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37 Possible Causes for Gynecomastia, Scleral Icterus, Testicular Atrophy

  • Liver Cirrhosis

    atrophy (shrinking) and impotence in males or amenorrhoea (no periods) in women cognitive problems such as memory loss, confusion or concentration difficulties.[betterhealth.vic.gov.au] Cirrhosis signs, include jaundice, gynecomastia (up to one third of men), loss of axillary and pubic hair, ascites, and splenomegaly (due to portal hypertension), finger clubbing[symptoma.com] In the presented case, the authors describe an obese middle-aged man that presented to the emergency department for persistent oedema, scleral icterus and fatigue.[ncbi.nlm.nih.gov]

  • Portal Cirrhosis

    Increased Estrogen: Increased levels of estrogen in those with cirrhosis can result in development of spider telangiectasias, as well as testicular atrophy in men End-stage[pathwaymedicine.org] ., gynecomastia, hypogonadism ).[amboss.com] icterus Vascular spiders (spider telangiectasias, spider angiomata) Splenomegaly Testicular atrophy TABLE 2 Common Physical Examination Findings in Patients with Cirrhosis[aafp.org]

  • Hemochromatosis

    Testicular atrophy, sometimes caused by excessive iron deposition in the testes, is a risk factor for testicular cancer.[ncbi.nlm.nih.gov] Men: Impotence, loss of libido, gynecomastia, testicular atrophy. Women: Amenorrhea and loss of libido.[pathwaymedicine.org] Nonarticular manifestations Physical exam findings include hepatomegaly, extrahepatic manifestations of chronic liver disease, testicular atrophy, gynecomastia, loss of body[cancertherapyadvisor.com]

  • Isoniazid Hepatitis

    […] distress, pancreatitis, blood dyscrasias, hypersensitivity reactions (eg, skin eruptions, TEN, DRESS), pyridoxine deficiency, hyperglycemia, pellagra, metabolic acidosis, gynecomastia[clinicaladvisor.com] icterus, or “hepatitis” notation 5300 15 (0.37%) b 1 (.019%) Nolan 6 Jan. 1989 to 1 December 1995 Monthly symptom-based screening AST 5x normal with symptoms, and no other[mdedge.com] […] reactions CNS: peripheral neuropathy, dizziness, memory impairment, slurred speech, psychosis, toxic encephalopathy, seizures EENT: visual disturbances GI: nausea, vomiting GU: gynecomastia[medical-dictionary.thefreedictionary.com]

  • Liver Failure

    […] a star of David) Drowsiness and confusion Parotid gland enlargement Spider angiomas Icterus Bilateral parotid swelling ( Credit ) Diminished axillary hair Spider angioma Gynecomastia[stanfordmedicine25.stanford.edu] icterus Vascular spiders (spider telangiectasias, spider angiomata) Splenomegaly Testicular atrophy TABLE 2 Common Physical Examination Findings in Patients with Cirrhosis[aafp.org] In males, this can lead to enlarged breasts (gynecomastia) and shrunken testicles, while women may find their menstrual cycle is affected.[news-medical.net]

  • Hepatocellular Carcinoma

    This includes jaundice, caput medusa, spider angiomata, asterixis , palmar erythema, peripheral edema, gynecomastia, and testicular atrophy.[symptoma.com] , in that the hormonal influence of the fibrolamellar cancer cells cause the gynecomastia.[fibrofoundation.org] This includes jaundice, caput medusa, spider angiomata, asterixis , palmar erythema, peripheral edema, gynecomastia, and testicular atrophy.[symptoma.com]

  • Liver Disease

    atrophy (and how do you know, what is normal?)[stanfordmedicine25.stanford.edu] Symptoms of cirrhosis of the liver include easy bruising may occur due to decreased production of clotting factors; bile salts can deposit in the skin causing itching; gynecomastia[medicinenet.com] atrophy Temporal wasting Hypertrophic osteoarthropathy Dupuytren contracture Fetor hepaticus ARVs and Hepatotoxicity Many ARVs may cause liver damage, particularly in patients[hiv.va.gov]

  • Macronodular Cirrhosis

    atrophy in males (chronic liver disease, hemochromatosis) EXTREMITIES: Pedal edema (hypoalbuminemia, failure of right side of the heart), arthropathy (hemochromatosis) NEUROLOGIC[encyclopedia.lubopitko-bg.com] […] biliary excretion (jaundice, pruritus) Impaired nitrogen metabolism (hepatic encephalopathy) Impaired estrogen metabolism (palmar erythema, spider nevus, testicular atrophy, gynecomastia[pathologyoutlines.com] Increased Estrogen: Increased levels of estrogen in those with cirrhosis can result in development of spider telangiectasias, as well as testicular atrophy in men End-stage[pathwaymedicine.org]

  • Cryptogenic Cirrhosis

    […] biliary excretion (jaundice, pruritus) Impaired nitrogen metabolism (hepatic encephalopathy) Impaired estrogen metabolism (palmar erythema, spider nevus, testicular atrophy, gynecomastia[pathologyoutlines.com] atrophy in male patients; and many other symptoms.[fattyliverdiseasecures.com] […] through a provided list of clinical stigmata of chronic liver disease and cirrhosis including spider angiomata, palmar erythema, finger clubbing, Dupuyetren’s contracture, gynecomastia[omicsonline.org]

  • Alcoholic Hepatitis

    atrophy Loss of body hair Signs of ‘pseudo- Cushings ’ (red face, hump, striae) Face /skin Parotid enlargement Spider naevi Easy bruising Dupuytren’s contracture Neuromuscular[almostadoctor.co.uk] Often patients have co-existence of alcoholic hepatitis and cirrhosis with clinical features such as spider telangiectasia, parotid enlargement, gynecomastia.[euroliver.org] Physical Exam: VS: T 98.9 HR 104 RR 19 BP 117/67 O2 99% RA Gen: Well-appearing obese female in no acute distress HEENT: PERRL, marked scleral icterus, sublingual icterus,[ddxof.com]

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