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160 Possible Causes for Haptoglobin Decreased, Jaundice, Mild Anemia

  • Thalassemia

    Diagnostic methods Diagnosis is suspected in infants younger than 2 years of age with severe microcytic anemia, mild jaundice and hepatosplenomegaly.[orpha.net] Mild anemia can make you feel tired. Mild anemia caused by alpha thalassemia trait might be mistaken for iron-deficiency anemia.[web.archive.org] Reticulocytes, LDH and bilirubin are increased; haptoglobin is decreased.[lecturio.com]

  • Hereditary Spherocytosis

    This case also highlights the fact that physicians should consider concomitant hemolytic disease in patients in whom jaundice and infections that rarely cause jaundice coexist[ncbi.nlm.nih.gov] A 27-year-old Nigerian woman presented with mild anemia, jaundice, splenomegaly and a history of multiple blood transfusion.[ncbi.nlm.nih.gov] Routine chemistry testing  Bilirubin: Increased  Indirect bilirubin  Urine urobilinogen: increased  Methaemalbumin: Increased  LDH: Increased  Haptoglobin: Decreased[slideshare.net]

  • Alpha-Thalassemia

    Alpha-thalassemia Alpha-thalassemia inheritance pattern Specialty Hematology Symptoms Jaundice, Fatigue Anie KA, Massaglia P (March 2014).[en.wikipedia.org] The heterozygous form may be asymptomatic or marked by mild anemia. β-thalassemia ( beta-thalassemia ) that caused by diminished synthesis of beta chains of hemoglobin.[medical-dictionary.thefreedictionary.com] Reticulocytes, LDH and bilirubin are increased; haptoglobin is decreased.[lecturio.com]

  • Cooley's Anemia

    Children develop life-threatening anemia, have failure to thrive, and may develop jaundice.[secure.ssa.gov] People with Cooley's anemia make less hemoglobin and fewer circulating red blood cells than normal, which results in mild or severe anemia.[blood.emedtv.com] Splenomegaly, episodes of jaundice and roentgenologic evidence of bone involvement were prominent features.[jamanetwork.com]

  • Hemolytic Anemia

    The existence of a primary form of acquired hemolytic jaundice has been questioned more and FULL TEXT[annals.org] All the children presented with neonatal hemolytic anemia. Beyond the neonatal period, they did not have jaundice or hemolysis, but continued to have mild anemia.[ncbi.nlm.nih.gov] The diagnosis is established by reticulocytosis, increased unconjugated bilirubin and lactate dehydrogenase, decreased haptoglobin, and peripheral blood smear findings.[ncbi.nlm.nih.gov]

  • Hemoglobin C Disease

    In some cases, jaundice may occur. Some people may develop gallstones that need to be treated. In most cases, no treatment is needed.[nlm.nih.gov] Hemoglobin C disease is a hemoglobinopathy causing mild hemolytic anemia.[symptoma.com] […] or absent haptoglobin, elevated LDH and unconjugated bilirubin, and elevated serum free hemoglobin.[clinicaladvisor.com]

  • Haemoglobin E Disease

    While evaluating the patients of jaundice, we came across two cases of hemoglobin E (Hb E) disorders.[ijpmonline.org] Homozygotes display mild hemolytic anemia and splenomegaly (enlarged spleen). The HbCSpr trait is asymptomatic.[wikilectures.eu] Patients come to the hospital because of anemia, fever, abdominal mass, and jaundice.[journals.lww.com]

  • Pyruvate Kinase Deficiency

    Pyruvate kinase deficiency may cause pregnancy-associated jaundice.[ncbi.nlm.nih.gov] Patients presenting with hemolytic anemia, either severe or mild hemolytic anemia, should be screened for PKD in the first year of life.[ncbi.nlm.nih.gov] PAGE BREAK Patients who achieved at least 1 g/dL increase in hemoglobin also demonstrated an increase in haptoglobin and decrease in lactate dehydrogenase in the first weeks[healio.com]

  • Hereditary Elliptocytosis

    As neonates, the nine relatives did not have any significant jaundice or anemia that was recognizable.[ncbi.nlm.nih.gov] The patient presented for a general check up when his CBC showed only mild anemia with slightly increased reticulocytes.[ncbi.nlm.nih.gov] People with this disease can develop anemia, jaundice, and gallstones. Call your provider if you have jaundice that does not go away or symptoms of anemia or gallstones.[nlm.nih.gov]

  • Autoimmune Hemolytic Anemia

    Secondary AIHA might not be diagnosed appropriately because the obstructive jaundice observed in type 1 AIP/IgG4-SC can obscure the presence of hemolytic jaundice.[ncbi.nlm.nih.gov] anemia and are more likely to have spontaneous remissions of the disease with resolution in 6 months, thus intervention may be minimal or unnecessary in these groups.[pedclerk.bsd.uchicago.edu] , and haptoglobin decreased to less than 8 mg/dL.[ncbi.nlm.nih.gov]

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