Possible Causes for Grapefruit Juice Acetaminophen Overdose Acetaminophen (Tylenol) is a pain medicine. Acetaminophen overdose occurs when someone accidentally or intentionally takes more than the normal or recommended amount of this medicine. Acetaminophen overdose is one of the most common poisonings. People often think that this medicine is very safe. However, it can be[…] [medlineplus.gov] Cisapride Poisoning Do not consume grapefruit or grapefruit juice while taking cisapride. [drugs.com] Grapefruit products may increase amount of cisapride available in your body, which could lead to dangerous side effects. What should I do if I forget a dose? [cisapride.com] Avoid alcohol, smoking, elevate head of the bed, avoid large meals before bed, lose weight, and avoid fatty foods, chocolate, caffeine, or grapefruit and grapefruit juice. [pfusion.net] Cyclosporine Toxicity The liquid form must be diluted for use, preferably mixed with room temperature orange or apple juice. Do not mix with grapefruit juice. [psoriasis.org] You should not have grapefruits or grapefruit juice while getting cyclosporine. [nephcure.org] Avoid grapefruit juice. [labtestsonline.org] Colchicine Poisoning juice. [symptoma.com] DRUG INTERACTIONS: CYP 3A4 and P-glycoprotein inhibitors, such as clarithromycin, erythromycin, ketoconazole, ciclosporin, and natural grapefruit juice can increase colchicine [ncbi.nlm.nih.gov] Concomitant use of strong CYP3A4 and/or P-gp inhibitors (e.g., clarithromycin, cyclosporine, diltiazem, protease inhibitors, grapefruit juice and many others) elevate colchicine [dpic.org] Drug-Induced Myopathy If this is the case for you, your doctor will likely start by ruling out other factors that might be contributing to your pain, such as: strenuous exercise grapefruit juice [healthline.com] juice, should be assessed. [care.diabetesjournals.org] juice may predispose patients to muscle breakdown. 17-19 Drug-Dependent: The risk of statin-associated myopathy has been shown to increase as a patient’s statin dose increases [uspharmacist.com] Biliary Disorder In the evening, drink a mixture of olive oil and grapefruit juice to stimulate bile secretion Day 7: purge again with Epsom salt and plan to stay home and have easy access [santi-shop.eu] Lovastatin Grapefruit juice increases the bioavailability of several drugs known to be metabolized by CYP3A4. [ncbi.nlm.nih.gov] Abstract Background Grapefruit juice increases the bioavailability of several drugs known to be metabolized by CYP3A4. [doi.org] The effect of the same grapefruit juice and water regimen on the pharmacokinetics of midazolam (2 mg oral dose given 1 hour after the third day of grapefruit juice and water [dx.doi.org] Methylergonovine Do not eat grapefruit or drink grapefruit juice while you are using this medicine. [mayoclinic.org] Less potent inhibitors include saquinavir, nefazodone, fluconazole, grapefruit juice, fluoxetine, fluvoxamine, zileuton, and clotrimazole. [druglib.com] Grapefruit and grapefruit juice may change the amount of this medicine that is absorbed in the body. [mayoclinic.org] Nicergoline Poisoning Examples of less potent CYP 3A4 inhibitors include: saquinavir, nefazodone, fluconazole, fluoxetine, grapefruit juice, fluvoxamine, zileuton, metronidazole, and clotrimazole [ndrugs.com] Cyclosporine These interactions involve various drugs and food constituents, including antibiotics, antifungal agents, calcium antagonists, dietary lipids, and grapefruit juice. 1 2 Grapefruit [bloodjournal.org] Avoid grapefruit and grapefruit juice while taking cyclosporine. Cyclosporine can raise the levels of potassium in your blood. [psoriasis.org] Grapefruit juice may decrease the metabolism of cyclosporin. Do not increase or decrease your intake of grapefruit juice without the advice of your doctor or pharmacist. [healthhub.sg] Dofetilide juice may increase levels; avoid concurrent use Magnesium and potassium serum levels should be maintained within normal range to avoid QTc prolongation [reference.medscape.com] Grapefruit juice: May decrease hepatic metabolism and increase plasma levels. Tell patient not to use together. [glowm.com] juice, nefazodone, norfloxacin, quinine, zafirlukast); these may increase dofetilide levels. [empr.com] OxyContin Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. [webmd.com] Grapefruit juice can increase the amount of oxycodone in your body so it's a good idea to avoid it while you're taking oxycodone. [nhs.uk] Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details. [webmd.com] Sirolimus By comparison, the grapefruit juice drinkers needed between 25 and 35 mg of sirolimus per week. [oncologynurseadvisor.com] Grapefruit juice: decreased sirolimus metabolism and increased blood level Drug-herbs. Astragalus, echinacea, melatonin, St. [medical-dictionary.thefreedictionary.com] You should not eat grapefruit or drink grapefruit juice while you are taking this medicine. [mayoclinic.org] Amiodarone Grapefruit juice should be avoided during treatment with amiodarone. [medicinenet.com] Do not drink grapefruit juice during treatment with amiodarone. Grapefruit juice affects how amiodarone is absorbed in the stomach. [rxwiki.com] Grapefruit juice may reduce the breakdown of amiodarone in the stomach leading to increased amiodarone blood levels. [medicinenet.com] Statin The grapefruit effect Grapefruit juice affects certain statins more than others. [health.harvard.edu] juice. [ncbi.nlm.nih.gov] Even patients who enjoy grapefruit juice do not ingest more than one quart each day! [aafp.org] Dimethindene Maleate Poisoning If the patient shows any risk factor, such as special diet (grapefruit juice), hepatic disease, electrolytic disturbance, and use of anti-arrhythmic drugs with potential of [medcraveonline.com] Loxapine Mix the medicine with orange juice or grapefruit juice before drinking. Dosing The dose of this medicine will be different for different patients. [mayoclinic.org] Avoid large amounts of grapefruit or grapefruit juice while you are taking Buspar. [antigenpharma.com] Avoid large amounts of grapefruit or grapefruit juice while you are taking Loxapin. [ndrugs.com] Vitamin C Intake juice 1 grapefruit 1 cup strawberries 2 cups watermelon 1 cup raw or cooked cauliflower 1/2 cup raw or cooked broccoli 1/2 green pepper 1/2 read pepper [thedietchannel.com] Foods that provide vitamin C include: 6 ounces orange juice: 62 to 93 mg 6 ounces grapefruit juice: 62 to 70 mg one kiwi: 91 mg 1/2 cup raw, sweet red bell pepper, chopped [babycenter.com] […] key to getting abundant antioxidants and disease-fighting phytochemicals. 1 orange 1 guava 2 kiwis 1 cup cooked spinach 2 cups raw spinach 1 cup cantaloupe 1 mango 1/2 cup grapefruit [thedietchannel.com] Pravastatin Usually, consuming grapefruit products such as grapefruit juice and grapefruit supplement along while taking lipid-lowering statins is contraindicated. [drugsdb.com] Duration of effect of grapefruit juice on the pharmacokinetics of the CYP 3A4 substrate simvastatin. [doi.org] […] with grapefruit juice. [worstpills.org] Amlodipine Don’t eat or drink lots of grapefruit or grapefruit juice while you’re taking amlodipine. [lloydspharmacy.com] Grapefruit contains something that can increase the concentration of amlodipine in your body and would make it more likely to get side effects. [lloydspharmacy.com] Eplerenone juice.1 Tolerability: Side effects are uncommon with eplerenone. [aafp.org] Talk to your doctor about drinking grapefruit juice while taking this medicine. Do not use salt substitutes containing potassium while you are taking eplerenone. [medlineplus.gov] juice. 1 Tolerability: Side effects are uncommon with eplerenone. [aafp.org] Guanfacine […] and grapefruit juice CYP3A4 inducers, such as rifampin (Rifadin), which is an antibiotic valproic acid (Depakene), an anticonvulsant medication medications used to treat [healthline.com] [Examples of 'strong' (clarithromycin, ketoconazole, nefazodone) and 'moderate' (doxycycline, fluvoxamine, grapefruit juice) CYP3A4 inhibitors.]" [aap.org] Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medication. Take the missed dose as soon as you remember it. [medlineplus.gov] Urate Kidney Stone Apple juice and grapefruit juice showed no correlation. [theatlantic.com] juice and soda. [kidney.org] Would drinking lots of grapefruit juice affect a PSA reading? My husband's PSA reading jumped from a 4.2 to a 17 in @ 2 years' time. How can that be? [medical-dictionary.thefreedictionary.com] Tick Paralysis By Richard Klasco, M.D Photo Credit Can Grapefruit Juice Affect My Thyroid Medicine? [nytimes.com] Some 100 drugs can have dangerous and even life-threatening effects if you eat grapefruit or drink grapefruit juice while taking them. [nytimes.com] Nadolol To evaluate effects of itraconazole, rifampicin and grapefruit juice on pharmacokinetics and pharmacodynamics of a hydrophilic non-selective β-adrenoceptor blocker nadolol [ncbi.nlm.nih.gov] Grapefruit and its juice have also been shown to affect the strength of cholesterol and blood pressure medications, according to HealthDay. [medicaldaily.com] juice grass pollen allergen extract guanethidine HIV protease inhibitors (e.g., nelfinavir, ritonavir, saquinavir) insulin lanreotide lapatinib levodopa licorice lidocaine [uniprix.com] Vasodilator juice There are certain substance which counteract the effects of some vasodilators and increase blood pressure. [pharmaceutical-drug-manufacturers.com] Don’t eat grapefruit or drink grapefruit juice. Take your medicine exactly as directed. Keep all follow-up appointments. [saintlukeskc.org] Points to remember Grapefruit juice may impair absorption of some calcium channel blockers and therefore should not be consumed for 2 hours before and 4 hours after taking [rheumaderm-society.org] Emend juice guanfacine HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs; e.g., delavirdine, efavirenz, etravirine, nevirapine) HIV protease inhibitors (e.g., atazanavir [medbroadcast.com] • Avoid grapefruit juice. • If an oral dose is missed, do not double up on doses. [tahoecancercenter.com] juice haloperidol HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs; e.g., delaviridine, efavirenz, etravirine, nevirapine) HIV protease inhibitors (e.g., atazanavir [chealth.canoe.com] Ergotamine Withdrawal Eating grapefruit or drinking grapefruit juice may affect the amount of Avamigran in your blood. [algeria-pharmacy.org] Food: Grapefruit juice may increase toxicity. Absorption: Variable absorption orally. Peak: 0.5–3 h. Distribution: Crosses blood–brain barrier. [robholland.com] Examples of less potent CYP 3A4 inhibitors include: saquinavir, nefazodone, fluconazole, fluoxetine, grapefruit juice, fluvoxamine, zileuton, metronidazole, and clotrimazole [rxlist.com] Dutasteride Food and Drug Interactions Do not eat grapefruit or drink grapefruit juice while taking this medicine.Grapefruit and grapefruit juice may raise the levels of dutasteride in [upmc.com] Talk to your doctor about drinking grapefruit juice while taking this medicine. [medlineplus.gov] Household Cleaner Combining fresh grapefruit or other citrus fruit juice with the vinegar can help mask the acidic vinegar smell. [blog.pittmandavis.com] Spray Floor Cleaner Grapefruit juice gives this floor cleaner a great scent. [diyncrafts.com] To make simple household cleaner combine one part vinegar to four parts hot water, mix in from grapefruit juice and baking soda and let it sit for a few minutes. [blog.pittmandavis.com]
