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158 Possible Causes for Gynecomastia, Portal Hypertension, Testicular Atrophy

  • Hemochromatosis

    Nonarticular manifestations Physical exam findings include hepatomegaly, extrahepatic manifestations of chronic liver disease, testicular atrophy, gynecomastia, loss of body[rheumatologyadvisor.com] […] vein (portal hypertension), which is the main vein that carries blood from the intestines to the liver.[rarediseases.org] Testicular atrophy, sometimes caused by excessive iron deposition in the testes, is a risk factor for testicular cancer.[ncbi.nlm.nih.gov]

  • Hepatitis C

    atrophy.[symptoma.com] […] and portal hypertension based on evidence in literature, including randomized clinical trials and met-analyses.[idsociety.org] As cirrhosis develops, symptoms and signs increase and may include: Elevated liver enzymes in the blood Weakness Loss of appetite Weight loss Breast enlargement in men ( gynecomastia[medicinenet.com]

  • Portal Cirrhosis

    Increased Estrogen: Increased levels of estrogen in those with cirrhosis can result in development of spider telangiectasias , as well as testicular atrophy in men End-stage[pathwaymedicine.org] ., gynecomastia , hypogonadism ).[amboss.com] […] of various portal hypertensive dis orders, has clearly been achieved by these excellent contributions.[books.google.com]

  • Chronic Alcoholism

    ENDOCRINE – Cirrhosis leading to gynecomastia and testicular atrophy, amenorrhea/infertility. Alcohol can also cause hypoglycemia in alcoholics.[errolozdalga.com] Fibrosis narrows the terminal hepatic venules, compromising hepatic perfusion and thus contributing to portal hypertension .[merckmanuals.com] For men, a large number of epidemiological studies evidenced that excessive alcohol consumption is associated with impaired testosterone production and testicular atrophy.[ri.conicet.gov.ar]

  • Liver Cirrhosis

    atrophy (shrinking) and impotence in males or amenorrhoea (no periods) in women cognitive problems such as memory loss, confusion or concentration difficulties.[betterhealth.vic.gov.au] Cirrhosis signs, include jaundice, gynecomastia (up to one third of men), loss of axillary and pubic hair, ascites, and splenomegaly (due to portal hypertension), finger clubbing[symptoma.com] This case report is of a 32-year-old woman of African descent on follow-up for pregnancy in the background of portal hypertension due to liver cirrhosis.[ncbi.nlm.nih.gov]

  • Spironolactone

    atrophy.[psychology.wikia.com] A study of the histopathology of human gynecomastia. J Clin Endocrinol Metab 1971;32:173-8. Narual HS, Carlson HE. Gynecomastia.[ebmconsult.com] Spironolactone lowers portal hypertension by inhibiting liver fibrosis, ROCK-2 activity and activating NO/PKG pathway in the bile-duct-ligated rat.[abcam.com]

  • Adrenocortical Carcinoma

    Oestrogen production occurs in 1% to 3% of male ACC patients, causing gynaecomastia and testicular atrophy. 2.[endocrinesurgery.net.au] We herein present a 60-year-old man with adrenocortical carcinoma who had gynecomastia.[ncbi.nlm.nih.gov] […] of portal hypertension or clinical stigmata of such including but not limited to gastric or esophageal varices, umbilical vein varices or telangectasias.[clinicaltrials.gov]

  • Hepatocellular Carcinoma

    , in that the hormonal influence of the fibrolamellar cancer cells cause the gynecomastia.[fibrofoundation.org] Multivariate analyses identified that platelet count, ICG-R15, clinically significant portal hypertension, and major resection were independent factors for predicting severe[ncbi.nlm.nih.gov] This includes jaundice, caput medusa, spider angiomata, asterixis , palmar erythema, peripheral edema, gynecomastia, and testicular atrophy.[symptoma.com]

  • Liver Disease

    atrophy (and how do you know, what is normal?)[stanfordmedicine25.stanford.edu] It can complicate chronic liver disease of any etiology, but is most commonly associated with portal hypertension.[ncbi.nlm.nih.gov] Symptoms of cirrhosis of the liver include: easy bruising may occur due to decreased production of clotting factors; bile salts can deposit in the skin causing itching ; gynecomastia[medicinenet.com]

  • Chronic Hepatitis

    Breast swelling (gynaecomastia), testicular atrophy, loss of libido and amenorrhoea due to endocrine dysfunction. Confusion and drowsiness (encephalopathy).[patient.info] In advanced stages of chronic hepatitis, features of cirrhosis like hepatosplenomegaly, palmar erythema, parotid enlargement, spider nevi, gynecomastia and even ascites, portal[symptoma.com] hypertension .[radiopaedia.org]

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