Gouty Tophus: Causes & Reasons

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Possible Causes for Gouty Tophus

Gouty Arthritis

The case presented here indicates the possibility of pathologic rupture of the ACL associated with gouty tophus infiltration of that ligament. Level of evidence IV. [ncbi.nlm.nih.gov]

Gouty tophus presenting at a soft tissue mass diagnosed by fine-needle aspiration: a case report. Diagn Cytopathol. 1996 ; 15: 246 – 9. [dx.doi.org]

Histology evaluation revealed gouty arthritis with the presence of tophi in the synovium, soft tissue, and ACL tissue. [ncbi.nlm.nih.gov]

Gout

The surgery combined with decreasing trioxypurine treatment can improve the treatment outcome of gouty tophus. [ncbi.nlm.nih.gov]

Histopathology confirmed the excised tissue as gouty tophus. [ncbi.nlm.nih.gov]

Gouty tophus presenting at a soft tissue mass diagnosed by fine-needle aspiration: a case report. Diagn Cytopathol. 1996 ; 15: 246 – 9. [doi.org]

Chronic Gouty Nephropathy

274.00 chronic (without mention of tophus (tophi)) 274.02 with tophus (tophi) 274.03 Gout, gouty 274.9 with tophi (tophus) 274.03 arthropathy 274.00 chronic (without mention [healthprovidersdata.com]

tophus, acute gouty arthritis, chronic gouty arthritis, gouty nephropathy, urinary calculus, renal dysfunction, coronary artery disease and ischemic heart disease or the [patentscope.wipo.int]

Rao et al. [7] reported a case of gouty tophus with normal serum uric acid level. [ijhas.in]

Familial Reactive Perforating Collagenosis

Tophus Pathology of Pseudoxanthoma Elasticum #dermatopathology Pathology of Elastosis Perforans Serpiginosa - 10 Important Facts Pathology of Gouty Tophus Pathology of Basaloid [pinterest.co.kr]

[…] dermatopathology #dermpath Pathology of Rippled-Pattern Sebaceoma Pathology of Papillary Eccrine Adenoma Pathology of Hidradenitis Suppurativa #dermatopathology Pathology of Gouty [pinterest.co.kr]

Acute Polyarticular Gout

Synonym: monosodium urate deposition disease tophus ; Symptoms Most hyperuricemic people are asymptomatic between acute attacks. [medical-dictionary.thefreedictionary.com]

The left elbow reveals a gouty tophus. The joint is slightly red, tender, warm to touch, and has a palpable effusion. [ahcmedia.com]

Gouty tophus at the lateral canthus. Arch Ophthalmol. 2003 Aug. 121(8):1195-7. [Medline]. Fishman RS, Sunderman FW. Band keratopathy in gout. [emedicine.medscape.com]

Crystal Arthropathy

Radiologic case study: Gouty tophus involving the distal quadriceps tendon. Orthopedics. 2004;27:90-92. Miller LJ, Pruett SW, Losada R, et al. [appliedradiology.com]

Formation and Gouty Inflammation 6 Gout: Epidemiology and Risk Factors 7 Genetics of Gout 8 Diagnosis of Gout 9 Clinical Features of Gout 10 Treatment of Acute Gout 11 Diet [elsevier.com]

Synonym: monosodium urate deposition disease tophus ; Symptoms Most hyperuricemic people are asymptomatic between acute attacks. [medical-dictionary.thefreedictionary.com]

Familial Normophosphatemic Tumoral Calcinosis

Gouty tophus usually develops in a patient with a history of recurrent attacks of acute gouty arthritis. [documents.tips]

Arthritis Rheum 26, 98â101. 11 Chaoui A, Garcia J, Kurt AM (1997) Gouty tophus simu- lating soft tissue tumor in a heart transplant patient. [documents.tips]

The calcific deposits may be solitary or multiple, variable in size and occasionally, it may be mistaken clinically for malignancy or gouty tophus. [documents.tips]

Cricoarytenoid Ankylosis

Arch Otolaryngol 102: 27–29 PubMed CrossRef Google Scholar Marion RB, Alperin JE, Maloney WH (1972) Gouty tophus of the true vocal cord. [link.springer.com]

Laryngoscope 90: 296–303 PubMed CrossRef Google Scholar Goodman M, Montgomery W, Minette L (1976) Pathologic findings in gouty cricoarytenoid arthritis. [link.springer.com]

Foreign Body in Subcutaneous Tissue

Examples of granulomas due to endogenous material: Calcium deposits: Urates- Gouty Tophus - Path Quiz Case 57 Oxalate. : Keratin and hair : Granulomatous inflammation is present [histopathology-india.net]

Gouty Tophus

The diagnosis was confirmed as a gouty tophus without performing a nasal subdermal exploration. [ncbi.nlm.nih.gov]

Abstract To examine the role of matrix proteins in the formation of gouty tophus, we analyzed the crystalline components and matrix proteins in a gouty tophus from a patient [ncbi.nlm.nih.gov]

We describe the imaging and pathologic features of a case of intratendinous patellar gouty tophus incidentally discovered in a patient with knee pain. [ncbi.nlm.nih.gov]

Pseudogout

There was no gouty tophus at the MTP joint. [scielo.br]

Figure 1 Monosodium urate monohydrate crystals from a gouty tophus viewed under polarised light. [doi.org]

Xanthoma

Gouty tophus was considered as the fibrillary material was crystalline and birefringent, and resembled urate crystals, but the overall histological and clinical findings did [racgp.org.au]

Great toe gouty tophus-like lesion revealing extensive tendon xanthomatosis in a asymptomatic hyperuricemic patient. J Postgrad Med. 2013 Jul-Sep. 59(3):238-9. [emedicine.medscape.com]

Morton Neuroma

tophus, rheumatoid bursae and nodules • Vascular pathology, e.g. ischaemia, venous and lymphatic insufficiency • Neurological problems, e.g. sensory dysfunction, nerve entrapment [medical-dictionary.thefreedictionary.com]

• One or more synovial pathologies such as nodules and ganglions, capsulitis, gouty tophus, adventitious bursitis, rheumatoid bursae etc. • One or more vascular pathologies [runnerclick.com]

[…] plantar hyperkeratosis • Connective tissue pathology, e.g. plantar fibromatosis, plantar plate rupture • Synovial pathology, e.g. ganglion, adventitious bursitis, capsulitis, gouty [medical-dictionary.thefreedictionary.com]

Epidermoid Cyst

DDx: Pilar cyst - indistinguishable on gross. [2] Melanoma. [3] Gouty tophus. Image Epidermal inclusion cyst. [librepathology.org]

Cervical Cord Compression

Histological examination of the surgical specimen demonstrated a gouty tophus. [ncbi.nlm.nih.gov]

To report a case of myelopathy due to intradiscal gouty tophus. Spinal involvement in gout is uncommon. [ncbi.nlm.nih.gov]

Juvenile Seronegative Polyarthritis

[…] gout Urate tophus of heart+ ( I43.8* ) M10.1 Lead-induced gout M10.2 Drug-induced gout Use additional external cause code (Chapter XX), if desired, to identify drug. [apps.who.int]

+ ) M09.8* Juvenile arthritis in other diseases classified elsewhere M10 Gout [See site code at the beginning of this chapter ] M10.0 Idiopathic gout Gouty bursitis Primary [apps.who.int]

Familial Calcium Pyrophosphate Deposition

This is a surgically proven gouty tophus. [radsource.us]

Gouty tophi are more faintly calcified and are associated with elevated urate levels, though the MRI appearance of a tophus can be indistinguishable from a deposit of CHA [radsource.us]

Proliferating Angioendotheliomatosis

Cutaneous angiosarcoma arising in a gouty tophus: report of a unique case and a review of foreign material-associated angiosarcomas. Am J Dermatopathol 2000;22:418-421. [uscapknowledgehub.org]

tophus. [ 18 ] Angiosarcoma can also rarely arise in nerve sheath tumors including schwannoma and malignant peripheral nerve sheath tumor (usually in the course of NF1), [uscapknowledgehub.org]

[…] metal (bullet, [ 12 ] shrapnel, [ 13, 14 ] orthopedic fixation plate, [ 15 ] hip replacement prosthesis, [ 16 ] iron injection [ 17 ] ), sponge mesh, bone wax [ 12 ] and gouty [uscapknowledgehub.org]

Milker's Nodes

Tophus Granuloma Pyogenicum Hidrocystoma Keloids in Scars Keratoacanthoma Merkel Cell Carcinoma Milker's Nodule Molluscum Contagiosum Nevocytic Nevus Pilomatricoma Sebaceous [skincancer.dermis.net]

Basal Cell Carcinoma: Acanthoma Fissuratum Amelanotic Malignant Melanoma (AMM) Chondrodermatitis Nodularis Chronica Helicis (Winkler) Clear Cell Acanthoma Degos Cylindroma Gouty [skincancer.dermis.net]

Hyperuricemia

View Article PubMed Google Scholar McCarty DJ: A historical note: Leeuwenhoek's description of crystals from a gouty tophus. Arthritis Rheum. 1970, 13: 414-418. [doi.org]

Antonie van Leeuwenhoek (1632–1723), one of the pioneers of microscopy, was the first to describe the appearance of the crystals from a gouty tophus, although their chemical [tandfonline.com]

Aside from gouty arthritis and tophus formation, renal disease is the most frequent complication of hyperuricemia. [themedicalbiochemistrypage.org]

Warty Dyskeratoma

tophus ( DX ). borderline lesions: premalignant keratosis (PMK) mimics BCC [S-01-8239]. other malignant lesions: malignant fibrous histiocytoma (MFH) mimics SCC; MFH must [palpath.com]

[…] stroma not filled with plasma cells & papillary stalks which can extend through a surface pore "like a hermit crab". other: chondrodermatiis nodularis chronica helicis (CNCH) gouty [palpath.com]

Spinal Cord Compression

Objective: Our aim was to present a case of myelopathy due to thoracic spinal gouty tophus. [nature.com]

The first case of myelopathy secondary to cord compression by a gouty tophus was reported by Koskoff et al. in 1953 [1]. [academic.oup.com]

Thoracic spinal cord compression by a gouty tophus. Case report. Review of the literature. Neurochirurgie 1999; 45 : 402–406. 19. [nature.com]

Tumoral Calcinosis

tophus. [healio.com]

Excised material consisted of precipitation of calcium salts without any evidence of gouty tophus and was diagnosed histopathologically as calcinosis. [healio.com]

[…] laboratory findings were not completely supportive, the long, periodic, and relatively benign clinical course of the disease implied that there was a crystal deposition such as gouty [healio.com]

Tarsal Tunnel Syndrome

Gouty tophus of the tarsal tunnel is a rare cause of posterior tarsal tunnel syndrome. [ncbi.nlm.nih.gov]

We present a case of acute posterior tarsal tunnel syndrome due to gouty tophus that required early tarsal tunnel release in order to avoid irreversible nerve damage. [ncbi.nlm.nih.gov]

Calcium Pyrophosphate Arthropathy

Radiologic case study: Gouty tophus involving the distal quadriceps tendon. Orthopedics. 2004;27:90-92. Miller LJ, Pruett SW, Losada R, et al. [appliedradiology.com]

Olecranon Bursitis

A gouty tophus occasionally mimics an infectious or neoplastic process and MRI must be obtained under these circumstances [7]. [hindawi.com]

If: the patients hands or elbows look like this, a red, hot, and swollen olecranon may be due to acute gouty bursitis. In this case, the gouty tophus was asymptomatic. [journals.lww.com]

Secondary Amyloidosis

Inspection of the hands revealed swelling and enlargement of the proximal interphalangeal joints, and a gouty tophus was visible on the tragus of the right ear. [acgcasereports.gi.org]

Congenital Longitudinal Deficiency of the Ulna

tophus, 49 osteoarthritic or rheumatoid narrowing of the ulnar groove, constriction of the ulnar nerve as it passes behind the medial epicondyle causing frictional neuritis [clinicalgate.com]

[…] over the medial epicondyle, 48 cubitus valgus, malunited supracondylar fracture, bony spurs and osteophytes, joint deformity in osteoarthritis or rheumatoid arthritis or gouty [clinicalgate.com]

Chondroma

It is also appropriate to eliminate some benign lesions such as tumor calcinosis, a synovial chondromatosis, a gouty tophus, a lipoma containing areas of metaplasia chondroid [panafrican-med-journal.com]

Carpal Tunnel Syndrome

The surgery combined with decreasing trioxypurine treatment can improve the treatment outcome of gouty tophus. [ncbi.nlm.nih.gov]

We removed partial of gouty tophus and retained the integrity of the tendon. Two years after the surgery, the patient had not experienced any symptom recurrence. [ncbi.nlm.nih.gov]