosis, and epicanthus inversus syndrome type 2 ... ... [familydiagnosis.com]

[…] circulating gonadotropin level 59 32 hallmark (90%) Very frequent (99-80%) HP:0000837 7 primary amenorrhea 59 32 hallmark (90%) Very frequent (99-80%) HP:0000786 8 hypergonadotropic [malacards.org]

The decreased sex hormone level stimulates increased production of gonadotropins due to diminished negative feedback mechanisms. [clinicaladvisor.com]

Testicular Choriocarcinoma

We report on a 16-year-old boy with metastatic testicular choriocarcinoma, increased levels of human chorionic gonadotropin and profound hyperthyroidism bordering on thyroid [ncbi.nlm.nih.gov]

Manifestations of choriocarcinoma include: Increased HCG (human chorionic gonadotropin) levels beyond the first trimester and excessively increased HGH during early pregnancy [cancerwall.com]

This type of tumor increases blood levels of HCG (human chorionic gonadotropin). [cancer.org]

Central Precocious Puberty

Approximately 1 year after the surgery, the patient's breast development persisted, bone age progressed rapidly, and gonadotropin levels increased in a GnRH test. [ncbi.nlm.nih.gov]

Case 2 had low gonadotropins but increased estrogen levels. [medical-case-reports.imedpub.com]

[…] in pituitary gonadotropin levels. [touchendocrinology.com]

Blepharophimosis-Epicanthus Inversus-Ptosis Syndrome

[…] circulating gonadotropin level Microcornea Microphthalmia Telecanthus Wide nasal bridge (Source: Blepharophimosis, Ptosis, and Epicanthus Inversus Syndrome Type 2; Genetic [dovemed.com]

[…] circulating gonadotropin level Elevated gonadotropins Elevated serum gonadotropins Gonadotropin excess [ more ] 0000837 Microcornea Cornea of eye less than 10mm in diameter [rarediseases.info.nih.gov]

[…] individuals: Abnormality of the breast Abnormality of the hair Amenorrhea Cupped ear Epicanthus inversus Female infertility High palate Hypermetropia Hypoplasia of the uterus Increased [dovemed.com]

Hypogonadotropic Hypogonadism Type 21

After administration of human chorionic gonadotropin treatment, androgen levels increased and ejaculation started although in small amounts ( Conclusion: Men with 47,XYY syndrome [endocrine-abstracts.org]

Once they stopped gonadotropin therapy, testicle sizes stopped increasing, and testosterone levels dropped to near zero. [ajandrology.com]

Bonaccorsi et al. presented three cases of male infertility resulting from 21-hydrox-ylase deficiency with low serum gonadotropin levels that were unresponsive to GnRH stimulation [78stepshealth.us]

Blighted Ovum

may increase. [fertilityauthority.com]

(hCG) may increase. [webmd.com]

Many women with blighted ovum believe their pregnancy is progressing normally, since their levels of human chorionic gonadotropin (hCG), a hormone produced during pregnancy [fertilityauthority.com]

Complete Androgen Insensitivity Syndrome

Serum anti-Müllerian hormone (AMH) levels are normal or increased. [orpha.net]

The typical hormone profile is increased basal luteinizing hormone (LH) and testosterone levels in adults, and increased testosterone levels in infants following human chorionic [orpha.net]

gonadotropin (hCG) stimulation. [orpha.net]

Germ Cell Tumor

Tumor marker levels in blood serum were elevated. The alpha-fetoprotein level was increased 5-fold; human chorionic gonadotropin 20-fold. [ncbi.nlm.nih.gov]

Although the pituitary gonadotropin levels had remained low during the period with no tumor growth, the gonadotropin levels were elevated and had continued to increase at [ncbi.nlm.nih.gov]

[…] alphafetoprotein (AFP) or beta-human chorionic gonadotropin serum levels. [ncbi.nlm.nih.gov]

Anorchia

Decreased serum testosterone levels Low serum testosterone level Low serum testosterone levels [ more ] 0040171 Increased circulating gonadotropin level Elevated gonadotropins [rarediseases.info.nih.gov]

Human chorionic gonadotropin (hCG) stimulation test failed to increase testosterone levels. Peripheral blood karyotype was 46, XY. [ncbi.nlm.nih.gov]

[…] of people have these symptoms Abnormal vas deferens morphology 0012872 Absent external genitalia 0000042 Absent testis Absent testes 0010469 Decreased serum testosterone level [rarediseases.info.nih.gov]

Leydig Cell Tumor

Almost all of these boys present with isosexual precocious pseudopuberty associated with increased testosterone, low gonadotropin levels and a testis mass. [ncbi.nlm.nih.gov]

This type of tumor increases blood levels of HCG (human chorionic gonadotropin). [cancer.org]

Prepubertal boys with isosexual precocious pseudopuberty, an isolated testis mass, increased testosterone and low or normal gonadotropin levels can reliably be diagnosed with [ncbi.nlm.nih.gov]

XYY Syndrome

[…] circulating gonadotropin level Elevated gonadotropins Elevated serum gonadotropins Gonadotropin excess [ more ] 0000837 Increased serum testosterone level 0030088 Macroorchidism [rarediseases.info.nih.gov]

[…] testes Undescended testis [ more ] 0000028 Dysgenesis of the cerebellar vermis 0002195 Hydrocephalus Too much cerebrospinal fluid in the brain 0000238 Hypospadias 0000047 Increased [rarediseases.info.nih.gov]

Complete Hydatidiform Mole

No malformations were observed, fetal karyotype was normal and β-human chorionic gonadotropin levels were increased (>100,000 IU/ml). [ncbi.nlm.nih.gov]

A 34-year-old woman presented at 20 weeks of gestation with increased levels of serum beta human chorionic gonadotropin (beta-HCG) at 4.74 multiples of the median (310277.7 [ncbi.nlm.nih.gov]

When you’re pregnant, levels of the hormone HCG ( human chorionic gonadotropin ) increase. [webmd.com]

Hyperemesis Gravidarum

Pregnancy frequently causes nausea and vomiting; the cause appears to be rapidly increasing levels of estrogens or the beta subunit of human chorionic gonadotropin (beta-hCG [merckmanuals.com]

Hypogonadotropic Hypogonadism Type 18

[…] circulating gonadotropin level Deformed humeral heads Arachnodactyly Reduced bone mineral density Premature ovarian insufficiency Pulmonary fibrosis Decreased fertility Gonadal [mendelian.co]

Once they stopped gonadotropin therapy, testicle sizes stopped increasing, and testosterone levels dropped to near zero. [ajandrology.com]

Circulating levels of both gonadotropins increase to attain peak levels by weeks 20–25 and then decrease toward term ( 7 – 9 ). [frontiersin.org]

Isolated Follicle Stimulating Hormone Deficiency

About 30% of women with secondary amenorrhea have normal levels of gonadotropins. [ebmconsult.com]

Serum FSH & LH level in a patient with isolated gonadotropin deficiency after rFSH 15 Serum estradiol level showed a gradual increase to a maximum on day 15, the day of maximum [gfmer.ch]

Suspected hypogonadism Men: Increased levels of serum FSH and luteinizing hormone (LH) suggest primary testicular failure. [ebmconsult.com]

Familial Testotoxicosis

Diagnostic methods Patients display increased serum testosterone levels (typically 3- 20 nmol/l) and decreased secretion of gonadotropins, even after stimulation with luteinizing [orpha.net]

Gonadotropin levels reach a nadir at 6 months of life, although females may retain variable degrees of GnRH release during the first few years of life. [oncohemakey.com]

Generally, peripheral effects of these sex steroids do not occur during this “mini puberty,” possibly due to the transient nature of the sex steroid increase. [oncohemakey.com]

Male Pseudohermaphroditism

Neither T nor its precursors increased with human chorionic gonadotropin (hCG) stimulation. [ncbi.nlm.nih.gov]

Levels of gonadal steroids in peripheral blood suggested low activity of steroidogenesis which was consistent with the high levels of gonadotropins found. [ncbi.nlm.nih.gov]

Invasive Hydatidiform Mole

[…] chorionic gonadotropin (hCG) levels after evacuation of a hydatidiform mole. [orpha.net]

A very high level of beta human chorionic gonadotropin (β-hCG), a hormone made by the body during pregnancy. A large tumor in the uterus. [northshore.org]

Clinical description Indicative signs of the disease are persistent unexplained metrorrhagia or secondary increase, stagnation, or non-normalization at 6 months of total serum [orpha.net]

Testicular Embryonal Carcinoma and Seminoma

An increased rate of cryptorchidism, increased gonadotropin levels and genetic instability are possible pathways. [ncbi.nlm.nih.gov]

Serum beta-human chorionic gonadotropin (beta-hCG) levels were slightly increased. [ncbi.nlm.nih.gov]

Some seminomas can increase blood levels of a protein called human chorionic gonadotropin (HCG). [stanfordhealthcare.org]

Precocious Puberty

When there are high-amplitude pulses or release of the GnRH, it causes the pulsatile increase in the levels of the pituitary gonadotropin-luteinizing hormone or LH and follicle-stimulating [symptoma.com]

[…] in pituitary gonadotropin levels. [touchendocrinology.com]

[…] years, to identify girls subsequently requiring treatment to block precocious puberty.1,8,9 In both sexes, the central cause of precocious puberty is demonstrated by an increase [touchendocrinology.com]

Ovarian Hyperstimulation Syndrome

Late ovarian hyperstimulation syndrome occurs 10 or more days after human chorionic gonadotropin trigger and reflects increased endogenous human chorionic gonadotropin levels [ncbi.nlm.nih.gov]

Causes It is usually caused after the administration of gonadotropins or if endogenous LH levels increase naturally. [invitra.com]

This transient increase of gonadotropin levels after birth is known as the mini-puberty (12). [degruyter.com]

Hypergonadotropic Hypogonadism - Partial Alopecia

[…] circulating gonadotropin level 60 33 hallmark (90%) Very frequent (99-80%) HP:0000837 9 primary amenorrhea 60 33 hallmark (90%) Very frequent (99-80%) HP:0000786 10 absence [malacards.org]

[…] frequent (99-80%) HP:0000823 6 osteoporosis 60 33 hallmark (90%) Very frequent (99-80%) HP:0000939 7 cryptorchidism 60 33 hallmark (90%) Very frequent (99-80%) HP:0000028 8 increased [malacards.org]

Hydatidiform Mole

No malformations were observed, fetal karyotype was normal and β-human chorionic gonadotropin levels were increased (>100,000 IU/ml). [ncbi.nlm.nih.gov]

Both pregnancies were evacuated by suction curettage, and the patient was followed by serial monitoring of beta-human chorionic gonadotropin levels. [ncbi.nlm.nih.gov]

An intrauterine device should not be inserted until the patient achieves normal gonadotropin levels because of the risk of uterine perforation. Because of increased risk [slideshare.net]

Hypogonadotropic Hypogonadism Type 8

Once they stopped gonadotropin therapy, testicle sizes stopped increasing, and testosterone levels dropped to near zero. [ajandrology.com]

[…] sex hormone levels and has the potential to improve production of natural gonadotropins and improve fertility. [ema.europa.eu]

The deficiency in gonadotropins decreases the plasma AMH levels, and a combination of no testosterone increase and gonadotropin deficiency in HH probably explains the difficulties [journals.plos.org]

Frasier Syndrome

While her serum estradiol level was gradually increasing annually, gonadotropin level was constantly extremely high, and her appearance was still prepubertal. [ncbi.nlm.nih.gov]

[…] circulating gonadotropin level Elevated gonadotropins Elevated serum gonadotropins Gonadotropin excess [ more ] 0000837 Primary amenorrhea 0000786 Proteinuria High urine [rarediseases.info.nih.gov]

Decreased serum estradiol 0008214 Focal segmental glomerulosclerosis 0000097 Gonadal dysgenesis with female appearance, male 0008723 Hypergonadotropic hypogonadism 0000815 Increased [rarediseases.info.nih.gov]

Vomiting of Pregnancy

Increase in blood thyroxine levels, which has been documented in 70 percent of hyperemesis gravidarum cases, according to the HER Foundation A multiple pregnancy (twins, [everydayhealth.com]

Read: Estrogen Types Before, During and After Pregnancy Increased hCG: Levels of human chorionic gonadotropin in pregnant women are high, although it is not proven how they [health.in4mnation.com]

Pregnancy frequently causes nausea and vomiting; the cause appears to be rapidly increasing levels of estrogens or the beta subunit of human chorionic gonadotropin (beta-hCG [merckmanuals.com]

Testicular Embryonal Carcinoma

This type of tumor increases blood levels of HCG (human chorionic gonadotropin). [cancer.org]

Association of embryonal carcinomas with syncytiotrophoblastic giant cells may cause increases in serum human chorionic gonadotropin (hCG) levels. [emedicine.medscape.com]

There may be elevations in serum human chorionic gonadotropin (hCG) and alpha fetoprotein (AFP) levels but it would be in association with other tumors, (e.g. yolk sac tumor [humpath.com]

Hypogonadism

Expert commentary: The present data indicate that antiestrogens are able to increase testosterone levels without changing gonadotropins or even increasing them. [ncbi.nlm.nih.gov]

This is an estrogen receptor modulator that increases gonadotropin levels and stimulates testosterone and sperm production. Few studies are as yet available, however. [symptoma.com]

As a result, the brain increases the amount of the gonadotropins signals, which causes a higher-than-normal level of these signals in the blood. [my.clevelandclinic.org]