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60 Possible Causes for Gynecomastia, Vitamin B6 Deficiency

  • Isoniazid

    The isoniazid was discontinued, and the gynecomastia was partially resolved by the end of treatment. Four years later, gynecomastia was not detected.[ncbi.nlm.nih.gov] As her serum vitamin B6 level was remarkably low, she was diagnosed with convulsive seizures due to vitamin B6 deficiency associated with isoniazid treatment.[ncbi.nlm.nih.gov] B6 deficiency, which can lead to polyneuritis .[flexikon.doccheck.com]

  • Chronic Alcoholism

    ENDOCRINE – Cirrhosis leading to gynecomastia and testicular atrophy, amenorrhea/infertility. Alcohol can also cause hypoglycemia in alcoholics.[errolozdalga.com] Folic acid and vitamins B6 and B12 deficiency may lead to hyperhomocysteinemia, as they participate in its metabolism.[ncbi.nlm.nih.gov] Alcoholic Liver Disease Physical Examination Constitutional Fever Skin Spider angioma Parotid and lacrimal gland enlargement Palmer erythema Jaundice Decreased body hair Gynecomastia[clevelandclinicmeded.com]

  • Endocrine Dysfunction

    Abstract Therapy with spironolactone is often associated with estrogenlike side-effects, including impotence and gynecomastia in men and menstrual irregularity in women.[annals.org] Bone density (DXA and CT) Trace elements: zinc, copper, and selenium Vitamins B1, B6, B12, C, E, and A; also pyridoxine, carnitine, methylmalonic acid, and homocysteine.[thalassemia.com] Fasting glucose (semiannually) Oral glucose tolerance testing as indicated by fasting glucose (see the following section) IGF-1 and IGF BP-3 to screen for growth hormone deficiency[thalassemia.com]

  • Isoniazid Hepatitis

    […] distress, pancreatitis, blood dyscrasias, hypersensitivity reactions (eg, skin eruptions, TEN, DRESS), pyridoxine deficiency, hyperglycemia, pellagra, metabolic acidosis, gynecomastia[clinicaladvisor.com] It is believed that isoniazid competes with pyridoxyl phosphate for the enzyme apotryptophanase which may lead to symptoms of pyridoxine (vitamin B6) deficiency.[rxmed.com] […] reactions CNS: peripheral neuropathy, dizziness, memory impairment, slurred speech, psychosis, toxic encephalopathy, seizures EENT: visual disturbances GI: nausea, vomiting GU: gynecomastia[medical-dictionary.thefreedictionary.com]

  • Penicillamine

    Reversible gynecomastia associated with d-penicillamine in a man with rheumatoid arthritis. BMJ . 1982; 285:1083-4. [IDIS 159628] [PubMed 6812755] 204.[web.archive.org] Vitamin B6 Penicillamine may increase vitamin B6 excretion, reduce activity, and increase the risk for vitamin B6 deficiency.[wa.kaiserpermanente.org] Reversible gynecomastia associated with d-penicillamine in a man with rheumatoid arthritis. BMJ . 1982; 285:1083-4. 204.[drugs.com]

  • Ethionamide

    Gynecomastia due to ethionamide was suspected and the patient was advised anti-inflammatory drugs for 5 days without any change in drug therapy.[ncbi.nlm.nih.gov] B6 deficiency / Delayed / Incidence not known DRUG INTERACTIONS Aminosalicylate sodium, Aminosalicylic acid: (Moderate) Careful monitoring of hepatic function is recommended[pdr.net] Hypothyroidism, gynecomastia, alopecia, impotence also have been reported.[antimicrobe.org]

  • Alcoholic Liver Disease

    […] gain malnutrition and wasting anorexia fatigue confusion pruritus fever nausea and vomiting finger clubbing Dupuytren contracture leg swelling parotid gland enlargement gynecomastia[online.epocrates.com] It is important to note that AST and ALT levels are not markedly elevated ( 300 IU/L) and the AST to ALT ratio is 2, as ALT is low due to deficiency of vitamin B6 as a result[symptoma.com] Alcoholic Liver Disease Physical Examination Constitutional Fever Skin Spider angioma Parotid and lacrimal gland enlargement Palmer erythema Jaundice Decreased body hair Gynecomastia[clevelandclinicmeded.com]

  • Seborrheic Dermatitis

    ., gynecomastia), sexual dysfunction, and infertility in males.[en.wikipedia.org] Deficiency of vitamins pyridoxine (vitamin B6), biotin, and riboflavin (vitamin B2) can also cause it.[symptoma.com] B2, B6, B12 and biotin deficiency. 8-16 Nevertheless, up to the present date the association between SD and nutritional deficiencies has yet to be confirmed. 17 Sudan defended[scielo.br]

  • Liver Cirrhosis

    Cirrhosis signs, include jaundice, gynecomastia (up to one third of men), loss of axillary and pubic hair, ascites, and splenomegaly (due to portal hypertension), finger clubbing[symptoma.com] deficiency (vitamin B12, vitamin B6 and folate), chronic disease (chronic liver disease, chronic kidney disease, hypothyroidism) or due to a genetic variant in the methylenetetrahydrofolate[dx.doi.org] […] a star of David) Drowsiness and confusion Parotid gland enlargement Spider angiomas Icterus Bilateral parotid swelling ( Credit ) Diminished axillary hair Spider angioma Gynecomastia[stanfordmedicine25.stanford.edu]

  • Oral Contraceptive

    Gynecomastia in the newborn induced by maternal milk? An unusual complication of oral contraceptives]. Nouv Presse Med. 1974;3:2579. PMID: 4467130 10.[drugs.com] Taking oral contraceptives contributes to nutrient deficiencies, including vitamins B2, B6, B12, and C; folic acid 16 , magnesium, selenium, and zinc 9 . Diabetes.[emedexpert.com] The woman stopped the contraception and the gynecomastia disappeared completely in about 4 weeks.[9] The contraceptive possibly caused the breast enlargement.[drugs.com]

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